Squidulin (SQUD)

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Squidulin (SQUD) is identical to vertebrate CAM in 101 of 149 positions; however, its Lys115 is not methylated; Lys115 of CAM is trimethylated. Further, it has a Pro at the second residue of the 2-3 linker, which is helical in CAM when it is not bound to a target. SQUD co-purifies with the 235 kDa myosin of squid axoplasm and is inferred to function as a myosin light chain [13].