Table 5

         
pp-tab5        
table5
Name Ligand Effect/comments References
1 Calmodulin 110(review)
Myosin light chain kinase (+) 1418, 1846, 5009
NAD kinase (+) 5438, 819
Glycogen phosphorylase kinase (+) 1771
Calmodulin-dependent protein kinase (+) 4229
Calcineurin (protein phosphatase) (+) 5235
Cyclic nucleotide phosphodiesterase (+) 1705a, 2703a
Adenylate cyclase (Bordetella) (+) 2804, 5382, 33
Guanylate cyclase (+) 6525
Nitric oxide synthase (+) 1612, 1221a
Ca2+ -Mg2+ ATPase (110kDa) (?)
Dynein ATPase (?) 5366
Phosphofructokinase (?) /four CaM / dimer 5390
Glycogen synthase kinase (?) /affects rate of phosphorylation 5868
Glycogen phosphorylase (?) /gel binding 6026
Tetrahumena ciliary membrane (?) /guanylate cyclase? 344
Microtubule (?) /tau or MAP2 in kinetochore? 5991
Insulin receptor (?) /Kinase for CaM part of receptor 724
K+ channel (?) /source of calcium sensitivity? 3700
Flagellar membrane (?) Ca-ATPase? effect mobility? 1564
Caldesmon (?) /in vitro binding 5953
Cytosynalin (?) gel binding, thin filament stain 5970
Troponin I (-) /substitute for troponin C 1902
Inositol triphosphate kinase (?) /Ca-CaM stimulation 1473
CaM-BP 103/97 (?) /gel binding, protein kinase C substrate
Endoplasmic retic 115 kDa (?) /gel binding 5477
P-57 (neuromodulin) (?) /neurospecific? 6036
Fodrin (spectrin) (?) /affinity chromatography 5523
Synaptic vesicle (?) /cholinergic, Ca independent 2506
55 kDa (Electrophorus) (?) /partially pure 5610
MAP2 (?) 5654
Tau (?) 5965
Synapsin (?) 5836
Tubulin (?) 3623, 5671
Calponin (?) nonspecific? 7166
HSP90 Inhibition of actin binding 7121
Melittin and mastoparan (-) 5733, 5443
ACTH (-) 6677
Beta- endorphin (-) 5514, 6677
Substance P (-) 6677
Glucagon (-) 6677
W-7
Phenothiazine
2 Troponin C Troponin I 230
Calponin 7166
3 Essential light chain Myosin heavy chain 274, 3281
4 Regulatory light chain Myosin heavy chain 274, 3281
5 Troponin C, nonvertebrate Troponin I 492, 6293
7 Squidulin Chlorpromazine and fluphenazine 429
Melitin 429
Axoplasmic myosin PNAS 93:6064-6068 (96)
12 P22 Microtuble Mol. Biol. Cell 10:3473-3488 (99)
Calcineurin JBC 274:36125-31 (99)
Na+-H+-exchanger PNAS 93:12631 (96)
13 Visinin Guanylate cyclase GCAP TINS 19:547-554 (1996)
Rhodopsin kinase ? Recoverin TINS 19:547-554 (1996)
15 DRE antagonist modulator downstream regulatory element (DRE, DNA) Nature 398:80 (99)
20 Calpain Phospholipid 3501
Casein [Substrate]
Phosphorylase b kinase [Substrate]
Protein kinase C [Substrate]
cAMP-dependent protein kinase [Substrate]
Pyruvate kinase [Substrate]
Glycogen synthase [Substrate]
Tyrosine hydroxylase [Substrate]
Spectrin [Substrate]
Fodrin [Substrate]
Estrgen receptor [Substrate]
Glucocorticoid receptor [Substrate]
EGF receptor [Substrate]
Muscle fiber proteins [Substrate]
Ezrin [Substrates] 7173
Calponin [Substrate] 4716
21 Sorcin Annexin VII Sorcin JBC 272:22182 (97)
Ryanodyne receptor Sorcin JBC 272:25333 (97)
    Presenilin 2 Sorcin JBC 275:14440-14445 (2000)
22 S100, intestinal calcium-binding protein Fructose-1,6-bisphosphate aldolase S100A1 & S100B 6100
Glial fibrillary acidic protein (S100) S100A1 & S100B 5360
Aldolase S100A1 & S100B Biometals 11:383-397 (1998)
Tublin S100A1 & S100B Biometals 11:383-397 (1998)
Caldesmon S100A1 & S100B Biometals 11:383-397 (1998)
bHLH transcription factors S100A1 & S100B Biometals 11:383-397 (1998)
Glycogen phosphorylase S100A1 Biometals 11:383-397 (1998)
Adenyl cyclase S100A1 Biometals 11:383-397 (1998)
Twitchin kinase S100A1 Biometals 11:383-397 (1998)
CapZ S100A1 & S100B Biometals 11:383-397 (1998)
F-actin S100A1 Biometals 11:383-397 (1998)
Ryanodyne receptor S100A1 Biometals 11:383-397 (1998)
Tropomyosin S100A2 Biometals 11:383-397 (1998)
Chemotactic receptor S100A2 Biometals 11:383-397 (1998)
Non-muscle tropomyosin S100A4 Biometals 11:383-397 (1998)
p53 S100A4 Biometals 11:383-397 (1998)
Non-muscle myosin S100A4 Biometals 11:383-397 (1998)
MAP S100A4 Biometals 11:383-397 (1998)
p37 S100A4 Biometals 11:383-397 (1998)
Annexin II S100A6 Biometals 11:383-397 (1998)
Annexin VI S100A6 Biometals 11:383-397 (1998)
Annexin XI S100A6 Biometals 11:383-397 (1998)
Glyceraldehyde-3-phosphate dehydrogenase S100A6 Biometals 11:383-397 (1998)
Caldesmon S100A6 Biometals 11:383-397 (1998)
Caltropin S100A6 Biometals 11:383-397 (1998)
Vimentin S100A8 & S100A9 Biometals 11:383-397 (1998)
85-kDa phospholipae A2 S100A10 Biometals 11:383-397 (1998)
Annexin I S100A11 Biometals 11:383-397 (1998)
FGF-1/p40Syn-1/A13 complex S100A13 Biometals 11:383-397 (1998)
GAP43 S100B Biometals 11:383-397 (1998)
Calponin S100B Biometals 11:383-397 (1998)
Tau protein S100B Biometals 11:383-397 (1998)
Neurocalcin S100B Biometals 11:383-397 (1998)
p53 S100B Biometals 11:383-397 (1998)
Nuclear Ser/Thr protein kinase S100B Biometals 11:383-397 (1998)
p36 (calpactin light chain) By p10 dimer to form calpactin 6218
Calponin (11-kDa SMCaBP = calcyclin) 7166
Calponin S100B (S100b) 7166
Caldesmon (11-kDa SMCaBP = calcyclin) 3218
25 Diacylglycerol kinase Diacylglycerol [Substrate] 6421
ATP [Substrate]
28 Alfa-Actinin Actin 2991
29 Alpha-spectrin Actin
43 Calcium-dependent protein kinase W-7 4181, 5279
2-Trifluoromethyl-10H-10-(3' aminopropyl)
Phenothiazine
Lysophosphatidylcholine
Phosphatidylinositol
ATP [Substrate]
Histone III-S [Substrate]
Myosin light chains, (gizzaard) [Substrate]
49 Aequorin and luciferin-binding protein Luciferin 2961, 6766a, 6625a
Celentrazine-2-hydroperoxide (Aequorin)
53 Calcium vector protein Melittin 5170
Endogenous 36 kDa protein
59 Fimbrin Actin
update: Oct. 16, 2000