Research

Advanced Medical Research Center

Advanced Medical Research Center(SENTANKEN)conducts basic studies aimed at overcoming cancer and lifestyle diseases and translational researches which applies the scientific finding to clinical medicine. It has three omics centers – genomics, proteomics, cellomics –and a biobank, collaborates within YCU and with other research institutions, and promote translational researches. AMRC is also involved in a number of R&D, working with the industry. Our goal is to make our research findings available to the society without delay.

Outline, Structure & Function of the Advanced Medical Research Center >
RESEARCH > ADVANCED MEDICAL RESEARCH CENTER

Message from the Director

The Advanced Medical Research Center (SENTANKEN) of Yokohama City University(YCU) was established in 2006. The assignment of SENTANKEN is to facilitate advanced medical research associated with diseases such as cancer and lifestyle-related diseases. SENTANKEN is focused on basic researches in the field of genomics, proteomics and cellomics, as well as translational researches, which can fill the gap between basic and clinical researches, and promotes not only intramural collaboration but also between government, industry and academia.

Our goal is to make an attractive YCU that can contribute to the community by delivering the research outcomes of our basic and clinical researches promptly to the citizens of Yokohama and by connecting these activities for the revitalization of industries in Yokohama.

Research News

2020-02-13

Loss of p53 drives neuron reprogramming in head and neck cancer

The solid tumour microenvironment includes nerve fibres that arise from the peripheral nervous system. Recent work indicates that newly formed adrenergic nerve fibres promote tumour growth, but the origin of these nerves and the mechanism of their inception are unknown. Here, by comparing the transcriptomes of cancer-associated trigeminal sensory neurons with those of endogenous neurons in mouse models of oral cancer, we identified an adrenergic differentiation signature.
2020-01-20

Visualization of AMPA receptors in living human brain with positron emission tomography

In this study, using the combination of MRT techniques and a unique ex vivo testes organ culture, we show, for the first time, the MRT-mediated TSE for the preservation of spermatogenesis.
2019-10-02

High-precision microbeam radiotherapy reveals testicular tissue-sparing effects for male fertility preservation

In this study, using the combination of MRT techniques and a unique ex vivo testes organ culture, we show, for the first time, the MRT-mediated TSE for the preservation of spermatogenesis.
 
Contact info

E-mail
sentan@yokohama-cu.ac.jp
Our location

3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan

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