LAV1 (LAV) cDNA encodes a 355 residue protein. Different isoforms
are expressed in amoebae and in plasmodia of Physarum polycephalum
. Domains 2 and 4 of LAV most closely resemble one another.
Although LAV appears not to be congruent with any other EF- hand
protein, its interdomains 1,2 and 3,4 resemble 1,2 and 3,4 of CTER.
Linker 2,3 consists of a sole Leu. This places severe constraints on
the spatial relationship between the lobe 1,2 and the C-terminal lobe.
The function of LAV is not known and no homolog has been identified for
the ~200 residues at its N-terminus.