Fuel-Type Independent Parameterization of Volatile Organic Compound Emissions from Western US Wildfires

Volatile organic compounds (VOCs) emitted from biomass burning impact air quality and climate. Laboratory studies have shown that the variability in VOC speciation is largely driven by changes in combustion conditions and is only modestly impacted by fuel type.

ChemTSv2: Functional Molecular Design Using de novo Molecule Generator

Designing functional molecules is the prerogative of experts who have advanced knowledge and experience in their fields. To democratize automatic molecular design for both experts and nonexperts, we introduce a generic open-sourced framework, ChemTSv2, to design molecules based on a de novo molecule generator equipped with an easy-to-use interface.

Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos.

Introduction: Several healthy euploid births have been reported following the transfer of mosaic embryos, including both euploid and aneuploid blastomeres. This has been attributed to a reduced number of aneuploid cells, as previously reported in mice, but remains poorly explored in humans. We hypothesized that mitochondrial function, one of the most critical factors for embryonic development, can influence human post-implantation embryonic development, including a decrease of aneuploid cells in mosaic embryos.

Nuclear Magnetic Resonance Detection of Hydrogen Bond Network in a Proton Pump Rhodopsin RxR and Its Alteration during the Cyclic Photoreaction

Hydrogen bond formation and deformation are crucial for the structural construction and functional expression of biomolecules. However, direct observation of exchangeable hydrogens, especially for oxygen-bound hydrogens, relevant to hydrogen bonds is challenging for current structural analysis approaches.