Development of a high-throughput field phenotyping rover optimized for size-limited breeding fields as open-source hardware

Phenotyping is a critical process in plant breeding, especially when there is an increasing demand for streamlining a selection process in a breeding program. Since manual phenotyping has limited efficiency, high-throughput phenotyping methods are recently popularized owing to progress in sensor and image processing technologies. However, in a size-limited breeding field, which is common in Japan and other Asian countries, it is challenging to introduce large machinery in the field or fly unmanned aerial vehicles over the field.

De novo creation of a naked eye–detectable fluorescent molecule based on quantum chemical computation and machine learning

Designing fluorescent molecules requires considering multiple interrelated molecular properties, as opposed to properties that straightforwardly correlated with molecular structure, such as light absorption of molecules.

Deficiency of the kidney tubular angiotensin II type1 receptor-binding molecule ATRAP exacerbates streptozotocin-induced diabetic glomerular injury via reducing protective macrophage polarisation

Although activation of the renin-angiotensin system and of its glomerular components is implicated in the pathogenesis of diabetic nephropathy, the functional roles of the tubular renin-angiotensin system with AT1 receptor signaling in diabetic nephropathy are unclear.

Impact of the COVID-19 pandemic on cancer diagnosis and resection in a COVID-19 low-burden country: nationwide registration study in Japan

I read a recent article written by Dr. Toes-Zoutendijk et al. that described how the coronavirus disease (COVID)-19 pandemic affected colorectal cancer screening and its incidence in the Netherlands.