{"id":50,"date":"2017-04-12T16:34:00","date_gmt":"2017-04-12T07:34:00","guid":{"rendered":"http:\/\/www-user.yokohama-cu.ac.jp\/~gastro\/?page_id=50"},"modified":"2025-04-01T21:30:01","modified_gmt":"2025-04-01T12:30:01","slug":"%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6%e3%82%84%e6%b2%bb%e9%a8%93%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"page","link":"https:\/\/www-user.yokohama-cu.ac.jp\/~gastro\/?page_id=50","title":{"rendered":"\u81e8\u5e8a\u7814\u7a76\u3084\u6cbb\u9a13\u306b\u3064\u3044\u3066"},"content":{"rendered":"

\u809d\u81d3\u30b0\u30eb\u30fc\u30d7<\/h4>\n

C\u578b\u809d\u708e<\/h5>\n
    \n
  1. Direct acting antivirals(DAAs)\u4f75\u7528\u7642\u6cd5\u306e\u524d\u5411\u304d\u89b3\u5bdf\u7814\u7a76\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3001\u591a\u65bd\u8a2d\u5171\u540c\u8a66\u9a13\uff09
    \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7 D1409019<\/li>\n
  2. Effect of Sofosbuvir or Ledipasvir\/Sofosbuvir Therapy on Liver Fibrosis in Japanese Patients with Hepatitis C Virus Infection\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3001\u591a\u65bd\u8a2d\u5171\u540c\u8a66\u9a13\uff09
    \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7 D1601014<\/li>\n<\/ol>\n
    \u8d85\u97f3\u6ce2\u3001\u809d\u764c<\/h5>\n
      \n
    1. \u7814\u7a76\u540d\uff1a\u591a\u8840\u809d\u7d30\u80de\u764c\u306e\u9670\u5f71\u6b20\u640d\u8a55\u4fa1\u306b\u304a\u3051\u308b\u30da\u30eb\u30d5\u30eb\u30d6\u30bf\u30f3\uff08\u30bd\u30ca\u30be\u30a4\u30c9\u00ae\uff09\u306e\u4f4e\u97f3\u5727\u9020\u5f71\u30e2\u30fc\u30c9\u3068\u9ad8\u97f3\u5727\u9020\u5f71\u30e2\u30fc\u30c9\u306e\u6bd4\u8f03\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7\u3000D1601002<\/li>\n
    2. \u300cB-mode\u3067\u691c\u51fa\u56f0\u96e3\u306a\u809d\u7d30\u80de\u764c\u306b\u5bfe\u3059\u308b\u878d\u5408\u753b\u50cf\u306b\u3088\u308b\u9020\u5f71\u8d85\u97f3\u6ce2\u30ac\u30a4\u30c9\u4e0bRFA\u306e\u6cbb\u7642\u52b9\u679c\u5224\u5b9a\u306e\u6709\u7528\u6027\u300d\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7 B170100022<\/a><\/li>\n
    3. 3D\u30b9\u30e9\u30a4\u30b5\u30fc\u3092\u7528\u3044\u305fHIFU(\u96c6\u675f\u8d85\u97f3\u6ce2\uff09\u6cbb\u7642\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7 D1603001<\/li>\n
    4. 5-\u30a2\u30df\u30ce\u30ec\u30d6\u30ea\u30f3\u9178(5-ALA)\u306eHIFU\u306e\u52b9\u679c\u5897\u5f37\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7D1510017<\/li>\n
    5. Template matching\u3092\u7528\u3044\u305f\u96c6\u675f\u8d85\u97f3\u6ce2(HIFU)\u306b\u304a\u3051\u308b\u547c\u5438\u30c8\u30e9\u30c3\u30ad\u30f3\u30b0\u306e\u5fdc\u7528\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f714008<\/li>\n
    6. 3D\u30b9\u30e9\u30a4\u30b5\u30fc\u3092\u7528\u3044\u305f\u30e9\u30b8\u30aa\u6ce2\u71b1\u51dd\u56fa\u7642\u6cd5(RFA)\u306e\u7a7f\u523a\u30a2\u30b7\u30b9\u30c8\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f713003<\/li>\n
    7. Template matching \u3092\u7528\u3044\u305f\u30e9\u30b8\u30aa\u6ce2\u71b1\u51dd\u56fa\u7642\u6cd5(RFA),\u9020\u5f71\u8d85\u97f3\u6ce2\u306b\u304a\u3051\u308b\u547c\u5438\u30c8\u30e9\u30c3\u30ad\u30f3\u30b0\u306e\u5fdc\u7528\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7D1409030<\/li>\n
    8. \u809d\u764c\u306b\u304a\u3051\u308b\u8840\u4e2dmicroRNA\u306e\u7814\u7a76\u3000\uff08\u9644\u5c5e\u5e02\u6c11\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc\uff09
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7       B170100021<\/a><\/li>\n
    9. \u809d\u7d30\u80de\u764c\u306b\u5bfe\u3059\u308b\u5c40\u6240\u6cbb\u7642(\u30e9\u30b8\u30aa\u6ce2\u7a7f\u523a\u7642\u6cd5\u3001\u4f53\u5e79\u90e8\u5b9a\u4f4d\u653e\u5c04\u7dda\u6cbb\u7642)\u306e\u5c40\u6240\u5236\u5fa1\u7387\u3068\u5b89\u5168\u6027\u3092\u6bd4\u8f03\u3059\u308b\u5f8c\u65b9\u8996\u7684\u7814\u7a76
      \n\u502b\u7406\u59d4\u54e1\u4f1a\u627f\u8a8d\u756a\u53f7       B170200026<\/a><\/li>\n<\/ol>\n

      \u80c6\u81b5\u30b0\u30eb\u30fc\u30d7<\/h4>\n

      EGFR\u5897\u5e45\u3092\u4f34\u3046\u9032\u884c\u80c6\u9053\u764c\u306b\u5bfe\u3059\u308b\u30cd\u30b7\u30c4\u30e0\u30de\u30d6\uff0c\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3\u4f75\u7528\u7642\u6cd5\u306e\u6709\u52b9\u6027\u3092\u691c\u8a0e\u3059\u308b\u7b2c\u2161\u76f8\u8a66\u9a13<\/span><\/span><\/a><\/p>\n

      PI3K\u7d4c\u8def\u4ea2\u9032\u578b\u80c6\u9053\u764c\u306b\u5bfe\u3059\u308b\u30ab\u30d4\u30d0\u30bb\u30eb\u30c1\u30d6\u5358\u5264\u7642\u6cd5\u306e\u7b2c\u2161\u76f8\u8a66\u9a13<\/a><\/p>\n

      \u672c\u90a6\u306b\u304a\u3051\u308b\u304c\u3093\u30b2\u30ce\u30e0\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u691c\u67fb\u3092\u5b9f\u65bd\u3055\u308c\u305f\u6d88\u5316\u5668\u764c\u306e\u5b9f\u614b\u8abf\u67fb<\/span><\/span><\/a><\/p>\n

      \u8d85\u97f3\u6ce2\u5185\u8996\u93e1\u4e0b\u7d44\u7e54\u63a1\u53d6\u3067NCC\u30aa\u30f3\u30b3\u30d1\u30cd\u30eb\u691c\u67fb\u306b\u63d0\u51fa\u3057\u305f\u81b5\u764c\u75c7\u4f8b\u306b\u304a\u3051\u308bDNA\u54c1\u8cea\u306e\u691c\u8a0e<\/span><\/span><\/a><\/p>\n

      \u6839\u6cbb\u5207\u9664\u5f8c\u80c6\u9053\u764c\u306b\u5bfe\u3059\u308b\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u306eS-1\u7642\u6cd5\u306e\u7b2cIII\u76f8\u8a66\u9a13\uff08JCOG1202\uff09<\/a><\/p>\n

      \u5316\u5b66\u7642\u6cd5\u672a\u6cbb\u7642\u85ac\u306e\u9060\u9694\u8ee2\u79fb\u3092\u6709\u3059\u308b\u81b5\u764c\u306b\u5bfe\u3059\u308b\u3000L-OHP+CPT-1165FU\/I-LV\u4f75\u7528\u7642\u6cd5 modified regimen(mFFX)\u3000\u306e\u7b2c\u2161\u76f8\u8a66\u9a13<\/p>\n

      \u9032\u884c\u80c6\u9053\u764c\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3+\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u4f75\u7528\u7642\u6cd5\uff08GC\u7642\u6cd5\uff09\u3068\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3+S-1\u4f75\u7528\u7642\u6cd5\uff08GS\u7642\u6cd5\uff09\u306e\u7b2cIII\u76f8\u6bd4\u8f03\u8a66\u9a13\uff08JCOG1113)\u306e\u9644\u968f\u7814\u7a76<\/a><\/p>\n

      \u826f\u60aa\u6027\u80c6\u7ba1\u72ed\u7a84\u306b\u5bfe\u3059\u308b\u80c6\u7ba1\u5185\u57cb\u3081\u8fbc\u307f\u578b\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30b9\u30c6\u30f3\u30c8\u306e\u6709\u7528\u6027\u3068\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306e\u591a\u65bd\u8a2d\u5171\u540c\u524d\u5411\u304d\u7814\u7a76<\/p>\n

      \u6d88\u5316\u7ba1\u30fb\u809d\u80c6\u81b5\u539f\u767a\u306e\u5207\u9664\u4e0d\u80fd\u30fb\u518d\u767a\u795e\u7d4c\u5185\u5206\u6ccc\u764c\uff08NEC\uff09\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30a8\u30c8\u30dd\u30b7\u30c9\uff0f\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\uff08EP\uff09\u7642\u6cd5\u3068\u30a4\u30ea\u30ce\u30c6\u30ab\u30f3\uff0f\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\uff08IP\uff09\u7642\u6cd5\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13(<\/a>JCOG1213)<\/a><\/p>\n

      \u81b5\u764c\u30fb\u4e73\u764c\u30fb\u5375\u5de3\u764c\u30fb\u524d\u7acb\u817a\u764c\u3044\u305a\u308c\u304b\u306e\u5bb6\u65cf\u6b74\u3092\u6709\u3059\u308b\u3001\u307e\u305f\u306f\u3001\u4e73\u764c\u30fb\u5375\u5de3\u764c\u30fb\u524d\u7acb\u817a\u764c\u3044\u305a\u308c\u304b\u306e\u65e2\u5f80\u6b74\u3092\u6709\u3059\u308b\u3001\u9060\u9694\u8ee2\u79fb\u3092\u4f34\u3046\u81b5\u764c\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3\/\u30aa\u30ad\u30b5\u30ea\u30d7\u30e9\u30c1\u30f3\u7642\u6cd5\uff08GEMOX\u7642\u6cd5\uff09\u306e\u591a\u65bd\u8a2d\u5171\u540c\u7b2cII\u76f8\u8a66\u9a13<\/p>\n

      \u5c40\u6240\u9032\u884c\u81b5\u764c\u3092\u5bfe\u8c61\u3068\u3057\u305fmodified FOLFIRINOX\u7642\u6cd5\u3068\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3+\u30ca\u30d6\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u4f75\u7528\u7642\u6cd5\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u7b2c\u2161\u76f8\u8a66\u9a13\uff08JCOG1407\uff09<\/a><\/p>\n

      76 \u6b73\u4ee5\u4e0a\u306e\u5207\u9664\u975e\u9069\u5fdc\u81b5\u764c\u60a3\u8005\u306b\u5bfe\u3059\u308b\u975e\u624b\u8853\u7642\u6cd5\u306e\u524d\u5411\u304d\u89b3\u5bdf\u7814\u7a76<\/p>\n

      \u5207\u9664\u4e0d\u80fd\u30fb\u518d\u767a\u81b5\u817a\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u5bfe\u3059\u308b\u5316\u5b66\u7642\u6cd5\u306e\u6cbb\u7642\u6210\u7e3e\u306b\u95a2\u3059\u308b\u591a\u65bd\u8a2d\u5171\u540c\u5f8c\u308d\u5411\u304d\u89b3\u5bdf\u7814\u7a76<\/p>\n

      \u80c6\u9053\u764c\u306e\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u306b\u304a\u3051\u308b\u85ac\u5264\u611f\u53d7\u6027\u4e88\u6e2c\u56e0\u5b50\u306b\u95a2\u3059\u308b\u63a2\u7d22\u7684\u7814\u7a76(JCOG1202A1)<\/a><\/p>\n

      \u5341\u4e8c\u6307\u8178\u72ed\u7a84\u3092\u6709\u3059\u308b\u5207\u9664\u4e0d\u80fd\u81b5\u817a\u764c\u3092\u5bfe\u8c61\u3068\u3057\u305f\u521d\u56de\u5316\u5b66\u7642\u6cd5\u5c0e\u5165\u524d\u306e\u72ed\u7a84\u89e3\u9664\u65b9\u6cd5\u306b\u95a2\u3059\u308b\u591a\u65bd\u8a2d\u5171\u540c\u5f8c\u308d\u5411\u304d\u89b3\u5bdf\u7814\u7a76<\/p>\n

      \u80c6\u81b5\u9818\u57df\u306e\u816b\u760d\u6027\u75be\u60a3\u306b\u304a\u3051\u308b\u8840<\/span>\u4e2d<\/span>\u904a\u96e2<\/span>\u907a\u4f1d<\/span>\u5b50\u306e\u89e3\u6790<\/p>\n

      \u6d88\u5316\u7ba1\u30b0\u30eb\u30fc\u30d7<\/h4>\n