Sentanken Archives - Page 13 of 35 - Yokohama City University

2023-03-15

Multiancestry genomic and transcriptomic analysis of gastric cancer

Gastric cancer is among the most common malignancies worldwide, characterized by geographical, epidemiological and histological heterogeneity. Here, we report an extensive, multiancestral landscape of driver events in gastric cancer, involving 1,335 cases. Seventy-seven significantly mutated genes (SMGs) were identified, including ARHGAP5 and TRIM49C. We also identified subtype-specific drivers, including PIGR and SOX9, which were enriched in the diffuse subtype of the disease. SMGs also varied according to Epstein–Barr virus infection status and ancestry.

2023-03-14

UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia

The prognosis of pediatric acute myeloid leukemia (AML) has improved via stratification therapy. However, relapse or death occurs in 30%–40% of cases. Novel genetic factors for pediatric AML need to be elucidated to improve prognosis.

2023-03-02

Tax-related Incentives and Expense Allocation in Nonprofit Organizations: Evidence from Japan.

The research problem This study investigates the relationship between the incentive of Japanese non-profit organizations to avoid losing their tax-exempt status and the extent of tax-motivated expense allocation.

2023-02-27

Prevalence and clinical features of long COVID from omicron infection in children and adults.

We read with interest the article reported by Elda Righi et al. about persistent symptoms after COVID-19.1 Following acute infection, various long-lasting symptoms such as fatigue, headache, cough, and muscle pain are described as “long COVID.”2 The World Health Organization (WHO) and the United States Centers for Disease Control and Prevention (CDC) have given incongruous definitions.3, 4 The prevalence of long COVID varies widely, partly because of variability in definitions, study design, sampling frame, vaccine status, comorbidity, and other factors.