Caltractin (CDC)

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Caltractin (CDC) was initially cloned from the unicellular green alga, Chlamydomonas. It is a structural component of the basal body complex, the major microtubule organizing center in Chlamydomonas and the functional homolog of the centrosome in the animal cell. The CDC31 gene product, a yeast homolog of caltractin, interacts with the KAR1 product. KAR1 encodes an essential component of the yeast spindle pole body that is required for karyogamy and duplication of the spindle pole body [14].