研究実績

主な発表論文

2025年度

1. Kuroda H, Yeung SLA, Fujii R, Iwagami M, Goto A. Investigating the non-linear association between sleep duration and type 2 diabetes: conventional and Mendelian randomization analyses from the UK Biobank. J Diabetes Investig. 2025 Jun;16(6):1126-1137.
2. Suzuki Y, Honjo K, Iso H, Yamagishi K, Muraki I, Sakata K, Tanno K, Yasuda N, Saito I, Kato T, Arima K, Nakashima H, Yamaji T, Iwasaki M, Inoue M, Goto A, Sawada N, Tsugane S. Association between the number of social roles and self-rated health: mediation effect by ikigai and the size of close social networks. J Epidemiol Community Health. 2025 Jun 11;79(7):491-497.
3. Kuwahara K, Yamamoto S, Honda T, Nakagawa T, Konishi M, Mizoue T. Trajectories of healthy lifestyle index and prediabetes risk of adult workers in Japan. Commun Med (Lond). 2025 Jun 20;5(1):240.
4. Nakayama I, Goto A, Yamaji T, Iwasaki M, Inoue M, Tsugane S, Sawada N. Coffee Consumption and Risk of Esophageal Squamous Cell Carcinoma: A Population-Based Prospective Cohort Study in Japan. J Nutr. 2025 Jun 20:S0022-3166(25)00370-0.

2024年度

1. Xu J, Goto A, Konishi M, Kato M, Mizoue T, Terauchi Y, Tsugane S, Sawada N, Noda M. Development and Validation of Prediction Models for the 5-year Risk of Type 2 Diabetes in a Japanese Population: Japan Public Health Center-based Prospective (JPHC) Diabetes Study. J Epidemiol. 2024 Apr 5;34(4):170-179.
2. Yoshida T, Goto A, Shinoda S, Kotani Y, Mihara T; BROTHER study group. The epidemiology of postoperative dobutamine and phosphodiesterase inhibitors after adult elective cardiac surgery and its impact on the length of hospital stay: a post hoc analysis from the multicenter retrospective observational study. Heart Vessels. 2024 May;39(5):438-445.
3. Zhang E, Chen J, Liu Y, Li H, Li Y, Kuwahara K, Xiang M. Associations between joint lifestyle behaviors and depression among children and adolescents: A large cross-sectional study in China. J Affect Disord. 2024 May 1;352:110-114.
4. Minoura A, Shimada Y, Kuwahara K, Kondo M, Fukushima H, Sugiyama T. Medical researchers' perceptions regarding research evaluation: a web-based survey in Japan. BMJ Open. 2024 May 8;14(5):e079269.
5. Orihara S, Goto A, Taguri M. Valid instrumental variable selection method using negative control outcomes and constructing efficient estimator. Biom J. 2024 Jun;66(4):e2300113.
6. Kaneko M, Shinoda S, Nakayama I, Xu J, Yagome S, Goto A. Usual source and better quality of primary care are associated with lower loneliness scores: a cross-sectional study. Fam Pract. 2024 Jun 12;41(3):312-320.
7. Kuwahara K, Ohkubo T, Inoue Y, Honda T, Yamamoto S, Nakagawa T, Okazaki H, Yamamoto M, Miyamoto T, Gommori N, Kochi T, Ogasawara T, Yamamoto K, Konishi M, Kabe I, Dohi S, Mizoue T. Blood pressure classification using the Japanese Society of Hypertension Guidelines for the Management of Hypertension and cardiovascular events among young to middle-aged working adults. Hypertens Res. 2024 Jul;47(7):1861-1870.
8. Okubo Y, Ishitsuka K, Goto A. Impact of COVID-19 pandemic on physical health amongst children: Difference-in-differences analyses of nationwide school health checkup database. Pediatr Obes. 2024 Jul;19(7):e13126.
9. Yagome S, Ohsugi M, Sugiyama T, Bouchi R, Goto A, Ueki K. Trends in prescription days and intervals between physician visits and their impact on glycemic control before and during the COVID-19 pandemic in Japan. GHM Open. 2024 Jul 31;4(1):18-22.
10. Inoue K, Naito T, Fuji R, Sonehara K, Yamamoto K, Baba R, Kodama T, Otagaki Y, Okada A, Itcho K, Kobuke K, Ohno H; BioBank Japan; Morisaki T, Hattori N, Goto A, Nishikawa T, Oki K, Okada Y. Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome-Wide Association and Mendelian Randomization Study. J Am Heart Assoc. 2024 Aug 6;13(15):e034180.
11. Iwagami M, Inokuchi R, Kawakami E, Yamada T, Goto A, Kuno T, Hashimoto Y, Michihata N, Goto T, Shinozaki T, Sun Y, Taniguchi Y, Komiyama J, Uda K, Abe T, Tamiya N. Comparison of machine-learning and logistic regression models for prediction of 30-day unplanned readmission in electronic health records: A development and validation study. PLOS Digit Health. 2024 Aug 20;3(8):e0000578.
12. Ihana-Sugiyama N, Sano K, Sugiyama T, Goto A, Hirata T, Ueki K, Tsushita K. Evaluation of a program designed to prevent diabetic nephropathy aggravation: A retrospective cohort study using health checkups and claims data in Japanese municipalities. Diabetes Res Clin Pract. 2024 Sep;215:111804.
13. Li C, Bishop TRP, Imamura F et al. Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries. Lancet Diabetes Endocrinol. 2024 Sep;12(9):619-630.
14. Kihara T, Yamagishi K, Imatoh T, Ihira H, Goto A, Iso H, Sawada N, Tsugane S, Inoue M. Validity of Self-reported Helicobacter pylori Eradication Treatment From Questionnaire and Interview Surveys of the JPHC-NEXT Study: Comparison With Prescription History From Insurance Claims Data. J Epidemiol. 2024 Sep 5;34(9):453-457.
15. Hishida A, Nakatochi M, Sutoh Y, Nakano S, Momozawa Y, Narita A, Tanno K, Shimizu A, Hozawa A, Kinoshita K, Yamaji T, Goto A, Noda M, Sawada N, Ikezaki H, Nagayoshi M, Hara M, Suzuki S, Koyama T, Koriyama C, Katsuura-Kamano S, Kadota A, Kuriki K, Yamamoto M, Sasaki M, Iwasaki M, Matsuo K, Wakai K. GWAS Meta-analysis of Kidney Function Traits in Japanese Populations. J Epidemiol. 2024 Nov 5;34(11):526-534.
16. Nishihara K, Nakano S, Yamaji T, Goto A, Hidaka A, Shimazu T, Kuchiba A, Saito M, Kunishima F, Nakaza R, Kato I, Sawada N, Inoue M, Tsugane S, Iwasaki M; Japan Public Health Center‐based Prospective Study Group. Height, body mass index, physical activity, and risk of colorectal cancer in relation to expression of insulin receptor: The Japan Public Health Center-based Prospective Study. Int J Cancer. 2024 Nov 15;155(10):1751-1761.
17. Suzuki Y, Iwagami M, Shimizu S, Goto A. Effects of incentivising dialysis facilities on peripheral arterial disease care in patients undergoing haemodialysis: a claims-based cohort study. Clin Kidney J. 2024 Nov 18;17(12):sfae342.
18. Taguri M, Kuchiba A, Yamaji T, Sawada N, Goto A, Iwasaki M, Tsugane S. Importance of Circulating Leptin and Adiponectin in the Causal Pathways Between Obesity and the Development of Colorectal Cancer in Japanese Men. J Epidemiol. 2024 Dec 5;34(12):563-569.
19. Saito K, Kawai Y, Ishikawa H, Tabuchi T, Kuwahara K. Combined associations of education and health literacy with preventive dental visits in patients with diabetes: a nationwide cross-sectional study. Diabetol Int. 2024 Dec 2;16(1):145-152.
20. Yeung SLA, Luo S, Iwagami M, Goto A. Introduction to Mendelian randomization. Ann Clin Epidemiol. 2025 Jan 1;7(1):27-37.
21. Orihara S, Goto A. Comparison of Instrumental Variable Methods With Continuous Exposure and Binary Outcome: A Simulation Study. J Epidemiol. 2025 Jan 5;35(1):11-20.
22. Inoue K, Sakamaki K, Komukai S, Ito Y, Goto A, Shinozaki T. Methodological Tutorial Series for Epidemiological Studies: Confounder Selection and Sensitivity Analyses to Unmeasured Confounding From Epidemiological and Statistical Perspectives. J Epidemiol. 2025 Jan 5;35(1):3-10.
23. Omura T, Goto A, Nakayama I, Saito J, Noda M, Yasuda N, Saito I, Kato T, Arima K, Kawakami F, Sakata K, Tanno K, Yamaji T, Iwasaki M, Yamagishi K, Iso H, Inoue M, Tsugane S, Sawada N. Socioeconomic Status and Diabetes Prevalence in the Japanese: Insights From the JPHC-NEXT Study. Mayo Clin Proc. 2025 Mar;100(3):452-464.
24. Takachi R, Yamagishi M, Goto A, Inoue M, Yamaji T, Iwasaki M, Yamagishi K, Iso H, Tsugane S, Sawada N; JPHC Study Group. Consumption of Sodium and Its Ratio to Potassium in Relation to All-Cause, Cause-Specific, and Premature Noncommunicable Disease Mortality in Middle-Aged Japanese Adults: A Prospective Cohort Study. J Nutr. 2025 Mar;155(3):945-956.

2023年度

1. Kanehara R, Goto A, Goto M, Takahashi T, Iwasaki M, Noda M, Ihira H, Tsugane S, Sawada N. Validation Study of Diabetes Definitions Using Japanese Diagnosis Procedure Combination Data Among Hospitalized Patients. J Epidemiol. 2023 Apr 5;33(4):165-169.
2. Kuwahara K, Kato M, Ishikawa H, Shinozaki T, Tabuchi T. Association between watching wide show as a reliable COVID-19 information source and preventive behaviors: A nationwide survey in Japan. PLoS One. 2023 Apr 11;18(4):e0284371.
3. Goto A, Miyakawa K, Nakayama I, Yagome S, Xu J, Kaneko M, Ohtake N, Kato H, Ryo A. Prediction models for neutralization activity against emerging SARS-CoV-2 variants: A cross-sectional study. Front Microbiol. 2023 Apr 11;14:1126527.
4. Hanyuda A, Goto A, Katagiri R, Koyanagi YN, Nakatochi M, Sutoh Y, Nakano S, Oze I, Ito H, Yamaji T, Sawada N, Iwagami M, Kadota A, Koyama T, Katsuura-Kamano S, Ikezaki H, Tanaka K, Takezaki T, Imoto I, Suzuki M, Momozawa Y, Takeuchi K, Narita A, Hozawa A, Kinoshita K, Shimizu A, Tanno K, Matsuo K, Tsugane S, Wakai K, Sasaki M, Yamamoto M, Iwasaki M. Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation. Sci Rep. 2023 Apr 29;13(1):7052.
5. Miyamoto Y, Katagiri R, Yamaji T, Inoue M, Goto A, Iwasaki M, Noda M, Tsugane S, Sawada N. Association of chronic kidney disease with total and site-specific cancer incidence in participants of the Japan Public Health Center-based Prospective Study. Nephrol Dial Transplant. 2023 May 31;38(6):1487-1496.
6. Kanehara R, Katagiri R, Goto A, Yamaji T, Sawada N, Iwasaki M, Inoue M, Tsugane S; JPHC Study Group. Sugar intake and colorectal cancer risk: A prospective Japanese cohort study. Cancer Sci. 2023 Jun;114(6):2584-2595.
7. Miki T, Nanri A, Mizoue T, Goto A, Noda M, Sawada N, Tsugane S. Association of body mass index and weight change with pneumonia mortality in a Japanese population: Japan Public Health Center-based Prospective Study. Int J Obes (Lond). 2023 Jun;47(6):479-486.
8. Hoang DV, Akter S, Inoue Y, Kuwahara K, Fukunaga A, Islam Z, Nakagawa T, Honda T, Yamamoto S, Okazaki H, Miyamoto T, Ogasawara T, Sasaki N, Uehara A, Yamamoto M, Kochi T, Eguchi M, Shirasaka T, Shimizu M, Nagahama S, Hori A, Imai T, Nishihara A, Tomita K, Nishiura C, Konishi M, Kabe I, Yamamoto K, Mizoue T, Dohi S. Metabolic Syndrome and the Increased Risk of Medically Certified Long-term Sickness Absence: A Prospective Analysis Among Japanese Workers. J Epidemiol. 2023 Jun 5;33(6):311-320.
9. Fukuda N, Horita N, Kaneko A, Goto A, Kaneko T, Ota E, Kew KM. Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2023 Jun 5;6(6):CD012066.
10. Bouchi R, Noda M, Hayashino Y, Goto A, Yamazaki K, Suzuki H, Furukawa TA, Izumi K, Kobayashi M; J-DOIT2 Study Group. Behavioral change stage might moderate the impact of multifaceted interventions on non-attendance from medical care among patients with type 2 diabetes: The Japan Diabetes Outcome Intervention Trial-2 Large-Scale Trial 007 (J-DOIT2-LT007). J Diabetes Investig. 2023 Jul;14(7):907-916.
11. Goto A, Katanoda K. Should We Acknowledge ChatGPT as an Author? J Epidemiol. 2023 Jul 5;33(7):333-334.
12. Arakawa Y, Inoue K, Nishioka D, Nakagomi A, Tabuchi T, Kondo N. Remote Communication and Loneliness During the COVID-19 Pandemic: Cross-Sectional Study. J Med Internet Res. 2023 Jul 11;25:e45338.
13. Arakawa Y, Haseda M, Inoue K, Nishioka D, Kino S, Nishi D, Hashimoto H, Kondo N. Effectiveness of mHealth consultation services for preventing postpartum depressive symptoms: a randomized clinical trial. BMC Med. 2023 Jun 26;21(1):221.
14. Nakayama I, Izawa J, Gibo K, Murakami S, Akiyama T, Kotani Y, Katsurai R, Kishihara Y, Tsuchida T, Takakura S, Takayama Y, Narita M, Shiiki S. Contamination of Blood Cultures From Arterial Catheters and Peripheral Venipuncture in Critically Ill Patients: A Prospective Multicenter Diagnostic Study. Chest. 2023 Jul;164(1):90-100.
15. Fujii K, Nakayama I, Izawa J, Iida N, Seo Y, Yamamoto M, Uenishi N, Terasawa T, Iwata M. Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: a prospective, exploratory observational study. Crit Care. 2023 Jul 10;27(1):278.
16. Bouchi R, Sugiyama T, Goto A, Ohsugi M, Yoshioka N, Katagiri H, Mita T, Hirota Y, Ikegami H, Matsuhisa M, Araki E, Yokoyama H, Minami M, Yamazaki K, Jinnouchi H, Ikeda H, Fujii H, Nogawa M, Kaneshige M, Miyo K, Ueki K. Impact of COVID-19 pandemic on behavioral changes and glycemic control and a survey of telemedicine in patients with diabetes: A multicenter retrospective observational study. J Diabetes Investig. 2023 Aug;14(8):994-1004.
17. Saito E, Tanaka S, Abe SK, Hirayabashi M, Ishihara J, Katanoda K, Lin Y, Nagata C, Sawada N, Takachi R, Goto A, Tanaka J, Ueda K, Hori M, Matsuda T, Inoue M. Economic burden of cancer attributable to modifiable risk factors in Japan. Glob Health Med. 2023 Aug 31;5(4):238-245.
18. Katsuragawa S, Goto A, Shinoda S, Inoue K, Nakai K, Saito J, Nishikawa T, Tsurutani Y. Association of Reversal of Renin Suppression With Long-Term Renal Outcome in Medically Treated Primary Aldosteronism. Hypertension. 2023 Sep;80(9):1909-1920.
19. Kuwahara K, Sakamoto M, Ishizuka R, Kato M, Akiyama M, Ishikawa H, Kiyohara K. Effect of digital messages from health professionals on COVID-19-related outcomes: A systematic review of randomized controlled trials. J Infect Public Health. 2023 Oct;16(10):1682-1689.
20. Koyanagi et al. Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people. Sci Adv. 2024 Jan 26;10(4):eade2780.
21. Kuwahara K, Amagasa S, Yamaoka K. Declines in Physical Activity and Cardiorespiratory Fitness After Implementing new National School Guidelines. J Adolesc Health. 2024 Feb;74(2):385-387.
22. Goto A, Ohashi K, Noda M, Noto H, Ueki K, Inoue M, Nishimura R, Takahashi S, Ioka T, Oshima M, Fujibayashi K, Tsuji A, Kodaira M, Tamakoshi A, Mimori K, Tanabe Y, Hara E, Matsuo K, Murakami Y, Watada H. Third Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer: Summary of the results of a questionnaire survey of oncologists and diabetologists-Secondary publication. Cancer Sci. 2024 Feb;115(2):672-681.
23. Kikuchi H, Inoue S, Amagasa S, Kuwahara K, Ihira H, Inoue M, Iso H, Tsugane S, Sawada N. Relationships of Total and Domain-Specific Moderate-to-Vigorous Physical Activity with All-Cause and Disease-Specific Mortality. Med Sci Sports Exerc. 2024 Mar 1;56(3):520-527.

2022年度

1. Hanyuda A, Goto A, Nakatochi M, et al. Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population. Am J Ophthalmol. 2023 Jan;245:193-201.
2. Iwagami M, Goto A, Katagiri R, et al. Blood Lipids and the Risk of Colorectal Cancer: Mendelian Randomization Analyses in the Japanese Consortium of Genetic Epidemiology Studies. Cancer Prev Res (Phila). 2022 Dec 1;15(12):827-836.
3. Sahashi Y, Goto A, Takachi R, et al. Inverse Association between Fruit and Vegetable Intake and All-Cause Mortality: Japan Public Health Center-Based Prospective Study. J Nutr. 2022 Oct 6;152(10):2245-2254.
4. Yagome S, Sugiyama T, Inoue K, et al. Influence of the COVID-19 Pandemic on Overall Physician Visits and Telemedicine Use Among Patients With Type 1 or Type 2 Diabetes in Japan. J Epidemiol. 2022 Oct 5;32(10):476-482.
5. Nakayama I, Goto A, Hayashino Y, et al. Employment status and diabetic outpatient appointment non-attendance in middle to senior working generation with type 2 diabetes: the Japan diabetes outcome intervention trial-2 large‑scale trial 005 (J-DOIT2-LT005). Acta Diabetol. 2022 Jun;59(6):793-801.
6. Nanri A, Mizoue T, Goto A, Noda M, Sawada N, Tsugane S; Japan Public Health Center-based Prospective Study Group. Vitamin D intake and all-cause and cause-specific mortality in Japanese men and women: the Japan Public Health Center-based prospective study. Eur J Epidemiol. 2023 Mar;38(3):291-300.