横浜市立大学眼科先進医療学講座

教授挨拶

研究業績

2021年 2020年 2019年 2018年
2017年 2016年 2015年 2014年
2013年 2012年以前

英文原著

2021年
1. Su G, Zhong Z, Zhou Q, Du L, Ye Z, Li F, Zhuang W, Wang C, Liang L, Ji Y, Cao Q, Wang Q, Chang R, Tan H, Yi S, Li Y, Feng X, Liao W, Zhang W, Shu J, Tan S, Xu J, Pan S, Li H, Shi J, Chen Z, Zhu Y, Ye X, Tan X, Zhang J, Liu Z, Huang F, Yuan G, Pang T, Liu Y, Ding J, Gao Y, Zhang M, Chi W, Liu X, Wang Y, Chen L, Meguro A, Takeuchi M, Mizuki N, Ohno S, Zuo X, Kijlstra A, Yang P. A genome-wide association study in Chinese identifies novel risk loci for Behcet's uveitis. Arthritis Rheumatol. 2021 Oct 15. doi: 10.1002/art.41998. [Online ahead of print]
2. Ida Y, Takeuchi M, Ishihara M, Shibuya E, Yamane T, Hasumi Y, Kawano S, Kimura I, Mizuki N. An open-label, prospective, single-arm study of switching from infliximab to cyclosporine for refractory uveitis in patients with Behçet's disease in long-term remission. Jpn J Ophthalmol. 2021 Sep 29. doi: 10.1007/s10384-021-00872-2. [Online ahead of print]
3. Teshigawara T, Meguro A, Mizuki N. Relationship Between Postoperative Intraocular Lens Shift and Postoperative Refraction Change in Cataract Surgery Using Three Different Types of Intraocular Lenses. Ophthalmol Ther. 2021 Sep 3. doi: 10.1007/s40123-021-00390-x. [Online ahead of print]
4. Teshigawara T, Meguro A, Mizuki N. Effects of Rebamipide on Differences in Power and Axis of Corneal Astigmatism Between Two Intra-patient Keratometric Measurements in Dry Eyes. Ophthalmol Ther. 2021 Jul 22. doi: 10.1007/s40123-021-00368-9. [Online ahead of print]
5. Hirahara L, Kirino Y, Soejima Y, Takeno M, Takase-Minegishi K, Yoshimi R, Takeuchi M, Mizuki N, Nakajima H. Efficacy and safety of apremilast for 3 months in Behçet's disease: A prospective observational study. Mod Rheumatol. 2021;31(4):856-861. doi: 10.1080/14397595.2020.1830504.
6. Nagano A, Takeuchi M, Horita N, Teshigawara T, Kawagoe T, Mizuki Y, Meguro A, Nakano H, Kirino Y, Takase-Minegishi K, Yoshimi R, Kurosawa M, Fukumoto T, Takeno M, Kaneko T, Mizuki N. Behçet's disease and activities of daily living. Rheumatology (Oxford). 2021 Jun 19:keab499. doi: 10.1093/rheumatology/keab499. [Online ahead of print]
7. Fukuda M, Nakamura J, Ito S, Kawazoe K, Miyanaga Y, Teshigawara T, Okuda K, Mizuki N, Shimada M. Vaccination inhibits the human adenoviral transduction in a mouse keratoconjunctivitis model. Vaccine. 2021;39(26):3498-3508. doi: 10.1016/j.vaccine.2021.05.010.
8. Ito S, Nakamura J, Fukuta M, Ura T, Teshigawara T, Fukushima J, Mizuki N, Okuda K, Shimada M. Prophylactic and therapeutic vaccine against Pseudomonas aeruginosa keratitis using bacterial membrane vesicles. Vaccine. 2021;39(23):3152-3160. doi: 10.1016/j.vaccine.2021.04.035.
9. Ishii M, Horita N, Takeuchi M, Matsumoto H, Ebina-Shibuya R, Hara Y, Kobayashi N, Mizuki N, Kaneko T. Inhaled Corticosteroid and Secondary Glaucoma: A Meta-analysis of 18 Studies. Allergy Asthma Immunol Res. 2021;13(3):435-449. doi: 10.4168/aair.2021.13.3.435.
10. Kokubo K, Katori N, Hayashi K, Fujii A, Kitamura S, Haga S, Maeda C, Mizuki N, Maegawa J. Comparison of postoperative recurrence rates between levator aponeurosis advancement and external Müller's muscle tucking for acquired blepharoptosis. J Plast Reconstr Aesthet Surg. 2021 Apr 24:S1748-6815(21)00190-X. doi: 10.1016/j.bjps.2021.03.086. [Online ahead of print]
11. Kobayashi Y, Tomizawa SI, Ono M, Kuroha K, Minamizawa K, Natsume K, Dizdarević S, Dočkal I, Tanaka H, Kawagoe T, Seki M, Suzuki Y, Ogonuki N, Inoue K, Matoba S, Anastassiadis K, Mizuki N, Ogura A, Ohbo K. Tsga8 is required for spermatid morphogenesis and male fertility in mice. Development. 2021;148(8):dev196212. doi: 10.1242/dev.196212.
12. Takeuchi M, Mizuki N, Ohno S. Pathogenesis of Non-Infectious Uveitis Elucidated by Recent Genetic Findings. Front Immunol. 2021;12:640473. doi: 10.3389/fimmu.2021.640473.
13. Zhong Z, Su G, Zhou Q, Meguro A, Takeuchi M, Mizuki N, Ohno S, Liao W, Feng X, Ding J, Gao Y, Chi W, Zhang M, Zuo X, Yang P. Tuberculosis Exposure With Risk of Behçet Disease Among Patients With Uveitis. JAMA Ophthalmol. 2021;139(4):415-422. doi: 10.1001/jamaophthalmol.2020.6985.
14. Soejima Y, Kirino Y, Takeno M, Kurosawa M, Takeuchi M, Yoshimi R, Sugiyama Y, Ohno S, Asami Y, Sekiguchi A, Igarashi T, Nagaoka S, Ishigatsubo Y, Nakajima H, Mizuki N. Changes in the proportion of clinical clusters contribute to the phenotypic evolution of Behçet's disease in Japan. Arthritis Res Ther. 2021;23(1):49. doi: 10.1186/s13075-020-02406-6.
15. Ura T, Yamashita A, Mizuki N, Okuda K, Shimada M. New vaccine production platforms used in developing SARS-CoV-2 vaccine candidates. Vaccine. 2021;39(2):197-201. doi: 10.1016/j.vaccine.2020.11.054.
16. Kato H, Takeuchi M, Horita N, Ishido T, Mizuki R, Kawagoe T, Shibuya E, Yuda K, Ishido M, Mizuki Y, Hayashi T, Meguro A, Kirino Y, Minegishi K, Nakano H, Yoshimi R, Kurosawa M, Fukumoto T, Takeno M, Hotta K, Kaneko T, Mizuki N. HLA-A26 is a Risk Factor for Behçet's Disease Ocular Lesions. Mod Rheumatol. 2021;31(1):214-218. doi: 10.1080/14397595.2019.1705538.
17. Polouliakh N, Ludwig V, Meguro A, Kawagoe T, Heeb O, Mizuki N. Corrigendum: Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast. Front Physiol. 2021;12:659813. doi: 10.3389/fphys.2021.659813.
2020年
18. Mahmoudi M, Aslani S, Meguro A, Akhtari M, Fatahi Y, Mizuki N, Shahram F. A comprehensive overview on the genetics of Behçet's disease. Int Rev Immunol. 2020 Dec 1:1-64. doi: 10.1080/08830185.2020.1851372. [Online ahead of print]
19. Meguro A, Yamane T, Takeuchi M, Miyake M, Qiao F, Zhao W, Wang IJ, Mizuki Y, Yamada N, Nomura N, Tsujikawa A, Matsuda F, Hosoda Y, Saw SM, Cheng CY, Tsai TH, Yoshida M, Iijima Y, Teshigawara T, Okada E, Ota M, Inoko H, Mizuki N. Genome-wide association study in Asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis. Ophthalmology. 2020;127(12):1612-1624. doi: 10.1016/j.ophtha.2020.05.014.
20. Teshigawara T, Meguro A, Mizuki N. Suction Break During Femtosecond Laser-Assisted Cataract Surgery and Misplaced Laser Beam Delivery to the Corneal Layers. Int Med Case Rep J. 2020;13:643-650. doi: 10.2147/IMCRJ.S280403.
21. Polouliakh N, Ludwig V, Meguro A, Kawagoe T, Heeb O, Mizuki N. Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast. Front Physiol. 2020;11:586843. doi: 10.3389/fphys.2020.586843.
22. Teshigawara T, Meguro A, Mizuki N. Nd:YAG Laser Accidentally Hitting the Corneal Layers During Treatment of Posterior Capsule Opacification After Cataract Surgery and Its Postoperative Process. Int Med Case Rep J. 2020;13:449-453. doi: 10.2147/IMCRJ.S271669.
23. Meguro A, Ishihara M, Petrek M, Yamamoto K, Takeuchi M, Mrazek F, Kolek V, Benicka A, Yamane T, Shibuya E, Yoshino A, Isomoto A, Ota M, Yatsu K, Shijubo N, Nagai S, Yamaguchi E, Yamaguchi T, Namba K, Kaburaki T, Takase H, Morimoto SI, Hori J, Kono K, Goto H, Suda T, Ikushima S, Ando Y, Takenaka S, Takeuchi M, Yuasa T, Sugisaki K, Ohguro N, Hiraoka M, Kitaichi N, Sugiyama Y, Horita N, Asukata Y, Kawagoe T, Kimura I, Ishido M, Inoko H, Mochizuki M, Ohno S, Bahram S, Remmers EF, Kastner DL, Mizuki N. Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis. Commun Biol. 2020;3(1):465. doi: 10.1038/s42003-020-01185-9.
24. Takase H, Goto H, Namba K, Mizuki N, Okada AA, Ohguro N, Sonoda KH, Tomita M, Keino H, Kezuka T, Kubono R, Mizuuchi K, Shibuya E, Takahashi H, Yanai R, Mochizuki M. Clinical Characteristics, Management, and Factors Associated with Poor Visual Prognosis of Acute Retinal Necrosis. Ocul Immunol Inflamm. 2020 Sep 18:1-6. doi: 10.1080/09273948.2020.1789179. [Online ahead of print]
25. Teshigawara T, Meguro A, Mizuki N. A Comparison Between Monofocal and Multifocal Intraocular Lenses in the Influence of Pupil Dilation on Target Postoperative Refraction. Asia Pac J Ophthalmol (Phila). 2020;9(5):420-425. doi: 10.1097/APO.0000000000000310.
26. Shimada M, Yamashita A, Saito M, Ichino M, Kinjo T, Mizuki N, Klinman DM, Okuda K. The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation. Sci Rep. 2020;10(1):14195. doi: 10.1038/s41598-020-71134-3.
27. Ishihara M, Meguro A, Ishido M, Takeuchi M, Shibuya E, Mizuki N. Usefulness of Combined Measurement of Serum Soluble IL-2R and Angiotensin-Converting Enzyme in the Detection of Uveitis Associated with Japanese Sarcoidosis. Clin Ophthalmol. 2020;14:2311-2317. doi: 10.2147/OPTH.S264595.
28. Hosoda Y, Miyake M, Meguro A, Tabara Y, Iwai S, Ueda-Arakawa N, Nakano E, Mori Y, Yoshikawa M, Nakanishi H, Khor CC, Saw SM, Yamada R, Matsuda F, Cheng CY, Mizuki N, Tsujikawa A, Yamashiro K; Nagahama Study Group. Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson. Commun Biol. 2020;3(1):410. doi: 10.1038/s42003-020-01137-3.
29. Teshigawara T, Meguro A, Mizuki N. Influence of pupil dilation on the Barrett universal II (new generation), Haigis (4th generation), and SRK/T (3rd generation) intraocular lens calculation formulas: a retrospective study. BMC Ophthalmol. 2020;20(1):299. doi: 10.1186/s12886-020-01571-1.
30. Watanabe K, Tanida S, Inoue N, Kunisaki R, Kobayashi K, Nagahori M, Arai K, Uchino M, Koganei K, Kobayashi T, Takeno M, Ueno F, Matsumoto T, Mizuki N, Suzuki Y, Hisamatsu T. Evidence-based diagnosis and clinical practice guidelines for intestinal Behçet's disease 2020 edited by Intractable Diseases, the Health and Labour Sciences Research Grants. J Gastroenterol. 2020;55(7):679-700. doi: 10.1007/s00535-020-01690-y.
31. Mizuki Y, Horita N, Horie Y, Takeuchi M, Ishido T, Mizuki R, Kawagoe T, Shibuya E, Yuda K, Ishido M, Minegishi K, Yoshimi R, Kirino Y, Kato S, Arimoto J, Fukumoto T, Kurosawa M, Kitaichi N, Takeno M, Kaneko T, Mizuki N. The influence of HLA-B51 on clinical manifestations among Japanese patients with Behçet's disease: A nationwide survey. Mod Rheumatol. 2020;30(4):708-714. doi: 10.1080/14397595.2019.1649103.
32. Sakono T, Meguro A, Takeuchi M, Yamane T, Teshigawara T, Kitaichi N, Horie Y, Namba K, Ohno S, Nakao K, Sakamoto T, Sakai T, Nakano T, Keino H, Okada AA, Takeda A, Ito T, Mashimo H, Ohguro N, Oono S, Enaida H, Okinami S, Horita N, Ota M, Mizuki N. Variants in IL23R-C1orf141 and ADO-ZNF365-EGR2 are associated with susceptibility to Vogt-Koyanagi-Harada disease in Japanese population. PLoS One. 2020;15(5):e0233464. doi: 10.1371/journal.pone.0233464.
33. Nakamura K, Iwata Y, Asai J, Kawakami T, Tsunemi Y, Takeuchi M, Mizuki N, Kaneko F; Members of the Consensus Conference on Treatment of Skin and Mucosal Lesions (Committee of Guideline for the Diagnosis and Treatment of Mucocutaneous Lesions of Behçet's disease). Guidelines for the treatment of skin and mucosal lesions in Behçet's disease: A secondary publication. J Dermatol. 2020;47(3):223-235. doi: 10.1111/1346-8138.15207.
34. Kobashigawa Y, Shimizu T, Hayashi T, Kobashigawa H, Yuda K, Mizuki N, Yamada N, Kato N. Iris Posterior Synechiae After Descemet Membrane Endothelial Keratoplasty in Asian Eyes: Prevention and Management of Posterior Synechiae. Eye Contact Lens. 2020;46(2):116-120. doi: 10.1097/ICL.0000000000000616.
35. Riahi P, Kazemnejad A, Mostafaei S, Meguro A, Mizuki N, Ashraf-Ganjouei A, Javinani A, Faezi ST, Shahram F, Mahmoudi M. ERAP1 polymorphisms interactions and their association with Behçet's disease susceptibly: Application of Model-Based Multifactor Dimension Reduction Algorithm (MB-MDR). PLoS One. 2020;15(2):e0227997. doi: 10.1371/journal.pone.0227997.
36. Mitsuhashi M, Yoshimi R, Kishimoto D, Hidekawa C, Iizuka Y, Sakurai N, Kamiyama R, Kirino Y, Kondo Y, Mizuki N, Nakajima H. Refractory optic perineuritis related to granulomatosis with polyangiitis treated with intensive immunosuppressive therapy combined with plasma exchange. Mod Rheumatol Case Rep. 2020;4(1):84-89. doi: 10.1080/24725625.2019.1649857.
2019年
37. Hosoda Y, Miyake M, Schellevis RL, Boon CJF, Hoyng CB, Miki A, Meguro A, Sakurada Y, Yoneyama S, Takasago Y, Hata M, Muraoka Y, Nakanishi H, Oishi A, Ooto S, Tamura H, Uji A, Miyata M, Takahashi A, Ueda-Arakawa N, Tajima A, Sato T, Mizuki N, Shiragami C, Iida T, Khor CC, Wong TY, Yamada R, Honda S, de Jong EK, Hollander AID, Matsuda F, Yamashiro K, Tsujikawa A. Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy. Commun Biol. 2019;2:468. doi: 10.1038/s42003-019-0712-z.
38. Okazaki S, Meguro A, Ideta R, Takeuchi M, Yonemoto J, Teshigawara T, Yamane T, Okada E, Ideta H, Mizuki N. Common variants in the COL2A1 gene are associated with lattice degeneration of the retina in a Japanese population. Mol Vis. 2019;25:843-850.
39. Suzuki T, Horita N, Takeuchi M, Ishido T, Mizuki Y, Mizuki R, Kawagoe T, Shibuya E, Yuta K, Yamane T, Hayashi T, Meguro A, Ishido M, Minegishi K, Yoshimi R, Kirino Y, Kato S, Arimoto J, Fukumoto T, Ishigatsubo Y, Kurosawa M, Takeno M, Kaneko T, Mizuki N. Clinical features of early-stage possible Behçet's disease patients with a variant-type major organ involvement in Japan. Mod Rheumatol. 2019;29(4):640-646. doi: 10.1080/14397595.2018.1494501.
40. Tase S, Shimizu T, Hayashi T, Tabuchi H, Niimi K, Mizuki N, Kato N. Descemet's membrane endothelial keratoplasty for pseudoexfoliation syndrome: a case series. BMC Ophthalmol. 2019;19(1):119. doi: 10.1186/s12886-019-1130-1.
41. Teshigawara T, Meguro A, Sanjo S, Hata S, Mizuki N. The advantages of femtosecond laser-assisted cataract surgery for zonulopathy. Int Med Case Rep J. 2019;12:109-116. doi: 10.2147/IMCRJ.S189367.
42. Nakamura J, Meguro A, Ishii G, Mihara T, Takeuchi M, Mizuki Y, Yuda K, Yamane T, Kawagoe T, Ota M, Mizuki N. The association analysis between HLA-A*26 and Behçet's disease. Sci Rep. 2019;9(1):4426. doi: 10.1038/s41598-019-40824-y.
43. Takeuchi M, Kanda T, Kaburaki T, Tanaka R, Namba K, Kamoi K, Maruyama K, Shibuya E, Mizuki N. Real-world evidence of treatment for relapse of noninfectious uveitis in tertiary centers in Japan: A multicenter study. Medicine (Baltimore). 2019;98(9):e14668. doi: 10.1097/MD.0000000000014668.
44. Suwa A, Horita N, Ishido T, Takeuchi M, Kawagoe T, Shibuya E, Yamane T, Hayashi T, Meguro A, Ishido M, Minegishi K, Yoshimi R, Kirino Y, Kato S, Arimoto J, Fukumoto T, Ishigatsubo Y, Kurosawa M, Kaneko T, Takeno M, Mizuki N. The ocular involvement did not accompany with the genital ulcer or the gastrointestinal symptoms at the early stage of Behçet's disease. Mod Rheumatol. 2019;29(2):357-362. doi: 10.1080/14397595.2018.1457424.
45. Ohno T, Meguro A, Takeuchi M, Yamane T, Teshigawara T, Kitaichi N, Horie Y, Namba K, Ohno S, Nakao K, Sakamoto T, Sakai T, Nakano T, Keino H, Okada AA, Takeda A, Fukuhara T, Mashimo H, Ohguro N, Oono S, Enaida H, Okinami S, Mizuki N. Association Study of ARMC9 Gene Variants with Vogt-Koyanagi-Harada Disease in Japanese Patients. Ocul Immunol Inflamm. 2019;27(5):699-705. doi: 10.1080/09273948.2018.1523438.
46. Goto H, Zako M, Namba K, Hashida N, Kaburaki T, Miyazaki M, Sonoda KH, Abe T, Mizuki N, Kamoi K, Brézin AP, Dick AD, Jaffe GJ, Nguyen QD, Inomata N, Kwatra NV, Camez A, Song AP, Kron M, Tari S, Ohno S. Adalimumab in Active and Inactive, Non-Infectious Uveitis: Global Results from the VISUAL I and VISUAL II Trials. Ocul Immunol Inflamm. 2019;27(1):40-50. doi: 10.1080/09273948.2018.1491605.
2018年
47. Mahmoudi M, Ashraf-Ganjouei A, Javinani A, Shahram F, Meguro A, Mizuki N, Ahmadzadeh N, Jafarinejad-Farsangi S, Mostafaei S, Kavosi H, Faezi ST, Akhlaghi M, Davatchi F. Epistatic Interaction of ERAP1 and HLA-B*51 in Iranian Patients with Behçet's Disease. Sci Rep. 2018;8(1):17612. doi: 10.1038/s41598-018-35700-0.
48. Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A, Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F. Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. Proc Natl Acad Sci U S A. 2018;115(51):13045-13050. doi: 10.1073/pnas.1808850115.
49. Teshigawara T, Meguro A, Yabuki K, Hata S, Mizuki N. Visual performance of the intraindividual implantation of a trifocal intraocular lens in the bag and a +4.0 D bifocal intraocular lens in the sulcus with optic capture created by femtosecond laser-assisted cataract surgery. Int Med Case Rep J. 2018;11:251-257. doi: 10.2147/IMCRJ.S176095.
50. Teshigawara T, Meguro A, Mizuki N. Influence of pupil dilation on predicted postoperative refraction and recommended IOL to obtain target postoperative refraction calculated by using third- and fourth-generation calculation formulas. Clin Ophthalmol. 2018;12:1913-1919. doi: 10.2147/OPTH.S172846
51. Ohno T, Ishihara M, Shibuya E, Mizuki N. Sarcoid uveitis in a patient with multiple neurological lesions: a case report and review of the literature. J Med Case Rep. 2018;12(1):307. doi: 10.1186/s13256-018-1842-5.
52. Shimizu T, Hayashi T, Yuda K, Takahashi H, Oyakawa I, Yamazaki K, Mizuki N, Kato N. Short Axial Length and Iris Damage Are Associated With Iris Posterior Synechiae After Descemet Membrane Endothelial Keratoplasty in Asian Eyes. Cornea. 2018;37(11):1355-1359. doi: 10.1097/ICO.0000000000001698.
53. Hayashi T, Oyakawa I, Matsuzawa A, Yuda K, Shimizu T, Tsuchiya A, Mizuki N, Kato N. Descemet membrane endothelial keratoplasty using ophthalmic viscoelastic devices for eyes with laser iridotomy-induced corneal endothelial decompensation: Analysis of 11 eyes. Medicine (Baltimore). 2018;97(26):e11245. doi: 10.1097/MD.0000000000011245.
54. Ishihara M, Shibuya E, Tanaka S, Mizuki N. Diagnostic and therapeutic evaluation of multiple choroidal granulomas in a patient with confirmed sarcoidosis using enhanced depth imaging optical coherence tomography. Int Ophthalmol. 2018;38(6):2603-2608. doi: 10.1007/s10792-017-0720-2.
55. Kinota F, Droma Y, Kobayashi N, Horiuchi T, Kitaguchi Y, Yasuo M, Ota M, Hanaoka M. The Contribution of Genetic Variants of the Peroxisome Proliferator-Activated Receptor-Alpha Gene to High-Altitude Hypoxia Adaptation in Sherpa Highlanders. High Alt Med Biol. 2018 Nov 22. doi: 10.1089/ham.2018.0052. [Online ahead of print]
56. Umemura T, Yamazaki T, Joshita S, Sugiura A, Fujimori N, Matsumoto A, Ota M, Tanaka E. Quantitative analysis of serum chemokines associated with treatment failure of direct-acting antivirals in chronic hepatitis C. Cytokine. 2018;111:357-363. doi: 10.1016/j.cyto.2018.10.004.
57. Yamazaki T, Umemura T, Joshita S, Yoshizawa K, Tanaka E, Ota M. A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis. Sci Rep. 2018;8(1):11924. doi: 10.1038/s41598-018-30406-9
58. Joshita S, Umemura T, Usami Y, Yamashita Y, Norman GL, Sugiura A, Yamazaki T, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Yoshizawa K, Ota M, Tanaka E. Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis. Sci Rep. 2018;8(1):8159. doi: 10.1038/s41598-018-26531-0.
59. Saito H, Umemura T, Joshita S, Yamazaki T, Fujimori N, Kimura T, Komatsu M, Matsumoto A, Tanaka E, Ota M. KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients. Oncotarget. 2018; 9(28):19650-19661. doi: 10.18632/oncotarget.24752.
60. Saito H, Hirayama A, Umemura T, Joshita S, Mukawa K, Suga T, Tanaka E, Ota M. Association between KIR-HLA combination and ulcerative colitis and Crohn's disease in a Japanese population. PLoS One. 2018;13(4):e0195778. doi: 10.1371/ journal.pone.0195778.
61. Yamazaki T, Joshita S, Umemura T, Usami Y, Sugiura A, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Ota M, Tanaka E. Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C. PLoS One. 2018;13(4):e0195632. doi: 10.1371/journal.pone.0195632.
62. Joshita S, Umemura T, Tanaka E, Ota M. Genetics and epigenetics in the pathogenesis of primary biliary cholangitis. Clin J Gastroenterol. 2018;11(1):11-18. doi: 10.1007/s12328-017-0799-z.
63. Joshita S, Ichikawa Y, Umemura T, Usami Y, Sugiura A, Shibata S, Yamazaki T, Fujimori N, Komatsu M, Matsumoto A, Igarashi K, Ota M, Tanaka E. Serum Autotaxin Is a Useful Liver Fibrosis Marker in Patients with Chronic Hepatitis B Virus Infection. Hepatol Res. 2018;48(4):275-285. doi: 10.1111/hepr.12997.
2017年
64. Kawagoe T, Ota M, Meguro A, Takeuchi M, Yamane T, Shimazaki H, Takeuchi M, Okada E, Teshigawara T, Mizuki N. Associations between CRYBA4 gene variants and high myopia in a Japanese population. Clin Ophthalmol. 2017;11:2151-2156. doi: 10.2147/OPTH.S146038.
65. Ishido T, Horita N, Takeuchi M, Kawagoe T, Shibuya E, Yamane T, Hayashi T, Meguro A, Ishido M, Minegishi K, Yoshimi R, Kirino Y, Kato S, Arimoto J, Ishigatsubo Y, Takeno M, Kurosawa M, Kaneko T, Mizuki N. Clinical manifestations of Behçet's disease depending on sex and age: results from Japanese nationwide registration. Rheumatology (Oxford). 2017;56(11):1918-1927. doi: 10.1093/rheumatology/kex285.
66. Yamazoe K, Meguro A, Takeuchi M, Shibuya E, Ohno S, Mizuki N. Comprehensive analysis of the association between UBAC2 polymorphisms and Behçet's disease in a Japanese population. Sci Rep. 2017;7(1):742. doi: 10.1038/s41598-017-00877-3.
67. Takeuchi M, Mizuki N, Meguro A, Ombrello MJ, Kirino Y, Satorius C, Le J, Blake M, Erer B, Kawagoe T, Ustek D, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Sousa I, Davatchi F, Francisco V, Shahram F, Abdollahi BS, Nadji A, Shafiee NM, Ghaderibarmi F, Ohno S, Ueda A, Ishigatsubo Y, Gadina M, Oliveira SA, Gül A, Kastner DL, Remmers EF. Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility. Nat Genet. 2017;49(3):438-443. doi: 10.1038/ng.3786.
68. Horie Y, Meguro A, Ohta T, Lee EB, Namba K, Mizuuchi K, Iwata D, Mizuki N, Ota M, Inoko H, Ishida S, Ohno S, Kitaichi N. HLA-B51 Carriers are Susceptible to Ocular Symptoms of Behçet Disease and the Association between the Two Becomes Stronger Towards the East Along the Silk Road: A Literature Survey. Ocul Immunol Inflamm. 2017;25(1):37-40. doi: 10.3109/09273948.2015.1136422.
69. Higashi K, Meguro A, Takeuchi M, Yamane T, Kitaichi N, Horie Y, Namba K, Ohno S, Nakao K, Sakamoto T, Sakai T, Tsuneoka H, Keino H, Okada AA, Takeda A, Fukuhara T, Mashimo H, Ohguro N, Oono S, Enaida H, Okinami S, Mizuki N. Investigation of Association between IL10 Gene Polymorphisms and Vogt-Koyanagi-Harada Disease in a Japanese Population. Ophthalmic Genet. 2017;38(2):187-189. doi: 10.3109/13816810.2016.1145698.
70. Matsuzawa A, Hayashi T, Oyakawa I, Yuda K, Shimizu T, Mizuki N, Yamada N, Kato N. Use of four asymmetric marks to orient the donor graft during Descemet's membrane endothelial keratoplasty. BMJ Open Ophthalmol. 2017;1(1):e000080. doi: 10.1136/bmjophth-2017-000080.
71. Ishihara M, Shibuya E, Tanaka S, Mizuki N. Diagnostic and therapeutic evaluation of multiple choroidal granulomas in a patient with confirmed sarcoidosis using enhanced depth imaging optical coherence tomography. Int Ophthalmol. 2018;38(6):2603-2608. doi: 10.1007/s10792-017-0720-2.
72. Ishido M, Horita N, Takeuchi M, Shibuya E, Yamane T, Kawagoe T, Ishido T, Minegishi K, Yoshimi R, Kirino Y, Hirohata S, Ishigatsubo Y, Takeno M, Kaneko T, Mizuki N. Distinct clinical features between acute and chronic progressive parenchymal neuro-Behçet disease: meta-analysis. Sci Rep. 2017;7(1):10196. doi: 10.1038/s41598-017-09938-z.
73. Shimizu T, Hayashi T, Yuda K, Tsuchiya A, Oyakawa I, Mizuki N, Kato N. Chandelier Illumination for Descemet Membrane Endothelial Keratoplasty. Cornea. 2017;36(9):1155-1157. doi: 10.1097/ICO.0000000000001254.
74. Nagashima T, Ishihara M, Shibuya E, Nakamura S, Mizuki N. Three cases of tubulointerstitial nephritis and uveitis syndrome with different clinical manifestations. Int Ophthalmol. 2017;37(3):753-759. doi: 10.1007/s10792-016-0321-5.
75. Okui S, Meguro A, Takeuchi M, Yamane T, Okada E, Iijima Y, Mizuki N. Analysis of the association between the LUM rs3759223 variant and high myopia in a Japanese population. Clin Ophthalmol. 2016;10:2157-2163.
76. Umemura T, Joshita S, Hamano H, Yoshizawa K, Kawa S, Tanaka E, Ota M. Association of autoimmune hepatitis with Src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients. J Hum Genet. 2017;62(11):963-967. doi: 10.1038/jhg.2017.74.
77. Carapito R, Gottenberg JE, Kotova I, Untrau M, Michel S, Naegely L, Aouadi I, Kwemou M, Paul N, Pichot A, Locke J, Bowman SJ, Griffiths B, Sivils KL, Sibilia J, Inoko H, Micelli-Richard C, Nocturne G, Ota M, Ng WF, Mariette X, Bahram S. A new MHC-linked susceptibility locus for primary Sjögren's syndrome: MICA. Hum Mol Genet. 2017;26(13):2565-2576. doi: 10.1093/hmg/ddx135.
78. Nagamatsu K, Sekijima Y, Nakamura K, Nakamura K, Hattori K, Ota M, Shimizu Y, Endo F, Ikeda SI. Prevalence of Fabry disease and GLA c.196G>C variant in Japanese stroke patients. J Hum Genet. 2017;62(7):665-670. doi: 10.1038/jhg.2017.31.
79. Joshita S, Umemura T, Tanaka E, Ota M. Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis. J Immunol Res. 2017;2017:3073504. doi: 10.1155/2017/3073504.
80. Cole AM, Cox S, Jeong C, Petousi N, Aryal DR, Droma Y, Hanaoka M, Ota M, Kobayashi N, Gasparini P, Montgomery H, Robbins P, Di Rienzo A, Cavalleri GL. Genetic structure in the Sherpa and neighboring Nepalese populations. BMC Genomics. 2017;18(1):102. doi: 10.1186/s12864-016-3469-5.
81. Umemura T, Sekiguchi T, Joshita S, Yamazaki T, Fujimori N, Shibata S, Ichikawa Y, Komatsu M, Matsumoto A, Shums Z, Norman GL, Tanaka E, Ota M. Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis. Liver Int. 2017;37(6):897-905. doi: 10.1111/liv.13316.
82. Ota M, Umemura T, Kawa S. Immunogenetics of IgG4-Related AIP. Curr Top Microbiol Immunol. 2017;401:35-44. doi: 10.1007/82_2016_37.
2016年
83. Horie Y, Kitaichi N, Hijioka K, Sonoda KH, Saishin Y, Kezuka T, Goto H, Takeuchi M, Nakamura S, Kimoto T, Shimakawa M, Kita M, Sugita S, Mochizuki M, Hori J, Iwata M, Shoji J, Fukuda M, Kaburaki T, Numaga J, Kawashima H, Fukushima A, Joko T, Takai N, Ozawa Y, Meguro A, Mizuki N, Namba K, Ishida S, Ohno S. Ocular Behçet's disease is less complicated with allergic disorders. A nationwide survey in Japan. Clin Exp Rheumatol. 2016;34(6 Suppl 102):111-114.
84. Yoshino A, Polouliakh N, Meguro A, Takeuchi M, Kawagoe T, Mizuki N. Chum salmon egg extracts induce upregulation of collagen type I and exert antioxidative effects on human dermal fibroblast cultures. Clin Interv Aging. 2016;11:1159-1168. doi: 10.2147/CIA.S102092.
85. Levinson RD, Yung M, Meguro A, Ashouri E, Yu F, Mizuki N, Ohno S, Rajalingam R. KIR and HLA Genotypes Implicated in Reduced Killer Lymphocytes Immunity Are Associated with Vogt-Koyanagi-Harada Disease. PLoS One. 2016;11(8):e0160392. doi: 10.1371/journal.pone.0160392.
86. Ogasawara M, Meguro A, Sakai T, Mizuki N, Takahashi T, Fujihara K, Tsuneoka H, Shikishima K. Genetic analysis of the aquaporin-4 gene for anti-AQP4 antibody-positive neuromyelitis optica in a Japanese population. Jpn J Ophthalmol. 2016;60(3):198-205. doi: 10.1007/s10384-016-0441-5.
87. Nakamura K, Miyano K, Tsuchida T, Meguro A, Mizuki N. Interleukin-17A gene polymorphism with the susceptibility of intestinal symptoms in patients with Behçet's disease. J Dermatol. 2016;43(6):708-709. doi: 10.1111/1346-8138.13251.
88. Nishisako M, Meguro A, Nomura E, Yamane T, Takeuchi M, Ota M, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Chin S, Ohno S, Inoko H, Mizuki N. SLC1A1 Gene Variants and Normal Tension Glaucoma: An Association Study. Ophthalmic Genet. 2016;37(2):194-200. doi: 10.3109/13816810.2015.1028649.
89. Oguchi T, Ota M, Ito T, Hamano H, Arakura N, Katsuyama Y, Meguro A, Kawa S. Correction: Investigation of Susceptibility Genes Triggering Lachrymal/Salivary Gland Lesion Complications in Japanese Patients with Type 1 Autoimmune Pancreatitis. PLoS One. 2016;11(1):e0146738. doi: 10.1371/journal.pone.0146738.
90. Hirayama A, Joshita S, Kitahara K, Mukawa K, Suga T, Umemura T, Tanaka E, Ota M. Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease. Dis Markers. 2016;2016:6485343.
91. Carapito R, Jung N, Kwemou M, Untrau M, Michel S, Pichot A, Giacometti G, Macquin C, Ilias W, Morlon A, Kotova I, Apostolova P, Schmitt-Graeff A, Cesbron A, Gagne K, Oudshoorn M, van der Holt B, Labalette M, Spierings E, Picard C, Loiseau P, Tamouza R, Toubert A, Parissiadis A, Dubois V, Lafarge X, Maumy-Bertrand M, Bertrand F, Vago L, Ciceri F, Paillard C, Querol S, Sierra J, Fleischhauer K, Nagler A, Labopin M, Inoko H, von dem Borne PA, Kuball JH, Ota M, Katsuyama Y, Michallet M, Lioure B, Peffault de Latour R, Blaise D, Cornelissen JJ, Yakoub-Agha I, Claas F, Moreau P, Milpied N, Charron D, Mohty M, Zeiser R, Socié G, Bahram S. Matching for the non-conventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD. Blood. 2016;128(15):1979-1986.
92. Umemura T, Joshita S, Yamazaki T, Komatsu M, Katsuyama Y, Yoshizawa K, Tanaka E, Ota M. Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan. Sci Rep. 2016;6:29770. doi: 10.1038/srep29770.
93. Yoshizawa K, Joshita S, Matsumoto A, Umemura T, Tanaka E, Morita S, Maejima T, Ota M. Incidence and prevalence of autoimmune hepatitis in the Ueda area, Japan. Hepatol Res. 2016 ;46(9):878-883. doi: 10.1111/hepr.12639.
2015年
94. Kanemaki N, Meguro A, Yamane T, Takeuchi M, Okada E, Iijima Y, Mizuki N. Study of association of PAX6 polymorphisms with susceptibility to high myopia in a Japanese population. Clin Ophthalmol. 2015;9:2005-2011. doi: 10.2147/OPTH.S95167.
95. Namba K, Goto H, Kaburaki T, Kitaichi N, Mizuki N, Asukata Y, Fujino Y, Meguro A, Sakamoto S, Shibuya E, Yokoi K, Ohno S. A Major Review: Current Aspects of Ocular Behçet's Disease in Japan. Ocul Immunol Inflamm. 2015;23(S1):S1-S23. doi: 10.3109/09273948.2014.981547.
96. Toyoda H, Miyagawa T, Koike A, Kanbayashi T, Imanishi A, Sagawa Y, Kotorii N, Kotorii T, Hashizume Y, Ogi K, Hiejima H, Kamei Y, Hida A, Miyamoto M, Imai M, Fujimura Y, Tamura Y, Ikegami A, Wada Y, Moriya S, Furuya H, Takeuchi M, Kirino Y, Meguro A, Remmers EF, Kawamura Y, Otowa T, Miyashita A, Kashiwase K, Khor SS, Yamasaki M, Kuwano R, Sasaki T, Ishigooka J, Kuroda K, Kume K, Chiba S, Yamada N, Okawa M, Hirata K, Mizuki N, Uchimura N, Shimizu T, Inoue Y, Honda Y, Mishima K, Honda M, Tokunaga K. A polymorphism in CCR1/CCR3 is associated with narcolepsy. Brain Behav Immun. 2015;49:148-155. doi: 10.1016/j.bbi.2015.05.003.
97. Miyake M, Yamashiro K, Tabara Y, Suda K, Morooka S, Nakanishi H, Khor CC, Chen P, Qiao F, Nakata I, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Meguro A, Kusuhara S, Polasek O, Hayward C, Wright AF, Campbell H, Richardson AJ, Schache M, Takeuchi M, Mackey DA, Hewitt AW, Cuellar G, Shi Y, Huang L, Yang Z, Leung KH, Kao PY, Yap MK, Yip SP, Moriyama M, Ohno-Matsui K, Mizuki N, MacGregor S, Vitart V, Aung T, Saw SM, Tai ES, Wong TY, Cheng CY, Baird PN, Yamada R, Matsuda F; Nagahama Study Group, Yoshimura N. Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia. Nat Commun. 2015;6:6689. doi: 10.1038/ncomms7689.
98. Bakir-Gungor B, Remmers EF, Meguro A, Mizuki N, Kastner DL, Gul A, Sezerman OU. Reply to Stoimenis et al. Eur J Hum Genet. 2015;23(10):1280. doi: 10.1038/ejhg.2014.288.
99. Bakir-Gungor B, Remmers EF, Meguro A, Mizuki N, Kastner DL, Gul A, Sezerman OU. Identification of possible pathogenic pathways in Behçet's disease using genome-wide association study data from two different populations. Eur J Hum Genet. 2015;23(5):678-687. doi: 10.1038/ejhg.2014.158.
100. Tanaka J, Tanaka H, Mizuki N, Nomura E, Ito N, Nomura N, Yamane M, Hida T, Goshima Y, Hatano H, Nakagawa H. Semaphorin 3A controls allergic and inflammatory responses in experimental allergic conjunctivitis. Int J Ophthalmol. 2015;8(1):1-10. doi: 10.3980/j.issn.2222-3959.2015.01.01.
101. Takase H, Okada AA, Goto H, Mizuki N, Namba K, Ohguro N, Sonoda KH, Tomita M, Keino H, Kezuka T, Kubono R, Mizuuchi K, Shibuya E, Takahashi H, Yanai R, Mochizuki M. Development and validation of new diagnostic criteria for acute retinal necrosis. Jpn J Ophthalmol. 2015;59(1):14-20. doi: 10.1007/s10384-014-0362-0.
102. Lennikov A, Alekberova Z, Goloeva R, Kitaichi N, Denisov L, Namba K, Takeno M, Ishigatsubo Y, Mizuki N, Nasonov E, Ishida S, Ohno S. Single center study on ethnic and clinical features of Behcet's disease in Moscow, Russia. Clin Rheumatol. 2015;34(2):321-327. doi: 10.1007/s10067-013-2442-9.
103. Carapito R, Shahram F, Michel S, Le Gentil M, Radosavljevic M, Meguro A, Abdollahi BS, Inoko H, Ota M, Davatchi F, Bahram S. On the genetics of the Silk Route: association analysis of HLA, IL10, and IL23R-IL12RB2 regions with Behçet's disease in an Iranian population. Immunogenetics. 2015;67(5-6):289-293. doi: 10.1007/s00251-015-0841-6.
104. Umemura T, Joshita S, Sekiguchi T, Usami Y, Shibata S, Kimura T, Komatsu M, Matsumoto A, Ota M, Tanaka E. Serum Wisteria Floribunda agglutinin-positive Mac-2-binding protein level predicts liver fibrosis and prognosis in primary biliary cirrhosis. Am J Gastorenterol. 2015;110(6):857-864. doi: 10.1038/ajg.2015.118.
105. Ozaki Y, Suzuki S, Kashiwase K, Shigenari A, Okudaira Y, Ito S, Masuya A, Azuma F, Yabe T, Morishima S, Mitsunaga S, Satake M, Ota M, Morishima Y, Kulski JK, Saito K, Inoko H, Shiina T. Cost-efficient multiplex PCR for routine genotyping of up to nine classical HLA loci in a single analytical run of multiple samples by next generation sequencing. BMC Genomics. 2015;16:318. doi: 10.1186/s12864-015-1514-4.
106. Umemura T, Ota M. Genetic factors affect the etiology, clinical characteristics and outcome of autoimmune hepatitis. Clin J Gastroenterol. 2015;8(6):360-366. doi: 10.1007/s12328-015-0620-9.
107. Nunotani M, Shiozaki T, Sato N, Kamei S, Takatsu K, Hayashi T, Ota M, Asamura H. Analysis of 30 insertion-deletion polymorphisms in the Japanese population using the Investigator DIPplex® kit. Leg Med (Tokyo). 2015;17(6):467-470. doi: 10.1016/j.legalmed.2015.10.002.
108. Sekiguchi T, Umemura T, Fujimori N, Shibata S, Ichikawa Y, Kimura T, Joshita S, Komatsu M, Matsumoto A, Tanaka E, Ota M. Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosis. PLoS One. 2015;10(6):e0131658. doi: 10.1371/journal.pone.0131658.
2014年
109. Nakasato H, Uemoto R, Isozaki M, Meguro A, Kawagoe T, Mizuki N. Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol. 2014;252(6):977-982. doi: 10.1007/s00417-014-2616-4.
110. Suzuki T, Meguro A, Matsushima M, Masui A, Tsuda S, Nakamura J, Nishina R, Uchida T, Yuhara H, Igarashi M, Koike J, Mine T, Inoko H, Takagi A. Investigation of the Association of TLR2 and TLR4 Polymorphisms with Susceptibility to Helicobacter pylori-Related Gastrointestinal Diseases. Open J Intern Med. 2014;4:130-136. doi: 10.4236/ojim.2014.44020.
111. Nakasato H, Uemoto R, Meguro A, Kawagoe T, Hatano H, Mizuki N. Treatment of symptomatic inferior conjunctivochalasis by ligation. Acta Ophthalmol. 2014;92(5):e411-412. doi: 10.1111/aos.12349.
112. Takeuchi M, Kezuka T, Sugita S, Keino H, Namba K, Kaburaki T, Maruyama K, Nakai K, Hijioka K, Shibuya E, Komae K, Hori J, Ohguro N, Sonoda KH, Mizuki N, Okada AA, Ishibashi T, Goto H, Mochizuki M. Evaluation of the long-term efficacy and safety of infliximab treatment for uveitis in Behçet's disease: a multicenter study. Ophthalmology. 2014;121(10):1877-1884. doi: 10.1016/j.ophtha.2014.04.042.
113. Nishide T, Hayakawa N, Shibuya E, Yagi Y, Mizuki N. Choroidal thickness is affected by many factors which may change the effect of ranibizumab: author's response. Graefes Arch Clin Exp Ophthalmol. 2014;252(5):849-850. doi: 10.1007/s00417-014-2597-3.
114. Kaburaki T, Namba K, Sonoda KH, Kezuka T, Keino H, Fukuhara T, Kamoi K, Nakai K, Mizuki N, Ohguro N; Ocular Behçet Disease Research Group of Japan. Behçet's disease ocular attack score 24: evaluation of ocular disease activity before and after initiation of infliximab. Jpn J Ophthalmol. 2014;58(2):120-130. doi: 10.1007/s10384-013-0294-0.
115. Nishide T, Hayakawa N, Kimura I, Nakanishi M, Yagi Y, Shibuya E, Mizuki N. Postoperative refractive error following cataract surgery after the first attack of acute primary angle closure. Int Ophthalmol. 2014;34(4):805-808.
116. Joshita S, Umemura T, Ota M, Tanaka E. AST/platelet ratio index associates with progression to hepatic failure and correlates with histological fibrosis stage in Japanese patients with primary biliary cirrhosis. J Hepatol. 2014;61(6):1443-1445. doi: 10.1016/j.jhep.2014.07.036.
117. Umemura T, Katsuyama Y, Yoshizawa K, Kimura T, Joshita S, Komatsu M, Matsumoto A, Tanaka E, Ota M. Human leukocyte antigen class II haplotypes affects clinical characteristics and progression of type 1 autoimmune hepatitis in Japan. PLoS One. 2014;9(6):e100565. doi: 10.1371/journal.pone.0100565.
118. Umemura T, Ota M, Katsuyama Y, Wada S, Mori H, Maruyama A, Shibata S, Nozawa Y, Kimura T, Morita S, Joshita S, Komatsu M, Matsumoto A, Kamijo A, Kobayashi M, Takamatsu M, Yoshizawa K, Kiyosawa K, Tanaka E. KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C. Hum Immunol. 2014;75(8):822-826. doi: 10.1016/j.humimm.2014.06.003.
119. Nozawa Y, Umemura T, Katsuyama Y, Shibata S, Kimura T, Morita S, Joshita S, Komatsu M, Matsumoto A, Yoshizawa K, Ota M, Tanaka E. Genetic polymorphism in IFNL4 and response to pegylated interferon-α and ribavirin in Japanese chronic hepatitis C patients. Tissue Antigens. 2014;83(1):45-48. doi: 10.1111/tan.12264.
120. Joshita S, Umemura T, Nakamura M, Katsuyama Y, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Ishibashi H, Tanaka E, Ota M. STAT4 gene polymorphisms are associated with susceptibility and ANA status in primary biliary cirrhosis. Dis Markers. 2014;2014:727393. doi: 10.1155/2014/727393.
121. Ozaki Y, Suzuki S, Shigenari A, Okudaira Y, Kikkawa E, Oka A, Ota M, Mitsunaga S, Kulski JK, Inoko H, Shiina T. HLA-DRB1, -DRB3, -DRB4 and -DRB5 genotyping at a super-high resolution level by long range PCR and high-throughput sequencing. Tissue Antigens. 2014;83(1):10-16. doi: 10.1111/tan.12258.
122. Harayama Y, Kamei S, Sato N, Hayashi T, Shiozaki T, Ota M, Asamura H. Analysis of Y chromosome haplogroups in Japanese population using short amplicons and its application in forensic analysis. Leg Med (Tokyo). 2014;16(1):20-25. doi: 10.1016/j.legalmed.2013.10.005.
123. Okuhara S, Umemura T, Joshita S, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Katsuyama Y, Ota M, Tanaka E. Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B. Hepatol Res. 2014;44(10):E172-180. doi: 10.1111/hepr.12287.
2013年
124. Yoshida M, Meguro A, Okada E, Nomura N, Mizuki N. Association study of fibroblast growth factor 10 (FGF10) polymorphisms with susceptibility to extreme myopia in a Japanese population. Mol Vis. 2013;19:2321-2329.
125. Yoshida M, Meguro A, Yoshino A, Nomura N, Okada E, Mizuki N. Association study of IGF1 polymorphisms with susceptibility to high myopia in a Japanese population. Clin Ophthalmol. 2013;7:2057-2062. doi: 10.2147/OPTH.S52726.
126. Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; Fuchs' Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet. 2013;93(2):264-277. doi: 10.1016/j.ajhg.2013.06.016.
127. Kanemaki N, Tchedre KT, Imayasu M, Kawarai S, Sakaguchi M, Yoshino A, Itoh N, Meguro A, Mizuki N. Dogs and Humans Share a Common Susceptibility Gene SRBD1 for Glaucoma Risk. PLoS One. 2013;8(9):e74372. doi: 10.1371/journal.pone.0074372.
128. Kato T, Meguro A, Nomura E, Uemoto R, Nomura N, Ota M, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Chin S, Ohno S, Inoko H, Mizuki N. Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population. Eye (Lond). 2013;27(8):979-983. doi: 10.1038/eye.2013.123.
129. Kirino Y, Zhou Q, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Ugurlu S, Erer B, Abaci N, Ustek D, Meguro A, Ueda A, Takeno M, Inoko H, Ombrello MJ, Satorius CL, Maskeri B, Mullikin JC, Sun HW, Gutierrez-Cruz G, Kim Y, Wilson AF, Kastner DL, Gül A, Remmers EF. Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behcet disease. Proc Natl Acad Sci U S A. 2013;110(20):8134-8139. doi: 10.1073/pnas.1306352110.
130. Yotsumoto S, Meguro A, Ishihara M, Uemoto R, Ota M, Morimoto SI, Kaburaki T, Ando Y, Takenaka S, Ohno S, Inoko H, Mizuki N. Investigation of the Association Between Toll-like Receptor 9 Gene Polymorphisms and Sarcoidosis in Japanese Patients. Ocul Immunol Inflamm. 2013;21(3):234-236. doi: 10.3109/09273948.2012.756114.
131. Mikami T, Meguro A, Teshigawara T, Takeuchi M, Uemoto R, Kawagoe T, Nomura E, Asukata Y, Ishioka M, Iwasaki M, Fukagawa K, Konomi K, Shimazaki J, Nishida T, Mizuki N. Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population. Mol Vis. 2013;19:845-851.
132. Kirino Y, Bertsias G, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Sacli FS, Erer B, Inoko H, Emrence Z, Cakar A, Abaci N, Ustek D, Satorius C, Ueda A, Takeno M, Kim Y, Wood GM, Ombrello MJ, Meguro A, Gül A, Remmers EF, Kastner DL. Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. Nat Genet. 2013;45(2):202-207. doi: 10.1038/ng.2520.
133. Nakasato-Sonn H, Uemoto R, Meguro A, Mizuki N. Modification of Swan-Jacobs lens for iridocorneal angle surgery. Graefes Arch Clin Exp Ophthalmol. 2013;251(9):2247-2248. doi: 10.1007/s00417-012-2232-0.
134. Uemoto R, Nakasato-Sonn H, Meguro A, Ito N, Yazama F, Mizuki N. Staining internal limiting membrane with a mixture of BBG and sodium hyaluronate. Br J Ophthalmol. 2013;97(6):690-693. doi: 10.1136/bjophthalmol-2012-302289.
135. Lee YJ, Horie Y, Wallace GR, Choi YS, Park JA, Song R, Kang YM, Kang SW, Baek HJ, Kitaichi N, Meguro A, Mizuki N, Namba K, Ishida S, Kim J, Niemczek E, Lee EY, Song YW, Ohno S, Lee EB. Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease. Ann Rheum Dis. 2013;72(9):1510-1516. doi: 10.1136/annrheumdis-2011-200288.
136. Nishide T, Nakanishi M, Hayakawa N, Kimura I, Mizuki N. Cataract surgery for tilted lens in peters' anomaly type 2. Case Rep Ophthalmol. 2013;4(3):134-137. doi: 10.1159/000354611.
137. Miwa M, Iwanami M, Oba MS, Mizuki N, Nishida T. Comparison of LogMAR Eye charts with angular vision for visually impaired: the Berkeley rudimentary vision test vs LogMAR One target Landolt ring Eye chart. Graefes Arch Clin Exp Ophthalmol. 2013;251(12):2761-2767. doi: 10.1007/s00417-013-2469-2.
138. Nishide T, Hayakawa N, Nakanishi M, Ishii M, Okazaki S, Kimura I, Shibuya E, Mizuki N. Reduction in choroidal thickness of macular area in polypoidal choroidal vasculopathy patients after intravitreal ranibizumab therapy. Graefes Arch Clin Exp Ophthalmol. 2013;251(10):2415-2420. doi: 10.1007/s00417-013-2419-z.
139. Nishide T, Hayakawa N, Nakanishi M, Ishii M, Kimura I, Shibuya E, Nomura E, Mizuki N. Preoperative factors associated with improvement in visual acuity after globe rupture treatment. Eur J Ophthalmol. 2013;23(5):718-722. doi: 10.5301/ejo.5000252.
140. Ando K, Ishihara M, Kusumoto Y, Shibuya E, Nakamura S, Mizuki N. A case of corneal endotheliitis with mumps virus RNA in aqueous humor detected by rt-PCR. Ocul Immunol Inflamm. 2013;21(2):150-152. doi: 10.3109/09273948.2012.747619.
141. Nakasato H, Uemoto R, Kawagoe T, Okada E, Mizuki N. Authors' response: immediate removal of posteriorly dislocated lens fragments through sclerocorneal incision during cataract surgery. Br J Ophthalmol. 2013;97(2):234-235. doi: 10.1136/bjophthalmol-2012-302704.
142. Iwahashi-Shima C, Azumi A, Ohguro N, Okada AA, Kaburaki T, Goto H, Sonoda KH, Namba K, Mizuki N, Mochizuki M. Acute retinal necrosis: factors associated with anatomic and visual outcomes. Jpn J Ophthalmol. 2013;57(1):98-103. doi: 10.1007/s10384-012-0211-y.
143. Nozawa Y, Umemura T, Joshita S, Katsuyama Y, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Tanaka E, Ota M. KIR, HLA, and IL28B variant predict response to antiviral therapy in genotype 1 chronic hepatitis C patients in Japan. PLoS One. 2013;8(12):e83381. doi: 10.1371/journal.pone.0083381.
144. Kobayashi N, Hanaoka M, Droma Y, Ito M, Katsuyama Y, Kubo K, Ota M. Polymorphisms of the tissue inhibitor of metalloproteinase 3 gene are associated with resistance to high-altitude pulmonary edema (HAPE) in a Japanese population: a case control study using polymorphic microsatellite markers. PLoS One. 2013;8(8):e71993. doi: 10.1371/journal.pone.0071993.
145. Kita Y, Hosomichi K, Suzuki S, Inoko H, Shiina T, Watanabe M, Tanaka A, Horie T, Ohizumi H, Tanaka S, Iwasaki T, Ota M, Kulski JK. Genetic and family structure in a group of 165 common bottlenose dolphins caught off the Japanese coast. Mar Mamm Sci. 2013;29(3):474-496. doi: 10.1111/j.1748-7692.2012.00581.x.
146. Joshita S, Shirahata K, Yazaki Y, Okaniwa S, Nakamura Y, Kimura T, Noami S, Horigome R, Yagi H, Ito N, Yamazaki A, Akahane Y, Umemura T, Yoshizawa K, Tanaka E, Ota M. Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy. Hepatol Res. 2013;43(7):801-807. doi: 10.1111/hepr.12021.
147. Watanabe T, Maruyama M, Ito T, Kanai K, Oguchi T, Muraki T, Hamano H, Arakura N, Ota M, Kawa S. c Intern Med. 2013;52(8):895-899.
148. Morita S, Joshita S, Umemura T, Katsuyama Y, Kimura T, Komatsu M, Matsumoto A, Yoshizawa K, Kamijo A, Yamamura N, Tanaka E, Ota M. Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis. Hum Immunol. 2013;74(2):219-222. doi: 10.1016/j.humimm.2012.10.022.
2012年以前
149. Suzuki H, Ota M, Meguro A, Katsuyama Y, Kawagoe T, Ishihara M, Asukata Y, Takeuchi M, Ito N, Shibuya E, Nomura E, Uemoto R, Nishide T, Namba K, Kitaichi N, Morimoto S, Kaburaki T, Ando Y, Takenaka S, Nakamura J, Saeki K, Ohno S, Inoko H, Mizuki N. Genetic Characterization and Susceptibility for Sarcoidosis in Japanese Patients: Risk Factors of BTNL2 Gene Polymorphisms and HLA Class II Alleles. Invest Ophthalmol Vis Sci. 2012;53(11):7109-7115. doi: 10.1167/iovs.12-10491.
150. Meguro A, Ideta H, Ota M, Ito N, Ideta R, Yonemoto J, Takeuchi M, Uemoto R, Nishide T, Iijima Y, Kawagoe T, Okada E, Shiota T, Hagihara Y, Oka A, Inoko H, Mizuki N. Common variants in the COL4A4 gene confer susceptibility to lattice degeneration of the retina. PLoS One. 2012;7(6):e39300. doi: 10.1371/journal.pone.0039300.
151. Fan Q, Barathi VA, Cheng CY, Zhou X, Meguro A, Nakata I, Khor CC, Goh LK, Li YJ, Lim W, Ho CE, Hawthorne F, Zheng Y, Chua D, Inoko H, Yamashiro K, Ohno-Matsui K, Matsuo K, Matsuda F, Vithana E, Seielstad M, Mizuki N, Beuerman RW, Tai ES, Yoshimura N, Aung T, Young TL, Wong TY, Teo YY, Saw SM. Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. PLoS Genet. 2012;8(6):e1002753. doi: 10.1371/journal.pgen.1002753.
152. Sakuyama K, Meguro A, Ota M, Ishihara M, Uemoto R, Ito H, Okada E, Namba K, Kitaichi N, Morimoto S, Kaburaki T, Ando Y, Takenaka S, Yuasa T, Ohno S, Inoko H, Mizuki N. Lack of association between IL10 polymorphisms and sarcoidosis in Japanese patients. Mol Vis. 2012;18:512-518.
153. Kawase K, Allingham RR, Meguro A, Mizuki N, Roos B, Solivan-Timpe FM, Robin AL, Ritch R, Fingert JH. Confirmation of TBK1 duplication in normal tension glaucoma. Exp Eye Res. 2012;96(1):178-180. doi: 10.1016/j.exer.2011.12.021.
154. Uemoto R, Nakasato-Sonn H, Kawagoe T, Meguro A, Okada E, Mizuki N. Factors associated with enlargement of chorioretinal atrophy after intravitreal bevacizumab for myopic choroidal neovascularization. Graefes Arch Clin Exp Ophthalmol. 2012;250(7):989-997. doi: 10.1007/s00417-011-1921-4.
155. Horie Y, Meguro A, Kitaichi N, Lee EB, Kanda A, Noda K, Song YW, Park KS, Namba K, Ota M, Inoko H, Mizuki N, Ishida S, Ohno S. Replication of a microsatellite genome-wide association study of Behcet's disease in a Korean population. Rheumatology (Oxford). 2012;51(6):983-986. doi: 10.1093/rheumatology/ker444.
156. Uemoto R, Nakasato-Sonn H, Meguro A, Okada E, Mizuki N. Anatomical and functional changes of retina following subretinal injection of high-speed fluid. Graefes Arch Clin Exp Ophthalmol. 2012;250(3):447-450. doi: 10.1007/s00417-011-1800-z.
157. Omoto S, Kuroiwa Y, Otsuka S, Wang C, Mizuki N, Nagatani H, Hirayama Y. Modulation of human visual evoked potentials in 3-dimensional perception after stimuli produced with an integral imaging method. Clin EEG Neurosci. 2012;43(4):303-311. doi: 10.1177/1550059412445608.
158. Nakasato H, Uemoto R, Mizuki N. Treatment of pterygium by ligation and bevacizumab injection. Cornea. 2012;31(11):1339-41. doi: 10.1097/ICO.0b013e3182408bc7.
159. Nakasato H, Uemoto R, Kawagoe T, Okada E, Mizuki N. Immediate removal of posteriorly dislocated lens fragments through sclerocorneal incision during cataract surgery. Br J Ophthalmol. 2012;96(8):1058-1062. doi: 10.1136/bjophthalmol-2011-300864.
160. Takeuchi M, Asukata Y, Kawagoe T, Ito N, Nishide T, Mizuki N. Infliximab monotherapy versus infliximab and colchicine combination therapy in patients with Behçet's disease. Ocul Immunol Inflamm. 2012;20(3):193-197. doi: 10.3109/09273948.2012.665124.
161. Kurihara Y, Arie Y, Iketani M, Ito H, Nishiyama K, Sato Y, Nakamura F, Mizuki N, Goshima Y, Takei K. The carboxyl-terminal region of Crtac1B/LOTUS acts as a functional domain in endogenous antagonism to Nogo receptor-1. Biochem Biophys Res Commun. 2012;418(2):390-395. doi: 10.1016/j.bbrc.2012.01.033.
162. Nakasato S, Uemoto R, Mizuki N. Thermocautery for inferior conjunctivochalasis. Cornea. 2012;31(5):514-519. doi: 10.1097/ICO.0b013e3181dc81d2.
163. Suzuki M, Suzuki T, Nagano A, Hirasawa M, Sakuyama K, Mizuki N. Cyclooxygenase inhibitor improved an exudative lesion of choroidal neovascularization in age-related macular degeneration. Eur J Ophthalmol. 2012;22(3):495-498. doi: 10.5301/ejo.5000032.
164. Ito R, Ota M, Meguro A, Katsuyama Y, Uemoto R, Nomura E, Nishide T, Kitaichi N, Horie Y, Namba K, Ohno S, Inoko H, Mizuki N. Investigation of association between TLR9 gene polymorphisms and VKH in Japanese patients. Ocul Immunol Inflamm. 2011;19(3):202-205. doi: 10.3109/09273948.2011.553981.
165. Yasumura R, Meguro A, Ota M, Nomura E, Uemoto R, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucoma. Mol Vis. 2011;17:792-796.
166. Sato M, Kawagoe T, Meguro A, Ota M, Katsuyama Y, Ishihara M, Namba K, Kitaichi N, Morimoto S, Kaburaki T, Ando Y, Takenaka S, Ohno S, Inoko H, Mizuki N. Toll-like receptor 2 (TLR2) gene polymorphisms are not associated with sarcoidosis in the Japanese. Mol Vis. 2011;17:731-736.
167. Sada T, Ota M, Katsuyama Y, Meguro A, Nomura E, Uemoto R, Nishide T, Okada E, Ohno S, Inoko H, Mizuki N. Association analysis of Toll-like receptor 7 gene polymorphisms and Behçet's disease in Japanese. Hum Immunol. 2011;72(3):269-272. doi: 10.1016/j.humimm.2010.12.007.
168. Takase H, Okada AA, Goto H, Mizuki N, Namba K, Ohguro N, Sonoda KH, Tomita M, Keino H, Kezuka T, Kubono R, Mizuuchi K, Shibuya E, Takahashi H, Yanai R, Mochizuki M. Development and validation of new diagnostic criteria for acute retinal necrosis. Jpn J Ophthalmol. 2015;59(1):14-20. doi: 10.1007/s10384-014-0362-0.
169. Kawagoe T, Mizuki N. Sarcoidosis. Curr Opin Ophthalmol. 2011;22(6):502-7. doi: 10.1097/ICU.0b013e32834bbd7e.
170. Nishida T, Shibuya E, Asukata Y, Nakamura S, Ishihara M, Hayashi K, Takeno M, Ishigatsubo Y, Mizuki N. Clinical Course before and after Cataract and Glaucoma Surgery under Systemic Infliximab Therapy in Patients with Behçet's Disease. Case Rep Ophthalmol. 2011;2(2):189-192. doi: 10.1159/000329190.
171. Yanagimachi M, Miyamae T, Naruto T, Hara T, Kikuchi M, Hara R, Imagawa T, Mori M, Kaneko T, Goto H, Morita S, Mizuki N, Kimura A, Yokota S. Association of HLA-A*02:06 and HLA-DRB1*04:05 with clinical subtypes of juvenile idiopathic arthritis. J Hum Genet. 2011;56(3):196-199. doi: 10.1038/jhg.2010.159.
172. Meguro A, Inoko H, Ota M, Katsuyama Y, Oka A, Okada E, Yamakawa R, Yuasa T, Fujioka T, Ohno S, Bahram S, Mizuki N. Genetics of Behcet disease inside and outside the MHC. Ann Rheum Dis. 2010;69(4):747-754. doi: 10.1136/ard.2009.108571.
173. Suzuki M, Meguro A, Ota M, Nomura E, Kato T, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma. Mol Vis. 2010;16:1874-1879.
174. Kurata R, Nakaoka H, Tajima A, Hosomichi K, Shiina T, Meguro A, Mizuki N, Ohono S, Inoue I, Inoko H. TRIM39 and RNF39 are associated with Behcet's disease independently of HLA-B*51 and -A*26. Biochem Biophys Res Commun. 2010;401(4):533-537. doi: 10.1016/j.bbrc.2010.09.088.
175. Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H. Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci. Nat Genet. 2010;42(8):703-706. doi: 10.1038/ng.624.
176. Writing Committee for the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N, Bahram S. Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. Ophthalmology. 2010;117(7):1331-1338. doi: 10.1016/j.ophtha.2009.12.001.
177. Murakami K, Meguro A, Ota M, Shiota T, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma. Mol Vis. 2010;16:462-466.
178. Suzuki M, Noda K, Kubota S, Hirasawa M, Ozawa Y, Tsubota K, Mizuki N, Ishida S. Eicosapentaenoic acid suppresses ocular inflammation in endotoxin-induced uveitis. Mol Vis. 2010;16:1382-1388.
179. Yamaguchi Y, Takahashi H, Satoh T, Okazaki Y, Mizuki N, Takahashi K, Ikezawa Z, Kuwana M. Natural killer cells control a T-helper 1 response in patients with Behçet's disease. Arthritis Res Ther. 2010;12(3):R80. doi: 10.1186/ar3005.
180. Omoto S, Kuroiwa Y, Otsuka S, Baba Y, Wang C, Li M, Mizuki N, Ueda N, Koyano S, Suzuki Y. P1 and P2 components of human visual evoked potentials are modulated by depth perception of 3-dimensional images. Clin Neurophysiol. 2010;121(3):386-391. doi: 10.1016/j.clinph.2009.12.005.
181. Nakamura J, Meguro A, Ota M, Nomura E, Nishide T, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma. Mol Vis. 2009;15:2905-2910.
182. Asukata Y, Ota M, Meguro A, Katsuyama Y, Ishihara M, Namba K, Kitaichi N, Morimoto S, Kaburaki T, Ando Y, Takenaka S, Inoko H, Ohno S, Mizuki N. Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan. Mol Vis. 2009;15:2673-2682.
183. Nakamura K, Ota M, Meguro A, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Association of microsatellite polymorphisms of the GPDS1 locus with normal tension glaucoma in the Japanese population. Clin Ophthalmol. 2009;3:307-312.
184. Kamio M, Meguro A, Ota M, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis. Clin Ophthalmol. 2009;3:183-188.
185. Horie Y, Meguro A, Ota M, Kitaichi N, Katsuyama Y, Takemoto Y, Namba K, Yoshida K, Song YW, Park KS, Lee EB, Inoko H, Mizuki N, Ohno S. Association of TLR4 polymorphisms with Behcet's disease in a Korean population. Rheumatology (Oxford). 2009;48(6):638-642. doi: 10.1093/rheumatology/kep077.
186. Tomiyama R, Meguro A, Ota M, Katsuyama Y, Nishide T, Uemoto R, Iijima Y, Ohno S, Inoko H, Mizuki N. Investigation of the association between Toll-like receptor 2 gene polymorphisms and Behcet's disease in Japanese patients. Hum Immunol. 2009;70(1):41-44. doi: 10.1016/j.humimm.2008.10.014.
187. Nishizaki R, Ota M, Inoko H, Meguro A, Shiota T, Okada E, Mok J, Oka A, Ohno S, Mizuki N. New susceptibility locus for high myopia is linked to the uromodulin-like 1 (UMODL1) gene region on chromosome 21q22.3. Eye (Lond). 2009;23(1):222-229. doi: 10.1038/eye.2008.152.
188. Uemoto R, Mizuki N. Ocular rupture after accidental intraocular injection of bupivacaine. Retin Cases Brief Rep. 2009;3(4):340-342. doi: 10.1097/ICB.0b013e31817f2e2e.
189. Albuquerque RJ, Hayashi T, Cho WG, Kleinman ME, Dridi S, Takeda A, Baffi JZ, Yamada K, Kaneko H, Green MG, Chappell J, Wilting J, Weich HA, Yamagami S, Amano S, Mizuki N, Alexander JS, Peterson ML, Brekken RA, Hirashima M, Capoor S, Usui T, Ambati BK, Ambati J. Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Nat Med. 2009;15(9):1023-1030. doi: 10.1038/nm.2018.
190. Uemoto R, Nakasato S, Mizuki N. New technique for inserting 27-gauge twinlight chandelier illumination fibers into the eye using intravenous cannula. Retina. 2009;29(7):1040-102. doi: 10.1097/IAE.0b013e3181a3b946.
191. Horie Y, Kitaichi N, Katsuyama Y, Yoshida K, Miura T, Ota M, Asukata Y, Inoko H, Mizuki N, Ishida S, Ohno S. Evaluation of PTPN22 polymorphisms and Vogt-Koyanagi-Harada disease in Japanese patients. Mol Vis. 2009;15:1115-1119.
192. Hayashi T, Yamagami S, Tanaka K, Yokoo S, Usui T, Amano S, Mizuki N. Immunologic mechanisms of corneal allografts reconstituted from cultured allogeneic endothelial cells in an immune-privileged site. Invest Ophthalmol Vis Sci. 2009;50(7):3151-3158. doi: 10.1167/iovs.08-2530.
193. Meguro A, Ota M, Katsuyama Y, Oka A, Ohno S, Inoko H, Mizuki N. Association of the toll-like receptor 4 gene polymorphisms with Behcet's disease. Ann Rheum Dis. 2008;67(5):725-727. doi: 10.1136/ard.2007.079871.
194. Shibuya E, Meguro A, Ota M, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Association of toll-like receptor 4 gene polymorphisms with normal tension glaucoma. Invest Ophthalmol Vis Sci. 2008;49(10):4453-4457. doi: 10.1167/iovs.07-1575.
195. Kamiishi T, Itoh Y, Meguro A, Nishida T, Sasaki S, Nanba K, Ohno S, Inoko H, Mizuki N. Four-digit allele genotyping of HLA-A and HLA-B genes in Japanese patients with Behçet's disease. Nippon Ganka Gakkai Zasshi. 2008;112(5):451-458.
196. Nomura N, Nomura M, Mizuki N, Hamada J. Rac1 mediates phorbol 12-myristate 13-acetate-induced migration of glioblastoma cells via paxillin. Oncol Rep. 2008;20(4):705-711.
197. Hayashi T, Yamagami S, Tanaka K, Yokoo S, Usui T, Amano S, Mizuki N. A mouse model of allogeneic corneal endothelial cell transplantation. Cornea. 2008;27(6):699-705. doi: 10.1097/QAI.0b013e31815e722b.
198. Asukata Y, Ishihara M, Hasumi Y, Nakamura S, Hayashi K, Ohno S, Mizuki N. Guidelines for the diagnosis of ocular sarcoidosis. Ocul Immunol Inflamm. 2008;16(3):77-81. doi: 10.1080/09273940802051100.
199. Hayashi T, Ishioka M, Ito N, Kato Y, Nakagawa H, Hatano H, Mizuki N. Bilateral herpes simplex keratitis in a patient with chronic graft-versus-host disease. Clin Ophthalmol. 2008;2(2):457-459.
200. Kirino Y, Takeno M, Watanabe R, Murakami S, Kobayashi M, Ideguchi H, Ihata A, Ohno S, Ueda A, Mizuki N, Ishigatsubo Y. Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behçet's disease. Arthritis Res Ther. 2008;10(1):R16. doi: 10.1186/ar2367.
201. Mizuki N, Meguro A, Tohnai I, Gül A, Ohno S, Mizuki N. Association of major histocompatibility complex class I chain-related gene A and HLA-B alleles with Behçet's disease in Turkey. Jpn J Ophthalmol. 2007;51(6):431-436.
202. Yamane T, Mok J, Oka A, Okada E, Nishizaki R, Meguro A, Yonemoto J, Kulski JK, Ohno S, Inoko H, Mizuki N. Lack of association with high myopia and the MYP2 locus in the Japanese population by high resolution microsatellite analysis on chromosome 18. Clin Ophthalmol. 2007;1(3):311-316.
203. Sasaki S, Ota M, Meguro A, Nishizaki R, Okada E, Mok J, Kimura T, Oka A, Katsuyama Y, Ohno S, Inoko H, Mizuki N. A single nucleotide polymorphism analysis of the LAMA1 gene in Japanese patients with high myopia. Clin Ophthalmol. 2007;1(3):289-295.
204. Horie Y, Kitaichi N, Takemoto Y, Namba K, Yoshida K, Hirose S, Hasumi Y, Ota M, Inoko H, Mizuki N, Ohno S. Polymorphism of IFN-gamma gene and Vogt-Koyanagi-Harada disease. Mol Vis. 2007;13:2334-2338.
205. Omoto S, Kuroiwa Y, Wang C, Li M, Mizuki N, Hakii Y. The effect of attended color on the P1/N1 component of visual event-related potentials. Neurosci Lett. 2007;429(1):22-27.
206. Teshigawara T, Hata S, Hayashi T, Watanabe Y, Itoh Y, Hitoi K, Mizuki N. Penetration of gatifloxacin eye drops into the aqueous humor in humans. Ocul Immunol Inflamm. 2007;15(4):309-313.
207. Katsuyama Y, Ota M, Mizuki N, Ito A, Okada E, Ohno S, Matsunaga T, Fukushima H, Ohmori S. MDR1 polymorphisms effect cyclosporine AUC0-4 values in Behçet's disease patients. Clin Ophthalmol. 2007 Sep;1(3):297-303.
208. Inamori Y, Ota M, Inoko H, Okada E, Nishizaki R, Shiota T, Mok J, Oka A, Ohno S, Mizuki N. The COL1A1 gene and high myopia susceptibility in Japanese. Hum Genet. 2007;122(2):151-157.
209. Hayashi T, Inoko H, Nishizaki R, Ohno S, Mizuki N. Exclusion of transforming growth factor-beta1 as a candidate gene for myopia in the Japanese. Jpn J Ophthalmol. 2007;51(2):96-99.
210. Matsuda A, Ebihara N, Kumagai N, Fukuda K, Ebe K, Hirano K, Sotozono C, Tei M, Hasegawa K, Shimizu M, Tamari M, Namba K, Ohno S, Mizuki N, Ikezawa Z, Shirakawa T, Hamuro J, Kinoshita S. Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts. Invest Ophthalmol Vis Sci. 2007;48(2):583-589.
211. Yatsu K, Mizuki N, Hirawa N, Oka A, Itoh N, Yamane T, Ogawa M, Shiwa T, Tabara Y, Ohno S, Soma M, Hata A, Nakao K, Ueshima H, Ogihara T, Tomoike H, Miki T, Kimura A, Mano S, Kulski JK, Umemura S, Inoko H. High-resolution mapping for essential hypertension using microsatellite markers. Hypertension. 2007;49(3):446-452.
212. Itoh Y, Inoko H, Kulski JK, Sasaki S, Meguro A, Takiyama N, Nishida T, Yuasa T, Ohno S, Mizuki N. Four-digit allele genotyping of the HLA-A and HLA-B genes in Japanese patients with Behcet’s disease by a PCR-SSOP-Luminex method. Tissue Antigens. 2006;67(5):390-394.
213. Horie Y, Takemoto Y, Miyazaki A, Namba K, Kase S, Yoshida K, Ota M, Hasumi Y, Inoko H, Mizuki N, Ohno S. Tyrosinase gene family and Vogt-Koyanagi-Harada disease in Japanese patients. Mol Vis. 2006;12:1601-1605.
214. Matsui K, Saha S, Saitoh M, Mizuki N, Itoh N, Okada E, Yoshida A, Xin KQ, Nishio O, Okuda K. Isolation and identification of adenovirus from conjunctival scrapings over a two-year period (between 2001 and 2003) in Yokohama, Japan. J Med Virol. 2007;79(2):200-205.
215. Hasumi Y, Inoko H, Mano S, Ota M, Okada E, Kulski JK, Nishizaki R, Mok J, Oka A, Kumagai N, Nishida T, Ohno S, Mizuki N. Analysis of single nucleotide polymorphisms at 13 loci within the transforming growth factor-induced factor gene shows no association with high myopia in Japanese subjects. Immunogenetics. 2006;58(12):947-953.
216. Chen X, Katoh Y, Nakamura K, Oyama N, Kaneko F, Endo Y, Fujita T, Nishida T, Mizuki N. Single nucleotide polymorphisms of Ficolin 2 gene in Behçet's disease. J Dermatol Sci. 2006;43(3):201-205.
217. Asukata Y, Ishihara M, Nakamura S, Hayashi K, Itoh Y, Takiyama N, Mizuki N. The reevaluation of categorization for ocular manifestation of sarcoidosis in the "Guidelines for Diagnosis of Ocular Sarcoidosis". Nippon Ganka Gakkai Zasshi. 2006;110(5):391-397.
218. Yanagihori H, Oyama N, Nakamura K, Mizuki N, Oguma K, Kaneko F. Role of IL-12B promoter polymorphism in Adamantiades-Behcet's disease susceptibility: An involvement of Th1 immunoreactivity against Streptococcus Sanguinis antigen. J Invest Dermatol. 2006;126(7):1534-1540.
219. Itoh Y, Mizuki N, Shimada T, Azuma F, Itakura M, Kashiwase K, Kikkawa E, Kulski JK, Satake M, Inoko H. High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics. 2005;57(10):717-729.
220. Kato Y, Saito H, Nishizaki R, Shiota T, Matsuda T, Mizuki N, Okada E. Contact lens user statistics in Okada eye clinic. Eye Contact Lens. 2005;31(5):231-237.
221. Saitou H, Kato Y, Nishizaki R, Shiota T, Matsuda T, Iyanaga K, Mizuki N, Okada E. An investigation of the actual conditions of use of daily-disposable soft contact lenses and two-week disposable soft contact lenses. Eye Contact Lens. 2005;31(5):225-320.
222. Mizuki N, Watanabe Y, Miyamoto M, Iijima Y, Takiyama N, Ito Y, Ito N, Nishida T, Iwata S, Endo Y, Ito D. Flomoxef sodium and levofloxacin concentrations in aqueous humor. Ocul Immunol Inflamm. 2005;13(2-3):229-234.
223. Kobayashi T, Sudo Y, Okamura S, Ohashi S, Urano F, Hosoi T, Segawa K, Mizuki N, Ota M. Monozygotic twins concordant for intestinal Behçet's disease. J Gastroenterol. 2005;40(4):421-425.
224. Teuchner B, Nagl M, Schidlbauer A, Ishiko H, Dragosits E, Ulmer H, Aoki K, Ohno S, Mizuki N, Gottardi W, Larcher C. Tolerability and efficacy of N-chlorotaurine in epidemic keratoconjunctivitis--a double-blind, randomized, phase-2 clinical trial. J Ocul Pharmacol Ther. 2005;21(2):157-165.
225. Yamaki K, Takiyama N, Itho N, Mizuki N, Seiya M, Sinsuke W, Hayakawa K, Kotani T. Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs. Exp Eye Res. 2005;80(2):273-280.
226. Mitani N, Aihara M, Yamakawa Y, Yamada M, Itoh N, Mizuki N, Ikezawa Z. Drug-induced hypersensitivity syndrome due to cyanamide associated with multiple reactivation of human herpesviruses. J Med Virol. 2005;75(3):430-434.
227. Wang H, Nakamura K, Inoue T, Yanagihori H, Kawakami Y, Hashimoto S, Oyama N, Kaneko F, Fujita T, Nishida T, Mizuki N. Mannose-binding lectin polymorphisms in patients with Behçet's disease. J Dermatol Sci. 2004;36(2):115-117.
228. Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Taylor AW. Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor. Int Immunopharmacol. 2004;4(8):1059-1066.
229. Yanagihori H, Tojo M, Inoue T, Nakamura K, Kaneko F, Nishida T, Mizuki N. Lack of association of interleukin-12 p40 gene (IL12B) polymorphism with Behçet's disease in the Japanese population. J Dermatol Sci. 2004;34(2):112-114.
230. Cheng Q, Sasaki Y, Shoji M, Sugiyama Y, Tanaka H, Nakayama T, Mizuki N, Nakamura F, Takei K, Goshima Y. Cdk5/p35 and Rho-kinase mediate ephrin-A5-induced signaling in retinal ganglion cells. Mol Cell Neurosci. 2003;24(3):632-645.
231. Ohgami K, Ilieva IB, Shiratori K, Isogai E, Yoshida K, Kotake S, Nishida T, Mizuki N, Ohno S. Effect of human cationic antimicrobial protein 18 Peptide on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 2003;44(10):4412-4418.
232. Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K, Ohno S. Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Invest Ophthalmol Vis Sci. 2003;44(6):2694-2701.
233. Nomura E, Sato M, Suemizu H, Watanabe T, Kimura T, Yabuki K, Goto K, Ito N, Mizuki N, Ohno S, Kimura M. Hyperkaratosis and leukocytosis in transgenic mice carrying MHC class I related gene B (MICB). Tissue Antigens. 2003;61(4):300-307.
234. Mizuki N, Yabuki K, Ota M, Katsuyama Y, Ando H, Nomura E, Funakoshi K, Davatchi F, Chams H, Nikbin B, Ghaderi AA, Ohno S, Inoko H. Analysis of microsatellite polymorphism around the HLA-B locus in Iranian patients with Behcet's disease.Tissue Antigens. 2002;60(5):396-399.
235. Mizuki N, Ota M, Katsuyama Y, Yabuki K, Ando H, Shiina T, Palimeris GD, Kaklamani E, Ohno S, Inoko H. Sequenced-based typing of HLA-B*51 alleles and the significant association of HLA-B*5101 and -B*5108 with Behçet's disease in Greek patients. Tissue Antigens. 2002;59(2):118-121.
236. Sano K, Yabuki K, Imagawa Y, Shiina T, Mizuki N, Ohno S, Kuiski JK, Inoko H. The absence of disease-specific polymorphisms within the HLA-B51 gene that is the susceptible locus for Behçet's disease. Tissue Antigens. 2001;58(2):77-82.
237. Seki SS, Sugimura K, Ota M, Matsuzawa J, Katsuyama Y, Ishizuka K, Mochizuki T, Suzuki K, Yoneyama O, Mizuki N, Honma T, Inoko H, Asakura H. Strafication analysis of MICA triplet repeat polymorphisms and HLA antigens associated with ulcerative colitis in Japanese. Tissue Antigens. 2001;58(2):71-76.
238. Yoshida M, Mizuki N, Okada E, Kokaze A, Sekine Y, Uchida Y, Harada N, Takashima Y. Age-specific prevalence of open-angle glaucoma among more than 60,000 asymptomatic Japanese population. J Clin Epidemiol. 2001;54(11):1151-1158.
239. Shina T, Suto Y, Kasai F, Shigrnari A, Takishima N, Kikkawa E, Iwata K, Kuwano Y, Kitamura Y, Matsuzawa Y, Sano K, Nogami M, Kawata H, Li S, Fukuzumi Y, Yamazaki M, Tashiro H, Tamiya G, Kohda A, Okumura K, Ikemura T, Soeda E, Mizuki N, Kimura M, Bahram S, Inoko H. Genomic anatomy of a premiar Major Histocompatibility Complex paralogous region on chromosome 1q21-22. Genome Res. 2001;11(5):789-802.
240. Ota M, Katsuyama Y, Kimura A, Tsuchiya K, Kondo M, Naruse T, Mizuki N, Itoh K, Sasazuki T, Inoko H. A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLAclass III region. Genomics. 2001;71(3):263-270.
241. Sugimura K, Ota M, Matsuzawa J, Katsuyama Y, Ishizuka K, Mochizuki T, Mizuki N, Seki S, Honma T, Inoko H. A cloase relationship of triplet repeat polymorphism in MHC class I chain-related gene A (MICA) to the disease susceptibility and behavior in ulcerative colitis. Tissue Antigens. 2001;57(1):9-14.
242. Mizuki N, Ota M, Katsuyama Y, Yabuki K, Ando H, Nikbin B, Davatchi F, Chams H, Ghaderi AA, Ohno S, Inoko H. HLA class I genotyping including HLA-B*51 allele typing in the Iranian patients with Behçet's disease. Tissue Antigens. 2001;57(5):457-462.
243. Mizuki N, Yabuki K, Ota M, Verity D, Katsuyama Y, Ando H, Goto K, Nomura E, Imagawa Y, Madanat W, Fayyad F, Stanford M, Ohno S, Inoko H. Microsatellite mapping of a susceptibility locus within the HLA region for Behçet's disease using Jordanian patients. Hum Immunol. 2001;62(2):186-190.
244. Mizuki N, Ota M, Katsuyama Y, Yabuki K, Ando H, Nomura E, Ohno S, Inoko H. HLA-B*51 allele analysis by the PCR-SBT method and a strong association of HLA-B*5101 with Japanese patients with Behçet's disease. Tissue Antigens. 2001;58(3):181-184.
245. Mizuki N, Ota M, Katsuyama Y, Ando H, Yabuki K, Goto k, Palimeris G, Kaklamani E, Pivetti-Pezzi P, Ohno S, Inoko H. Localization of the pathogenic gene of Behçet's disease onto the HLA-B locus by investigation of microsatellite polymorphism in three different populations. Invest Ophthalmol Visual Sci. 2000;41(12):3702-3708.
246. Kera J, Mizuki N, Ota M, katsuyama Y, Pivetti-Pezzi P, Ohno S, Inoko H. Significant associations of HLA-B*5101 and B*5108, and lack of association of class II alleles with Behçet's disease in Italian patients. Tissue Antigens. 1999;54(6):565-571.
247. Katsuyama Y, Ota M, Ando H, Saito S, Mizuki N, Kera J, Bahram S, Nose Y, Inoko H. Sequencing based typing for genetic polymorphisms in exon 2, 3 and 4 of the MICA gene. Tissue Antigens. 1999;54(2):178-184.
248. Yabuki K, Ohno S, Mizuki N, Ando H, Tabbara KF, Goto K, Nomura E, Nakamura S, Ito N, Ota M, Katsuyama Y, Inoko H. HLA class I and class II typing of the patients with Behçet's disease in Saudi Arabia. Tissue Antigens. 1999;54(3):273-277.
249. Wallace GR, Verity DH, Delamaine LJ, Ohno S, Inoko H, Ota M, Mizuki N, Yabuki K,Kondiatis E, Stephens HA, Madanat W, Kanawati CA, Stanford MR, Vaughan RW. MICA allele profiles and HLA class I associations in Behçet's disease. Immunogenetics. 1999;49(7-8):613-617.
250. Yabuki K, Mizuki N, Ota M, Katsuyama Y, Palimeris G, Stavropoulos C, Koumantaki Y, Spyropoulou M, Giziaki E, Kaklamani V, Kaklamani E, Inoko H, Ohno S. Association of MICA Gene and HLA-B*5101 with Behçet's disease in Greece. Invest Ophthalmol Visual Sci. 1999;40(9):1921-1926.
251. Ota M, Mizuki N, Katsuyama Y, Tamiya G, Takashi S, Oka A, Ando H, Kimura M, Goto K, Ohno S, Inoko H. The critical region for Behçet disease in the human major histo-compatibility complex is reduced to a 46-kb segment centromeric of HLA-B by association analysis using refined microsatellite mapping. Am J Hum Genet. 1999;64(5):1406-1410.
252. Yabuki K, Ota M, Goto K, Kimura M, Nomura E, Ohno S, Mizuki N, Katsuyama Y, Makysymowych WP, Bahram S, Kimura M, Inoko H. Triplet repeat polymorphism in the MICA gene in HLA-B27 positive and negative patients with ankylosing spondylitis. Hum Immunol. 1999;60(1):83-86.
253. Mizuki N, Ota M, Katsuyama Y, Ando H, Yabuki K, Goto K, Nakamura S, Ohno S, Inoko H. Association analysis between the MICA and HLA-B alleles in the Japanese patients with Behçet's disease. Arthritis Rheumatism. 1999;42(9):1961-1966.
254. Katsuyama Y, Inoko H, Imanishi T, Mizuki N, Gojobori T, Ota M. Genetic relationships among Japanese, northern Han, Hui, Uygur, Kazakh, Greek, Saudi Arabian, and Italian populations based on allelic frequencies at four VNTR (D1S80, D4S43, COL2A1, D17S5) and one STR (ACTBP2) loci. Hum Hered. 1998;48(3):126-137.
255. Kimura T, Goto K, Yabuki K, Mizuki N, Tamiya G, Sato M, Kimura M, Inoko H, Ohno S. Microsatellite polymorphism within the MICB gene among Japanese patients with Behçet's disease. Hum Immunol. 1998;59(8):500-502.
256. Goto K, Ota M, Maksymowych WP, Mizuki N, Yabuki K, Katsuyama Y, Kimura M, Inoko H, Ohno S. Association between MICA gene A4 allele and acute anterior uveitis in White patients with and without HLA-B27. Am J Ophthalmol. 1998;126(3):436-441.
257. Goto K, Ota M, Ando H, Mizuki N, Nakamura S, Inoue K, Yabuki K, Kotake S, Katsuyama Y, Kimura M, Inoko H, Ohno S. MICA gene polymorphisms and HLA-B27 subtypes in Japanese patients with HLA-B27-associated acute anterior uveitis. Invest Ophthalmol Vis Sci. 1998;39(3):634-637.
258. Shiina T, Tamiya G, Oka A, Yamagata T, Yamagata N, Kikkawa E, Goto K, Mizuki N, Watanabe K, Fukuzumi Y, Taguchi S, Sugawara C, Ono A, Chen L, Yamazaki M, TashiroH, Ando A, Ikemura T, Kimura M, Inoko H. Nucleotide sequencing analysis of the 146 kb segment around the IkBL and MICA genes at the centromeric end of the HLA class I region. Genomics. 1998;47(3):372-382.
259. Mizuki N, Ohno S, Ando H, Sato T, Imanishi T, Gojobori T, Ishihara M, Goto K, Ota M, Geng Z, Geng L, Li G, Inoko H. Major histocompatibility complex class II alleles in an Uygur population in the Silk Route of northwest China. Tissue Antigens. 1998;51(3):287-292.
260. Ishihara M, Ohno S, Ishida T, Naruse T, Kagiya M, Mizuki N, Naruya E, Saji H, Inoko H. Analysis of allelic variation of the TAP2 gene in sarcoidosis. Tissue Antigens. 1997;49(2):107-110.
261. Imai H, Motegi M, Mizuki N, Ohtani H, Komatsuda A, Hamai K, Miura AB. Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome): A case report and literature review. Am J Med Sci. 1997;314(5):330-332.
262. Ando H, Mizuki N, Ota M, Yamazaki M, Ohno S, Goto K, Miyata Y, Wakisaka K, Bahram S, Inoko H. Allelic variants of the human MHC class I-related B gene (MICB). Immunogenetics. 1997;46(6):499-508.
263. Goto K, Ota M, Ohno S, Mizuki N, Ando H, Katsuyama Y, Kimura M, Inoko H. Polymorphism in the MICA gene in the patients with ankylosing spondylitis. Tissue Antigens. 1997;49(5):503-507.
264. Ota M, Katsuyama K, Mizuki N, Ando H, Furihata K, Ono S, Pivetti-Pezzi P, Tabbara KF, Palimeris GP, Nikbin B, Davatchi F, Chams H, Geng Z, Bahram S, Inoko H. Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain- related gene A): Allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek, Italian. Tissue Antigens. 1997;49(5):448-454.
265. Ando H, Mizuki N, Ohno S, Tabbara KF, Taguchi S, Yamazaki M, Miyata Y, Wakisaka K, Inoko H. Identification of a novel HLA-B allele (B*4202) from a Saudi Arabian family with Behçet's disease. Tissue Antigens. 1997;49(5):526-528.
266. Mizuki N, Ohno S, Ando H, Sato T, Ishihara M, Imanishi T, Geng Z, Geng L, Li G, Inoko H. Major histocompatibility complex class II alleles in Kazak and Han populations in the Silk Route of northwest China. Tissue Antigens. 1997;50(5):527-534.
267. Mizuki N, Ohno S, Ando H, Palimeris GD, Stavropoulos-Gikas C, Ishihara M, Nakamura S, Isobe K, Shindo Y, Ito N, Inoko H. A strong association of HLA-B*5101 with Behçet's disease in Greek patients. Tissue Antigens. 1997;50(1):57-60.
268. Mizuki N, Ando H, Kimura M, Ohno S, Miyata S, Yamazaki M, Tashiro H, Watanabe K, Ono A, Taguchi S, Sugawara C, Fukuzumi Y, Okumura K, Goto K, Ishihara M, Nakamura S, Yonemoto J, Kikuti YY, Shiina T, Chen L, Ando A, Ikemura T, Inoko H. Nucleotide sequence analysis of the HLA class I region spanning the 237 kb segment around the HLA-B and -C genes. Genomics. 1997;42(1):55-66.
269. Mizuki N, Ota M, Kimura M, Ohno S, Ando H, Katsuyama Y, Yamazaki M, Watanabe K, Goto K, Nakamura S, Bahram S, Inoko H. Triplet repeat polymorphism in the transmembrane region of the MICA gene: A strong association of six GCT repetitions with Behçet's disease. Proc Natl Acad Sci U S A. 1997;94(4):1298-1303.
270. Ishihara M, Yamagata N, Ohno S, Naruse T, Ando A, Kawata H, Ozawa A, Ohkido M, Mizuki N, Shiina T, Ando H, Inoko H. Genetic polymorphisms in the keratin-like S gene within the human major histocompatibility complex and association analysis on the susceptibility to psoriasis vulgaris. Tissue Antigens. 1996;48(3):182-186.
271. Fodil N, Laloux L, Wanner V, Pellet P, Hauptmann G, Mizuki N, Inoko H, Spies T, Theodorou I, Bahram S. Allelic repertoire of the human MHC class I MICA gene. Immunogenetics. 1996;44(5):351-357.
272. Ishihara M, Naruse T, Ohno S, Kawata H, Mizuki N, Yamagata N, Ishida T, Nose Y, Inoko H. Analysis of HLA-DM polymorphisms in sarcoidosis. Hum Immunol. 1996;49(2):144-146.
273. Ishihara M, Ohno S, Mizuki N, Yamagata N, Ishida T, Naruse T, Ando A, Inoko H. LMP7 polymorphism in Japanese patients with sarcoidosis and Behçet's disease. Hum Immunol. 1996;51(2):103-105.
274. Ishihara M, Ohno S, Mizuki N, Yamagata N, Naruse T, Shiina T, Kawata H, Kuwata S, Inoko H. Allelic variations in the TAP2 and LMP2 genes in Behçet's disease. Tissue Antigens. 1996;47(3):249-252.
275. Ishihara M, Ohno S, Mizuki N, Yamagata N, Ishida T, Naruse T, Kawata S, Inoko H. Genetic polymorphisms of the MHC-encoded antigen processing gene (TAP, LMP) in sarcoidosis. Hum Immunol. 1996;45(2):105-110.
276. Inoko H, Mizuki N, Shiina T, Ando A, Kimura M, Kikuchi YY, Kawata H, Sugaya K, Fukagawa T, Matsumoto K, Nagata T, Taketo M, Okumura K, Kasahara M, Ikemura T: Cloning, sequencing and evolutionary analyses of the human major histocompatibility complex (MHC) region. DNA Seq. 1996;7(1):31-32.
277. Bahram S, Mizuki N, Inoko H, Spies T. Nucleotide sequence of the human MHC class I MICA gene. Immunogenetics. 1996;44(1):80-81.
278. Ando H, Mizuki N, Ando R, Miyata Y, Miyata S, Wakisaka K, Inoko H. HLA-C genotyping in the Japanese population by the PCR-SSP method. Tissue Antigens. 1996;48(1):55-58.
279. Mizuki N, Inoko H, Ando H, Kiyosawa K, Seki T, Geng Z, Geng L, Li G, Ishihara M, Shindo Y, Onishi H, Onoe K, Ohno S. Seroepidemiological studies on Silk Route ethnic groups. Tokai Exp Clin Med. 1996;21(3):117-120.
280. Mizuki N, Ando H, Ohno S, Kimura M, Ishihara M, Miyata S, Nakamura S, Mizuki N, Inoko H. HLA-C genotyping of patients with Behçet's disease in the Japanese population. Hum Immunol. 1996;50(1):47-53.
281. Mizuki N, Kimura M, Ohno S, Miyata S, Sato M, Ishihara M, Ono A, Taguchi S, Yamazaki M, Ando H, Okumura K, Nogami M, Taguchi H, Ando A, Inoko H. Isolation of cDNA and genomic clones of a human ras-related GTP-binding protein (Rheb) and its chromosomal localization to the long arm of chromosome 7, 7q36. Genomics. 1996;34(1):114-118.
282. Geng L, Imanishi T, Tokunaga K, Zhu D, Mizuki N, Xu S, Geng Z Gojobori T, Tsuji K, Inoko H. Determination of HLA class II alleles by genotyping in a Manchu population in the northern part of China and its relationship with Han and Japanese populations. Tissue Antigens. 1995;46(2):111-116.
283. Ishihara M, Ohno S, Ishida T, Mizuki N, Ando H, Naruse T, Inoko H. Genetic polymorphisms of the TNFB and HSP70 genes located in the human major histocompatibility complex in sarcoidosis. Tissue Antigens. 1995;46(1):59-62.
284. Ishihara M, Ishida T, Mizuki N, Inoko H, Ando H, Ohno S. Clinical features of sarcoidosis in relation to HLA distribution and HLA-DRB3 genotyping by PCR-RFLP. Br J Ophthalmol. 1995;79(4):322-325.
285. Mizuki N, Ohno S, Sato T, Ishihara M, Miyata S, Nakamura S, Naruse T, Mizuki H, Tsuji K, Inoko H. Microsatellite polymorphism located between the TNF and HLA-B genes in Behçet's disease. Hum Immunol. 1995;43(2):129-135.
286. Ishihara M, Ishida T, Mizuki N, Inoko H, Kagiya M, Ando H, Ohno S. A case study of sibling relationship in sarcoidosis by HLA-DNA genotyping. Graef Arch Clin Exp Ophthalmol. 1994;232(12):761-762.
287. Niizeki H, Inoko H, Mizuki N, Inamoto N, Watanabe K, Hashimoto T, Nishikawa T. HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris by PCR-RFLP method. Tissue Antigens. 1994;44(4):248-251.
288. Mizuki N, Inoko H, Ishihara M, Ando H, Nakamura S, Nishio M, Ohno S. A complete type patient with Behçet's disease associated with HLA-B*5102. Acta Ophthalmologica. 1994;72(6): 757-758.
289. Seki T, Kiyosawa K, Ota M, Fukushima H, Tanaka E, Yoshizawa K, Furuta S, Kumagai T, Mizuki N, Ando A, Inoko H. Association of primary biliary cirrhosis with human leukocyte antigen-DPB1*0501 in Japanese. Hepatology 1993;18(1):73-78.
290. Sugimura K, Asakura H, Mizuki N, Inoue M, Hibi T, Yagita A, Tsuji K, Inoko H. Analysis of genes within the HLA region affecting susceptibility to Ulcerative Colitis. Hum Immunol. 1993;36(2):112-118.
291. Mizuki N, Inoko H, Ando H, Nakamura S, Kashiwae K, Akaza T, Fujino Y, Masuda K, Takiguchi M, Ohno S. Behçet's disease associated with one of the HLA-B51 subantigens, HLA-B*5101. Am J Ophthalmol. 1993;116(4):406-409.
292. Mizuki N, Ohno S, Sugimura K, Seki T, Mizuki N, Ishioka M, Inoko H. Identification of a new HLA-DPB1 allele detected by PCR-RFLP and its nucleotide sequence determination by direct sequencing after PCR amplification. Tissue Antigens. 1993;41(5):259-262.
293. Seki T, Ota M, Furuta S, Fukushima H, Kondo T, Hino K, Mizuki N, Ando A, Tsuji K,Inoko H, Kiyosawa K. HLA class II molecules associated autoimmune hepatitis susceptibility in Japanese patients. Gastroenterology. 1992;103(3):1041-1047.
294. Mizuki N, Ohno S, Nakamura S, Mizuki N, Mizuki H, Sugimura K, Tanaka H, Kera J, Tsuji K, Inoko H. Searching for the gene(s) within the HLA region responsible for the susceptibility to Behçet's disease. Chibret Int J Ophthalmol. 1992;9:10-24.
295. Mizuki N, Inoko H, Sugimura K, Nishimura K, Nakamura S, Tanaka H, Mizuki N, Mizuki H, Inaba G, Tsuji K, Ohno S. RFLP analysis in the TNFβgene and the susceptibility to NK cells in Behçet's disease. Invest Ophthalmol Vis Sci. 1992;33(11):3084-3090.
296. Mizuki N, Inoko H, Mizuki N, Tanaka H, Kera J, Tsuji K, Ohno S. Human leukocyte antigen serologic and DNA typing of Behçet's disease and its primary association with B51. Invest Ophthalmol Vis Sci. 1992;33(12):3332-3340.
297. Mizuki N, Ohno S, Sugimura K, Seki T, Kikuti YY, Ando A, Tsuji K, Inoko H. PCR-RFLP is as sensitive and reliable as PCR-SSO in HLA class II genotyping. Tissue Antigens. 1992;40(2):100-103.
298. Mizuki N, Ohno S, Tanaka H, Sugimura K, Seki T, Ando A, Kera J, Inaba G, Tsuji K, Inoko H. Association of HLA-B51 and lack of association of class II alleles with Behçet's disease. Tissue Antigens. 1992;40(1):22-30.
299. Ota M, Seki T, Nomura N, Sugimura K, Mizuki N, Fukushima H, Tsuji K, Inoko H. Modifie PCR-RFLP method for HLA DPB1 and -DQA1 genotyping. Tissue Antigenes. 1991;38(2):60-71.

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