YCU PR Office, Author at Yokohama City University

2019-07-11

South Africa before 1994, after 1994 and Collaboration with Japan

H.E. Mr. Lulama Smuts Ngonyama, the Ambassador Extraordinary and Plenipotentiary of the Republic of South Africa, delivered a lecture titled “South Africa before 1994, after 1994 and Collaboration with Japan” on 11 July 2019. Professor Eiichi Yoshida, who is an expert in African Studies, served as a moderator.

2019-06-28

Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice

The interaction between atherosclerosis and commensal microbes through leaky gut syndrome (LGS), which is characterized by impaired intestinal permeability and the introduction of undesired pathogens into the body, has not been fully elucidated. Our aim was to investigate the potential role of a ClC-2 chloride channel activator, lubiprostone, which is reported to have beneficial effects on LGS, in the development of atherosclerosis in apolipoprotein E–deficient (ApoE-/-) mice.

2019-06-10

Comprehensive analysis of coding variants highlights genetic complexity in developmental and epileptic encephalopathy

Although there are many known Mendelian genes linked to epileptic or developmental and epileptic encephalopathy (EE/DEE), its genetic architecture is not fully explained. Here, we address this incompleteness by analyzing exomes of 743 EE/DEE cases and 2366 controls. We observe that damaging ultra-rare variants (dURVs) unique to an individual are significantly overrepresented in EE/DEE, both in known EE/DEE genes and the other non-EE/DEE genes.

2019-06-09

Okurayama International Forum 2019

On June 29th, 2019, the ninth Okurayama International Student Forum was successfully held at Okurayama Memorial Hall in Yokohama. About 30 Japanese students from Yokohama City University, Tokyo Institute of Technology and Keio University had a cordial and friendly communication with students from Harvard University.