News - Page 41 of 69 - Yokohama City University

2021-10-25

PRIMA: a rapid and cost-effective genotyping method to detect single-nucleotide differences using probe-induced heteroduplexes

Targeted mutagenesis by programmable site-specific nucleases like CRISPR typically produce 1-base pair (bp) insertion or deletion (indel) mutations. Although several methods have been developed to detect such 1-bp indels, each method has pros and cons in terms of cost and/or resolution. Heteroduplex mobility assay (HMA) is a traditional technique detecting small base pair differences but it has a limited resolution of mutation size and the band patterns are often complex.

2021-10-20

Identification of serum prognostic biomarkers of severe COVID‑19 using a quantitative proteomic approach

The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global health concerns. Since the etiopathogenesis of this illness is not fully characterized, the prognostic factors enabling treatment decisions have not been well documented. Accurately predicting the progression of the disease would aid in appropriate patient categorization and thus help determine the best treatment option.

2021-10-16

Event Report: The 12th IACSC International Symposium/General Assembly

The 11th International Academic Consortium for Sustainable Cities (IACSC) International Symposium/General Assembly was held on November 14th, 2020, online and at Vietnam National University in Vietnam.

2021-10-14

Deformation of microtubules regulates translocation dynamics of kinesin

Microtubules, the most rigid components of the cytoskeleton, can be key transduction elements between external forces and the cellular environment. Mechanical forces induce microtubule deformation, which is presumed to be critical for the mechanoregulation of cellular events.