横浜市立大学 医学部 消化器内科学教室

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Zhang Y先生の論文が掲載されました.

Zhang Y先生の論文が掲載されました.

Contrast Agents for Hepatocellular Carcinoma Imaging: Value and Progression. Front Oncol. 2022 Jun 2;12:921667.

本論文は中国からの日本財団助成の私費留学生の張瑛医師がfirst authorの肝臓画像の造影剤についてのreview articleです.(沼田)

The present review article introduced several intravenous contrast media (CMs) for liver imaging according to the biobehavioral features, like inside distribution and metabolization pathway, which is a brief summarized navigating map of CMs that are commonly used in the clinic.  Beyond the classical wash-in and wash-out characteristics provided by classical blood pool contrast agents, an additional Kupffer phase could be provided by Sonazoid, a micrometer-scaled microbubble with inert gas enveloped inside as an ultrasound contrast agent (UCA).  Likewise, by means of extracellular contrast agents, reticuloendothelial system endocytosis and hepatocyte-specific uptake agents bring more informative images to diagnostic MRI.  Moreover, the molecular imaging agents, including immune molecular probes, stimulus-responsive/microenvironment dependent contrast agents, and scale-dependent particles have drawn a blueprint for future liver imaging.(Zhang Y)