/* Box sizing rules */
*,
*::before,
*::after {
  box-sizing: border-box;
}

/* Remove default margin */
body,
h1,
h2,
h3,
h4,
p,
figure,
blockquote,
dl,
dd {
  margin: 0;
}

/* Remove list styles on ul, ol elements with a list role, which suggests default styling will be removed */
ul[role=list],
ol[role=list] {
  list-style: none;
}

/* Set core root defaults */
html:focus-within {
  scroll-behavior: smooth;
}

/* Set core body defaults */
body {
  min-height: 100vh;
  text-rendering: optimizeSpeed;
  line-height: 1.5;
}

/* A elements that don't have a class get default styles */
a:not([class]) {
  text-decoration-skip-ink: auto;
}

/* Make images easier to work with */
img,
picture {
  max-width: 100%;
  display: block;
}

/* Inherit fonts for inputs and buttons */
input,
button,
textarea,
select {
  font: inherit;
}

/* Remove all animations and transitions for people that prefer not to see them */
@media (prefers-reduced-motion: reduce) {
  html:focus-within {
    scroll-behavior: auto;
  }
  *,
  *::before,
  *::after {
    animation-duration: 0.01ms !important;
    animation-iteration-count: 1 !important;
    transition-duration: 0.01ms !important;
    scroll-behavior: auto !important;
  }
}
:root {
  --gray0: #ffffff;
  --gray100: #F9FAFC;
  --gray200: #E2E5ED;
  --gray300: #BEC2CC;
  --gray400: #9196A4;
  --gray600: #555D70;
  --gray900: #293248;
  --blue600: #008ce7;
  --breakpoint-lg: 928px;
}

.global-header {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 1rem 2.5rem;
}
@media screen and (max-width: 928px) {
  .global-header {
    display: none;
  }
}

.navigation {
  display: flex;
}

.navigation__item {
  border-bottom: 3px solid var(--gray0);
}
.navigation__item.active {
  border-bottom: 3px solid var(--blue600);
}
.navigation__item:hover {
  border-bottom: 3px solid var(--blue600);
  transition: border-bottom 0.3s ease-out;
}
.navigation__item a {
  display: inline-block;
  padding: 15px 16px 14px 16px;
  text-decoration: none;
  color: var(--gray600);
}

.mobile-header {
  display: none;
  position: relative;
  padding: 1rem 1.5rem 0.5rem 1rem;
}
@media screen and (max-width: 928px) {
  .mobile-header {
    display: flex;
    justify-content: flex-end;
  }
}
.mobile-header .nav-toggle {
  width: 40px;
  height: 40px;
}
.mobile-header .nav-backdrop {
  position: fixed;
  top: 0;
  right: 0;
  bottom: 0;
  left: 0;
  background-color: rgba(0, 0, 0, 0.8);
  display: none;
}
.mobile-header .nav-backdrop.active {
  display: block;
  z-index: 15;
}
.mobile-header .nav-item-list {
  width: 80vw;
  background-color: #fff;
  z-index: 20;
  position: fixed;
  top: 0;
  bottom: 0;
  right: -80vw;
  transition: all 0.3s ease;
}
.mobile-header .nav-item-list.active {
  right: 0;
}
.mobile-header .nav-item {
  font-size: 1rem;
  border-left: 5px solid var(--gray0);
}
.mobile-header .nav-item:last-of-type {
  border-bottom: 0;
}
.mobile-header .nav-item a {
  color: var(--gray600);
  padding: 1em 1.25em;
  text-decoration: none;
  display: block;
}
.mobile-header .nav-item.brand {
  width: 100%;
  border-bottom: 1px solid var(--gray200);
  padding: 1rem 0;
  margin-bottom: 1rem;
}
.mobile-header .nav-item.close a {
  color: var(--gray400);
}
.mobile-header .nav-item.active {
  border-left: 5px solid var(--blue600);
}
.mobile-header .nav-item.active a {
  color: var(--blue600);
}

.global-footer {
  background-color: var(--gray100);
  padding: 2.5rem 0;
}
.global-footer .inner {
  display: flex;
  align-items: center;
}
@media screen and (max-width: 928px) {
  .global-footer .inner {
    display: block;
  }
}

.global-footer__logo {
  padding-right: 2rem;
  margin-right: 2rem;
  border-right: 1px solid var(--gray200);
}
.global-footer__logo img {
  width: 250px;
  margin-bottom: 0.5rem;
}
.global-footer__logo p {
  font-size: 0.8rem;
  margin-bottom: 0;
  color: var(--gray300);
}
@media screen and (max-width: 928px) {
  .global-footer__logo {
    border-right: none;
    border-bottom: 1px solid var(--gray200);
    padding: 0 0 1rem 0;
    margin: 0 0 1rem 0;
  }
}

.global-footer__address {
  font-size: 0.8rem;;
  display: flex;
  color: var(--gray400);
  font-style: normal;
}
.global-footer__address div {
  padding-right: 2rem;
}
@media screen and (max-width: 928px) {
  .global-footer__address {
    display: block;
  }
  .global-footer__address div {
    padding: 0;
    margin-bottom: 1rem;
  }
  .global-footer__address div:last-of-type {
    margin-bottom: 0;
  }
}

.top-header {
  padding: 3.5rem 1rem;
}
.top-header.--mobile {
  display: none;
  padding: 0 0 2rem 0;
}
.top-header.--mobile img {
  width: 100%;
}
@media screen and (max-width: 560px) {
  .top-header {
    display: none;
  }
  .top-header.--mobile {
    display: block;
  }
}

.top-header__logo {
  max-width: 100%;
  margin: 0 auto;
}

.top-hero {
  background-image: url(./../images/hero_top-531bb55552e9d0894ef7.jpg);
  background-size: cover;
  background-position: center center;
  color: var(--gray0);
  padding: 4rem 1rem;
}
@media screen and (max-width: 928px) {
  .top-hero {
    padding: 4rem 0;
  }
}

.top-hero__inner {
  width: 600px;
}
@media screen and (max-width: 928px) {
  .top-hero__inner {
    width: 100%;
  }
  .top-hero__inner p {
    font-size: 0.875rem;
  }
}

.top-hero__inner__bottom {
  margin-top: 2rem;
}

.features {
  display: flex;
  flex-wrap: wrap;
  margin: 0 auto;
  padding: 3.5rem 0;
  width: var(--breakpoint-lg);
}
@media screen and (max-width: 928px) {
  .features {
    width: 100%;
  }
}

.features__item {
  transition: background-color 0.3s ease-out;
  width: calc(33.3333% - 2px);
  padding: 1rem 1.5rem 1.5rem 1.5rem;
  text-decoration: none;
  border: 1px solid var(--gray0);
}
.features__item img {
  display: block;
  width: 48px;
  height: 48px;
  margin: 0 auto 8px;
}
.features__item h3 {
  margin-bottom: 1.5rem;
  text-align: center;
  color: var(--blue600);
  letter-spacing: 1px;
}
.features__item p {
  font-size: 0.875rem;
  margin-bottom: 0;
  color: var(--gray600);
}
.features__item:hover {
  background-color: var(--gray100);
}
@media screen and (max-width: 928px) {
  .features__item {
    width: 100%;
    display: flex;
  }
  .features__item img {
    margin: 0;
    margin-right: 1rem;
  }
  .features__item h3 {
    text-align: left;
    margin-bottom: 0.5rem;
  }
}

.pickup {
  background-color: var(--gray100);
  padding: 2rem 0;
}

.pickup__item {
  display: flex;
  margin: 0 auto;
  width: var(--breakpoint-lg);
}
.pickup__item .thumbnail {
  width: 368px;
  border-radius: 0.125rem;
}
.pickup__item .inner {
  display: flex;
  flex-direction: column;
  justify-content: space-between;
  align-items: flex-start;
  padding: 1rem 2rem;
}
.pickup__item .inner h3 {
  color: var(--gray600);
}
@media screen and (max-width: 928px) {
  .pickup__item {
    width: 100%;
    display: block;
  }
  .pickup__item .thumbnail {
    width: auto;
  }
  .pickup__item .inner {
    padding: 1rem 0 0;
  }
  .pickup__item .inner h3 {
    margin-bottom: 1rem;
  }
}

.history {
  padding: 4.5rem 0;
  margin: 0 auto;
  width: var(--breakpoint-lg);
}
@media screen and (max-width: 928px) {
  .history {
    width: 100%;
  }
}

.history__heading {
  color: var(--gray600);
  letter-spacing: 1px;
  margin-bottom: 1.5rem;
}

.history__item {
  font-size: 0.875rem;
  display: flex;
  padding: 1.5rem 0;
  margin-bottom: 0;
  color: var(--gray600);
  border-bottom: 1px solid var(--gray200);
  background-color: rgba(255, 255, 255, 0.8);
}
.history__item date {
  width: 7.5rem;
  color: var(--gray300);
  display: inline-block;
}
.history__item .number {
  width: 3rem;
  color: var(--gray300);
  font-size: 1.25rem;
}
.history__item .desc {
  flex: 1;
  line-height: 1.5rem;
}
.history__item:last-of-type {
  border-bottom: none;
}
@media screen and (max-width: 928px) {
  .history__item {
    display: block;
  }
  .history__item date {
    margin-bottom: 0.5rem;
  }
}

.detail-hero {
  background-image: url(./../images/hero_about-deb80eaf643a3287f9b4.jpg);
  background-size: cover;
  background-position: center center;
  padding: 4rem 1rem;
}
@media screen and (max-width: 928px) {
  .detail-hero {
    padding: 4rem 0;
  }
}
.detail-hero.--about {
  background-image: url(./../images/hero_about-deb80eaf643a3287f9b4.jpg);
}
.detail-hero.--researches {
  background-image: url(./../images/hero_researches-d7c3eaa0b5a102f882ef.jpg);
}
.detail-hero.--projects {
  background-image: url(./../images/hero_projects-16896beed0c09268c031.jpg);
}
.detail-hero.--achievements {
  background-image: url(./../images/hero_achievements-fe0e02c377f2d90a0fce.jpg);
}
.detail-hero.--members {
  background-image: url(./../images/hero_members-065157b1be8905337c7d.jpg);
}

.detail-hero__inner img {
  height: 80px;
}

.detail-inner {
  background-image: url(./../images/bg_01-1fa4ea6ccadfd02af72f.svg);
  background-repeat: repeat-y;
  background-position: top right;
}
@media screen and (max-width: 928px) {
  .detail-inner {
    background-size: 300px;
    background-position: 240px top;
  }
}
.detail-inner.--no-bg {
  background-image: none;
}

.detail-content {
  padding: 5rem 1rem;
  width: 720px;
  color: var(--gray600);
  line-height: 2rem;
}
.detail-content h3 {
  font-size: 1.5rem;
  margin-top: 4rem;
  margin-bottom: 2rem;
}
.detail-content p {
  margin-bottom: 2rem;
}
.detail-content .history__item p {
  margin-bottom: 0;
}
@media screen and (max-width: 928px) {
  .detail-content {
    padding: 3rem 0;
    width: 100%;
    line-height: 1.725rem;
  }
}

/* 既存のスタイル */
.detail-content.--wide {
  padding-top: 0;
  margin-bottom: 0;
}

/* 追加のスタイル */
.detail-content.--wide + .detail-content.--wide {
  margin-top: -20px; /* 2つの.detail-content --wide間の上部マージンを減らす */
}

/* .detail-content --wideの最初の子要素の上部マージンを0に設定 */
.detail-content.--wide > :first-child {
  margin-top: 0;
}

.detail-title {
  font-size: 2rem;
  line-height: 3.5rem;
  font-family: serif;
  color: var(--blue600);
  margin: 3rem 0;
}

.introduction h2 {
  font-family: serif;
  font-size: 1.75rem;
  text-align: center;
  padding: 10px 7px 7px 0.5em;
  line-height: 1.2173913043;
  margin-top: 2.4347826087em;
  margin-bottom: 1.2173913043em;
  color: #FFFFFF;
  background: -moz-linear-gradient(left, rgba(255,255,255,0.1), rgb(18, 147, 252) 10%, rgba(22 106 181) 90%, rgba(255,255,255,0.1));
  background: -webkit-linear-gradient(left, rgba(255,255,255,0.), rgb(43 153 246) 10%, rgba(22 106 181) 90%, rgba(255,255,255,0.1));
  background: linear-gradient(to right, rgba(255,255,255,0.1), rgb(43 153 246) 10%, rgb(10, 102, 183) 90%, rgba(255,255,255,0.1));
}

.introduction h3 {
  font-family: serif;
  font-weight: 700;
  font-size: 24px;
  border-left: 7px solid #0e5394;
  line-height: 1.2173913043;
  margin-top: 2.4347826087em;
  margin-bottom: 1.2173913043em;
  color: #0e5394;
  padding: 0.3em;
  padding-left: 0.3em;
  background-color: transparent;
  text-decoration: none;
}

.introduction h6 {
  font-family: serif;
  font-size: 16px;
  color: #186eba;
}


.introduction a {
  font-family: serif;
  color: #166bb7;
  text-decoration: underline dotted;
}

p.link_yellow:after {
  font-size: 16px;
  font-size: 1rem;
  padding-left: 0.2em;
  content: "\f152";
  font-family: "Font Awesome 5 Free";
  color: #ffb258;
}

.introduction li {
  font-family: serif;
  color: #166bb7;
}

.health_research {
  padding-top: 50px;
  padding-bottom: 50px;
  text-align: center;
}

@media screen and (max-width: 928px) {
  .detail-title {
    font-size: 1.5rem;
    line-height: 2.5rem;
  }

  .introduction h2 {
    font-size: 1.2rem;
    text-align: center;
    padding: 10px 7px 7px 0.5em;
    line-height: 1.2173913043;
    margin-top: 2.4347826087em;
    margin-bottom: 1.2173913043em;
    color: #FFFFFF;
    background: -moz-linear-gradient(left, rgba(255,255,255,0.1), rgb(43 153 246) 10%, rgba(22 106 181) 90%, rgba(255,255,255,0.1));
    background: -webkit-linear-gradient(left, rgba(255,255,255,0.), rgb(43 153 246) 10%, rgba(22 106 181) 90%, rgba(255,255,255,0.1));
    background: linear-gradient(to right, rgba(255,255,255,0.1), rgb(43 153 246) 10%, rgba(22 106 181) 90%, rgba(255,255,255,0.1));
  }
  
  .introduction h3 {
    font-weight: 700;
    font-size: 18px;
    border-left: 7px solid #166bb7;
    line-height: 1.2173913043;
    margin-top: 2.4347826087em;
    margin-bottom: 1.2173913043em;
    color: #166bb7;
    padding: 0.3em;
    padding-left: 0.3em;
    background-color: transparent;
    text-decoration: none;
  }
}
.detail-title .badge {
  font-size: 1.1rem;
  font-family: sans-serif;
  font-weight: normal;
  margin-bottom: 0;
  line-height: 1.5rem;
}
.detail-title.--black {
  color: var(--gray900);
}

.detail-full-img {
  width: 100%;
  margin-bottom: 2rem;
}

.profile {
  display: flex;
  align-items: flex-start;
}
@media screen and (max-width: 560px) {
  .profile {
    flex-wrap: wrap;
  }
}

.profile__content {
  margin-left: 2rem;
}
@media screen and (max-width: 560px) {
  .profile__content {
    margin-left: 0;
  }
}

.profile__photo {
  width: 167px;
  border-radius: 0.25rem;
}
.profile__photo.--sm {
  width: 140px;
}
@media screen and (max-width: 560px) {
  .profile__photo {
    margin-bottom: 1rem;
  }
}

.banner {
  display: flex;
  align-items: center;
  border: 1px solid var(--gray200);
  background-color: var(--gray0);
  border-radius: 0.25rem;
  padding: 0.5rem;
  text-decoration: none;
  color: var(--gray900);
}
.banner img {
  width: 140px;
  height: 140px;
  margin: 0;
  margin-right: 1.5rem;
  border-radius: 0.15rem;
}
.banner:hover {
  border-color: var(--blue600);
}
@media screen and (max-width: 560px) {
  .banner img {
    width: 80px;
    height: 80px;
    margin-right: 0.5rem;
  }
}

.banner__title {
  font-size: 1.25rem;
  margin-bottom: 0.5rem;
}
@media screen and (max-width: 560px) {
  .banner__title {
    font-size: 1rem;
    margin-bottom: 0;
  }
}

.banner__description {
  font-size: 0.875rem;
  line-height: 1.5rem;
}
@media screen and (max-width: 560px) {
  .banner__description {
    display: none;
  }
}

html {
  font-size: 16px;
  font-family: sans-serif;
  color: var(--gray900);
}

a {
  color: var(--blue600);
}

h1 {
  font-size: 2rem;
  line-height: 3.5rem;
  font-weight: 500;
  margin-bottom: 1rem;
}
@media screen and (max-width: 928px) {
  h1 {
    font-size: 1.5rem;
    line-height: 2rem;
  }
}

h3 {
  font-size: 1.25rem;
  font-weight: 500;
  line-height: 2rem;
  margin-bottom: 1rem;
}

hr {
  border: 0;
  border-bottom: 1px solid var(--gray300);
  padding: 0;
  margin: 1rem 0;
}

.container {
  width: 1088px;
  max-width: 100%;
  margin: 0 auto;
}
@media screen and (max-width: 928px) {
  .container {
    padding-left: 1.5rem;
    padding-right: 1.5rem;
  }
}

.badge {
  font-size: 0.85rem;
  color: var(--gray600);
  font-weight: 600;
  margin-bottom: 0.5rem;
}

.btn-round {
  transition: background-color, border-color, color 0.3s ease-out;
  text-decoration: none;
  display: inline-block;
  color: var(--gray900);
  background-color: var(--gray0);
  border: 1px solid var(--gray200);
}
.btn-round:hover {
  color: var(--gray0);
  background-color: var(--gray600);
  border-color: var(--gray600);
}
.btn-round.--md {
  font-size: 1rem;
  line-height: 2rem;
  padding: calc(0.5rem - 1px) 2rem;
  border-radius: 2rem;
}
.btn-round.--primary {
  color: var(--gray0);
  background-color: var(--blue600);
  border-color: var(--blue600);
}
.btn-round.--primary:hover {
  color: var(--blue600);
  background-color: var(--gray0);
  border-color: var(--blue600);
}

.map-responsive {
  overflow: hidden;
  padding-bottom: 56.25%;
  position: relative;
  height: 0;
}

.map-responsive iframe {
  left: 0;
  top: 0;
  height: 100%;
  width: 100%;
  position: absolute;
}

.bordered {
  text-decoration: underline;
}