Research

Research at Yokohama City University

Yokohama City University strives to contribute to the development of arts and sciences, conduct research activities that contribute to advanced technology, and announce research results to the world with high expertise and from a global point of view. We pride ourselves on research that contributes to state-of-the-art technology through specialization and a global outlook. Aiming to contribute to the advancement of science and the global community, we provide support for an array of global standard research programs.

Research Highlights

2023-05-17

New Study Shows Key Role of Synaptic Plasticity in Modulating Brain Function in Patients with Epilepsy

Using a newly developed radiotracer, researchers find that Hebbian and homeostatic plasticity differentially regulate brain function in epilepsy
2022-03-31

Repeat conformation heterogeneity in cerebellar ataxia, neuropathy, vestibular areflexia syndrome

Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) is a late-onset, slow-progressing multisystem neurodegenerative disorder. Biallelic AAGGG repeat expansion in RFC1 has been identified as causative of this disease, and repeat conformation heterogeneity (ACAGG repeat) was also recently implied. To molecularly characterize this disease in Japanese patients with adult-onset ataxia, we accumulated and screened 212 candidate families by an integrated approach consisting of flanking PCR, repeat-primed PCR, Southern blotting and long-read sequencing using Sequel II, GridION or PromethION.
2022-03-30

Analysis of humoral immunity against emerging SARS-CoV-2 variants: a population-based prevalence study in Yokohama, Japan

Background Little is known about the population prevalence of antibodies against emerging immune escape variants of SARS-CoV-2. Methods A population-based prevalence study was conducted in Yokohama City, the most populous municipality of Japan. Quantitative measurements of immunoglobulin G against SARS-CoV-2 spike protein (SP-IgG) and qualitative measurements of neutralization antibodies against the Omicron BA.1 and BA.2 variants were performed.
 

Researcher Database

A strong research culture is fostered across all disciplines and all departments in Yokohama City University. To learn more about our faculty and their research, click on the link below.