_-Actinin (ACTN)
entry list
alignment
_-Actinin (ACTN) cross links actin filaments non-covalently. It is
a homodimer whose subunits assemble in an antiparallel fashion to form
a rod like structure [43]. The difference between nonmuscle and muscle
forms is that the cross linking activity of the former is completely
inhibited by _M calcium, while the activity of the muscle form is not
calcium sensitive. Both forms have two EF-hand domains at their
C-terminii.