Troponin, nonvertebrate (TPNV)

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Troponin, nonvertebrate (TPNV) is found in various nonvertebrates; for example lobster has three isoforms [11]. It is a close homolog of TNC; however, its mode of function remains unknown and it clusters in a subfamily distinct from TNC. The interdomain linkers of CAM, TNC, ELC, and RLC are bent when those proteins are bound to a target. In contrast, the 2,3 linker of TPNV is predicted to be strongly helical and hence not to bend.