Health-Med

2022-08-05

Structure of SARS-CoV-2 membrane protein essential for virus assembly

The coronavirus membrane protein (M) is the most abundant viral structural protein and plays a central role in virus assembly and morphogenesis. However, the process of M protein-driven virus assembly are largely unknown. Here, we report the cryo-electron microscopy structure of the SARS-CoV-2 M protein in two different conformations.
2022-08-01

An autopsy case of COVID-19-like acute respiratory distress syndrome after mRNA-1273 SARS-CoV-2 vaccination.

Highlights •An old woman developed interstitial pneumonia after mRNA-1273 vaccination. •The patient's symptoms, laboratory findings, and images were similar to those of COVID-19. •Serological and pathological tests were useful in diagnosing vaccine-induced acute respiratory distress syndrome. •Serum level of antibodies against spike protein was extremely high.
2022-07-14

A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron

We are amid the historic coronavirus infectious disease 2019 (COVID-19) pandemic. Imbalances in the accessibility of vaccines, medicines, and diagnostics among countries, regions, and populations, and those in war crises, have been problematic.
2022-07-12

Impact of COVID-19 pandemic on epilepsy care in Japan: A national-level multicenter retrospective cohort study.

Objective The impact of the coronavirus disease 2019 (COVID-19) pandemic on epilepsy care across Japan was investigated by conducting a multicenter retrospective cohort study.