YCU PR Office

2021-08-18

YCU Med Online Clinical Case Discussion with Shanghai Jiao Tong University and the University of Strasbourg

The YCU School of Medicine always sees the importance of offering our students world-standard medical education. As a part of our efforts, we have sent more than 10 faculty members in past years to the “PBL* Hawaii Style Workshop” organized by the University of Hawaii John A. Burns School of Medicine (JABSOM),
2021-07-01

Online PBL Session with the University of Hawaii John A. Burns School of Medicine

The YCU School of Medicine always sees the importance of offering our students world-standard medical education. As a part of our efforts, we have sent more than 10 faculty members in past years to the “PBL* Hawaii Style Workshop” organized by the University of Hawaii John A. Burns School of Medicine (JABSOM),
2021-05-17

Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing

Heterochromatin-related epigenetic mechanisms, such as DNA methylation, facilitate pairing of homologous chromosomes during the meiotic prophase of mammalian spermatogenesis. In pro-spermatogonia, de novo DNA methylation plays a key role in completing meiotic prophase and initiating meiotic division. However, the role of maintenance DNA methylation in the regulation of meiosis, especially in the adult, is not well understood. Here, we reveal that NP95 (also known as UHRF1) and DNMT1 – two essential proteins for maintenance DNA methylation – are co-expressed in spermatogonia and are necessary for meiosis in male germ cells.
2021-05-14

Refinement of the clinical variant interpretation framework by statistical evidence and machine learning

Although the American College of Medical Geneticsand Genomics/Association for Molecular Pathology (ACMG/AMP)guidelines for variant interpretation are used widely in clinical ge-netics, there is room for improvement of these knowledge-basedguidelines.