YCU PR Office, Author at Yokohama City University

2020-02-28

[COVID-19] Important Notice for Novel Coronavirus Infection Prevention and Control

The World Health Organization declared Public Health Emergency of International Concern for the Novel Coronavirus infection on January 30th, 2020. As human-to-human infection is also reported in Japan, all students, faculty and staff should take infection prevention measures.

2020-02-26

Accurate identification of dimers from α‐pinene oxidation using high‐resolution collision‐induced dissociation mass spectrometry

Interest in mass spectrometry of highly oxidized dimers from α‐pinene oxidation has increased in the atmospheric chemistry field. Here, we apply high‐resolution collision‐induced dissociation mass spectrometry (HR‐CID‐MS) with an atmospheric pressure ionization source to investigate in detail how α‐pinene‐derived dimers are detected and identified by MS.

2020-02-13

Loss of p53 drives neuron reprogramming in head and neck cancer

The solid tumour microenvironment includes nerve fibres that arise from the peripheral nervous system. Recent work indicates that newly formed adrenergic nerve fibres promote tumour growth, but the origin of these nerves and the mechanism of their inception are unknown. Here, by comparing the transcriptomes of cancer-associated trigeminal sensory neurons with those of endogenous neurons in mouse models of oral cancer, we identified an adrenergic differentiation signature.

2020-01-29

Compound lights up brain receptors in PET scans

A radiotracer specifically binds to a major class of brain receptors when injected into living rats and humans, lighting them up in PET scans. The compound, called [11C]K-2, was designed and tested by a large team of scientists in Japan, led by Professor Takuya Takahashi of the department of physiology at Yokohama City University Graduate School of Medicine. It shows promise for diagnosing and treating epilepsy and for improving understanding of psychiatric diseases. Details of the team’s findings were published in the journal Nature Medicine.