2023-02-09

Utility of Commercial High Resolution Satellite Imagery for Monitoring General Flowering in Sarawak, Borneo

General flowering (GF), irregular synchronous mass flowering of multiple tree species across multiple families, is a unique biological phenomenon of the mixed lowland dipterocarp forest in Southeast Asia. Characterizing the spatial extent and temporal dynamics of GF is essential for an improved understanding of climate–vegetation interactions and the potential climate change impact on this species-rich rainforest.
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2023-02-07

Cardiovascular and kidney outcomes of combination therapy with sodium-glucose cotransporter-2 inhibitors and mineralocorticoid receptor antagonists in patients with type 2 diabetes and chronic kidney disease: A systematic review and network meta-analysis

Aims Both sodium-glucose cotransporter-2 (SGLT-2) inhibitors and mineralocorticoid receptor antagonists (MRAs) have been shown to reduce cardiovascular (CV) event in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). However, little evidence pertains to the benefits of their combined use.
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2023-02-07

Effects of sodium-glucose cotransporter 2 inhibitors, mineralocorticoid receptor antagonists, and their combination on albuminuria in diabetic patients
Azushima, Hiromichi Wakui, Kouichi Tamura

Aims Diabetes mellitus (DM) is the leading cause of chronic kidney disease. Albuminuria is associated with an increased risk of cardiovascular mortality. Sodium-glucose cotransporter 2 inhibitors (SGLT2-Is) and mineralocorticoid receptor antagonists (MRAs) protect against albuminuria; however, their combined effects on albuminuria are unclear. We performed a network meta-analysis to investigate the effects of SGLT2-Is, MRAs and their combination on albuminuria in type 2 DM.
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2023-01-31

Transform in seconds, ready for fertilization.

Maruyama and his colleagues including Project Assistant Professor Naoya Sugi and Rie Izumi developed new live-imaging system and captured the moment of sperm cell maturation prior to double fertilization in a model plant Arabidopsis thaliana.
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