News - Page 25 of 80 - Yokohama City University

2023-03-15

Multiancestry genomic and transcriptomic analysis of gastric cancer

Gastric cancer is among the most common malignancies worldwide, characterized by geographical, epidemiological and histological heterogeneity. Here, we report an extensive, multiancestral landscape of driver events in gastric cancer, involving 1,335 cases. Seventy-seven significantly mutated genes (SMGs) were identified, including ARHGAP5 and TRIM49C. We also identified subtype-specific drivers, including PIGR and SOX9, which were enriched in the diffuse subtype of the disease. SMGs also varied according to Epstein–Barr virus infection status and ancestry.

2023-03-14

UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia

The prognosis of pediatric acute myeloid leukemia (AML) has improved via stratification therapy. However, relapse or death occurs in 30%–40% of cases. Novel genetic factors for pediatric AML need to be elucidated to improve prognosis.

2023-03-02

Tax-related Incentives and Expense Allocation in Nonprofit Organizations: Evidence from Japan.

The research problem This study investigates the relationship between the incentive of Japanese non-profit organizations to avoid losing their tax-exempt status and the extent of tax-motivated expense allocation.

2023-03-02

Elucidation of the impacts of the standard for the ratio of expenses for non-taxable activity on the expense allocation behavior of Japanese nonprofit organizations

Associate Professor Makoto Kuroki of the Yokohama City University Graduate School of International Management and Hiroki Natsuyoshi have become the first researchers in Japan to elucidate the impacts of the existence of a standard for the ratio of expenses for non-taxable activities for public interest incorporated associations