Research
Advanced Medical Research Center
Advanced Medical Research Center（SENTANKEN）conducts basic studies aimed at overcoming cancer and lifestyle diseases and translational researches which applies the scientific finding to clinical medicine. It has three omics centers – genomics, proteomics, cellomics –and a biobank, collaborates within YCU and with other research institutions, and promote translational researches. AMRC is also involved in a number of R&D, working with the industry. Our goal is to make our research findings available to the society without delay.
Outline, Structure & Function of the Advanced Medical Research Center >
Outline, Structure & Function of the Advanced Medical Research Center >
RESEARCH > ADVANCED MEDICAL RESEARCH CENTER
Message from the Director
The Advanced Medical Research Center (SENTANKEN) of Yokohama City University(YCU) was established in 2006. The assignment of SENTANKEN is to facilitate advanced medical research associated with diseases such as cancer and lifestyle-related diseases. SENTANKEN is focused on basic researches in the field of genomics, proteomics and cellomics, as well as translational researches, which can fill the gap between basic and clinical researches, and promotes not only intramural collaboration but also between government, industry and academia.
Our goal is to make an attractive YCU that can contribute to the community by delivering the research outcomes of our basic and clinical researches promptly to the citizens of Yokohama and by connecting these activities for the revitalization of industries in Yokohama.
Our goal is to make an attractive YCU that can contribute to the community by delivering the research outcomes of our basic and clinical researches promptly to the citizens of Yokohama and by connecting these activities for the revitalization of industries in Yokohama.
Professor Atsushi Nakajima
Director, Advanced Medical Research Center
Departments & Divisions
Department of Research & Development
Developing new methods for prevention, diagnosis and treatment of socially significant illnesses such as cancer and lifestyle-related diseases.
Developing new methods for prevention, diagnosis and treatment of socially significant illnesses such as cancer and lifestyle-related diseases.
Department of Research Support & Coordination
The AMRC has seven research laboratories which can develop cutting-edge joint research activities at every level - from genomics to proteomics, to celllomics - and use secimens of excellent quality as medical resources.
The AMRC has seven research laboratories which can develop cutting-edge joint research activities at every level - from genomics to proteomics, to celllomics - and use secimens of excellent quality as medical resources.
Biobank Division
To ensure a timely supply of human tissue specimens to researchers for the purpose of Translational Research, the Biobank Division stores and manages tissue samples and clinical information provided by patients at the University Hospital.
To ensure a timely supply of human tissue specimens to researchers for the purpose of Translational Research, the Biobank Division stores and manages tissue samples and clinical information provided by patients at the University Hospital.
Research News
2023-05-17
Using a newly developed radiotracer, researchers find that Hebbian and homeostatic plasticity differentially regulate brain function in epilepsy
2022-03-31
Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) is a late-onset, slow-progressing multisystem neurodegenerative disorder. Biallelic AAGGG repeat expansion in RFC1 has been identified as causative of this disease, and repeat conformation heterogeneity (ACAGG repeat) was also recently implied.
To molecularly characterize this disease in Japanese patients with adult-onset ataxia, we accumulated and screened 212 candidate families by an integrated approach consisting of flanking PCR, repeat-primed PCR, Southern blotting and long-read sequencing using Sequel II, GridION or PromethION.
2022-03-30
Background Little is known about the population prevalence of antibodies against emerging immune escape variants of SARS-CoV-2.
Methods A population-based prevalence study was conducted in Yokohama City, the most populous municipality of Japan. Quantitative measurements of immunoglobulin G against SARS-CoV-2 spike protein (SP-IgG) and qualitative measurements of neutralization antibodies against the Omicron BA.1 and BA.2 variants were performed.
Contact info
sentan@yokohama-cu.ac.jp