Allograft inflammatory factor-1 (AIF1)

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Allograft inflammatory factor-1 (AIF1) is "a cytokine inducible, tissue-specific transcript transiently expressed in response to vascular trauma." [47]. It has 143 residues with two EF- hands. Homologs of the first fifty residues have not been identified. The first domains of AIF1 and of GPD are most similar. The arrangement of possible calcium binding ligands (S- G-G---S--D) of the second EF-hand is unusual.