FAD-dependent, mitochondrial glycerol-3-phosphate dehydrogenase (GPD)

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FAD-dependent, mitochondrial glycerol-3-phosphate dehydrogenase (GPD) (EC 1.1.99.5) is located in the outer surface of the inner mitochondrial membrane. The mammalian enzyme is homologous to the yeast and eubacterial FAD-glycerol-3-phosphate dehydrogenases and has two EF-hands at its C-terminus, unlike its yeast and bacterial homologs [46].