Fimbrin (FIMB)

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Fimbrin (FIMB) is an actin filament bundling protein from chick. It has two EF-hands at its N-terminus and four, 125 residue actin binding domains, homologous to those of _-actinin, at its C-terminus [81]. The human homologs are I, L, and T-plastin whose genes are on chromosomes 3, 13, and X [82]. Eventhough FIMB bears some similarities to ACTN, their pairs of EF-hands are not closely related.