Trichohyalin and profilaggrin (HYFL)
entry list
alignment
Trichohyalin and profilaggrin (HYFL) have two EF-hands at their
N-termini, both of which are congruent with S100 and with ICBP.
However, trichohyalin contains seven tandemly repeated domains
homologous to involucrin at its C-terminus [37]. Profilaggrin has ten
to twelve filaggrin domains at its C-terminus [38]. Both associate
with keratin intermediate filaments.