研究業績

2024

原著論文

1. Murakami Y, Katsuchi D, Matsumoto T, Kanazawa K, Shibata T, Kawahara A, Akiba J, Yanaihara N, Okamoto A, Itamochi H, Sugiyama T, Terada A, Nishio S, Tsuda N, Kato K, Ono M, Kuwano M., Y-box binding protein 1/cyclin A1 axis specifically promotes cell cycle progression at G₂/M phase in ovarian cancer. Sci Rep., 14(1):21701, 2024.
2. Saito S, Cao DY, Shibata T, Liu Y, Otagiri-Hoshi A, Cui X, Bernstein KE., Tumor derived cell-free nucleic acid upregulates programmed death-ligand 1 expression in neutrophil via intracellular Toll-like receptor signaling. Cancer Commun., in press.
3. Bernstein KE, Cao DY, Shibata T, Saito S, Bernstein EA, Nishi E, Yamashita M, Tourtellotte WG, Zhao TV, Khan Z., Classical and nonclassical effects of angiotensin-converting enzyme: How increased ACE enhances myeloid immune function. J Biol Chem., 300(6):107388, 2024.
4. Tajika R, Masukawa D, Arai M, Nawa H, Goshima Y., Opposite regulation by L-DOPA receptor GPR143 of the long and short forms of the dopamine D2 receptors. J. Pharmacol Sci., 156(1):77-81, 2024.
5. Inoue M, Masukawa D, Goshima Y., L-DOPA receptor GPR143 inhibits neurite outgrowth via L-type calcium channels in PC12 cells. J. Pharmacol Sci., 156(1):45-48, 2024.
6. Arai M, Suzuki E, Kitamura S, Otaki M, Kanai K, Yamasaki M, Watanabe M, Kambe Y, Murata K, Takada Y, Arisawa T, Kobayashi K, Tajika R, Miyazaki T, Yamaguchi M, Lazarus M, Hayashi Y, Itohara S, d’Exaerde AK, Nawa H, Kim R, Bito H, Momiyama T, Masukawa D, Goshima Y., Enhancement of haloperidol-induced catalepsy by GPR143, an L-DOPA receptor, in striatal cholinergic interneurons. J Neurosci., 44(11):1504-1523. 2024.

学会発表

1. 増川太輝、柴田智博、吉田光一、増田拓、徳留健、中枢神経系における心房性ナトリウム利尿ペプチドシグナルは心筋梗塞モデルの病態を改善する、第151回薬理学会関東部会、2024年10月12日、O-4-15
2. 柴田智博、増川太輝、吉田光一、徳留健、心房性ナトリウム利尿ペプチドは腫瘍内血管の正常化を誘導する、第151回薬理学会関東部会、2024年10月12日、O-4-14
3. 赤坂灯香、程 晨、柴田智博、吉田光一、増田 拓、増川太輝、徳留 健、脳内アンジオテンシンⅡシグナルは交感神経活性化と心肥大を促進する、第151回薬理学会関東部会、2024年10月12日、O-4-01
4. 徳留健、ペプチドホルモンのトランスレーショナルリサーチと創薬、第150回薬理学会関東部会、2024年6月29日、教育講演3

2023

原著論文

1. Masukawa D, Takahagi R, Nakao Y, Goshima Y., L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α_1B Receptor at the Second Transmembrane Interface. Biol. Pharm. Bull., 46(7):869-873, 2023.
2. Sugioka S, Yamada H, Ishii A, Kato Y, Yamada R, Mori KP, Ohno S, Handa T, Ikushima A, Ishimura T, Osaki K, Tokudome T, Matsusaka T, Nebreda AR, Yanagita M, Yokoi H., Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi. Kidney Int., S0085-2538(23)00425-8, 2023.
3. Uchimura H, Kanai K, Arai M, Inoue M, Hishimoto A, Masukawa D, Goshima Y., Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate. J. Pharmacol. Sci., 165(2):177-195, 2023.
4. Masukawa D, Kitamura S, Tajika R, Uchimura H, Arai M, Takada Y, Arisawa T, Otaki M, Kanai K, Kobayashi K, Miyazaki T, Goshima Y., Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum. J. Neurochem., 165(2):177-195, 2023.