| table2.html | ||||||
| ID | Name | Parameter | Value | Refs | ||
| 1 | CAM | Calmodulin | stokes radius (A) | 20.9 (+Ca) | 107 | |
| 21.4 (+EDTA) | 107 | |||||
| S-value (S) | 1.87 (+Ca) | 107 | ||||
| 1.83 (-Ca) | 107 | |||||
| Moleular Weight | 16680 (mammal) | 107 | ||||
| pI | 3.9-4.3 | 107 | ||||
| A276 (1%, 1cm) | 1.8 (+Ca) | 107 | ||||
| 2.0 (-Ca) | 107 | |||||
| Kd (uM) [Ca2+] | Calmodulin | 107 | ||||
| 1) 1.0 (1 site), 0.012 (2 site) | ||||||
| 2) 3.5 (3 sites), 18 (1 site) | ||||||
| 3) 1.1 (2 sites), 860 (2 sites) | ||||||
| 4) 0.2 (3 sites), 1.0 (1 site) | ||||||
| 5) 3.0 (3 sites) | ||||||
| 6) 2.4 (4 sites) | ||||||
| 7) 3.3 (1 site), 1.0 (1 site), 8.6 (1 site), 20 (1 site) | ||||||
| 8) 5.0 (1 site), 4.0 (1 site), 25 (1 site), 40 (1 site) | ||||||
| Calmodulin-like protein | 6866 | |||||
| (0mM Mg2+) | ||||||
| K1=62 | ||||||
| K2=20 | ||||||
| K3=140 | ||||||
| K4=600 | ||||||
| (10mM Mg2+) | ||||||
| K1=66 | ||||||
| K2=110 | ||||||
| K3=290 | ||||||
| K4=1000 | ||||||
| 2 | TNC | Troponin C | Molecular Weight | 17965 (Sus, skeletal) | ||
| 18299 (Rana, skeletal) | ||||||
| 17794 (Halocynthia) | ||||||
| 18459 (Bos, cardiac) | ||||||
| A280 (1%, 1cm) | 1.93 (Oryctolagus, skeletal) | 5203 | ||||
| Kd (uM) [Ca2+] | 0.1 (sites 1 and 2), 10 (sites 3 and 4) | 414 | ||||
| Kd (uM) [Mg2+] | 1000(sites 1 and 2) | |||||
| 3 | ELC | Essential Light Chain | Molecular Weight | 20700 (Oryctolagus) | ||
| 16500 (Oryctolagus) | ||||||
| 16131 (Physarum) | ||||||
| 17616 (Aquipecten) | ||||||
| A280 (1%, 1cm) | 2.0 (Oryctolagus, alkaline) | 2877, 274 | ||||
| Kd (uM) [Ca2+] | 1 (U.V. and fluorescence change, Physarum) | 2970 | ||||
| 500 (CD change, Aquipectin) | ||||||
| 1 (gel filtration, Aquipectin) | ||||||
| Kd (uM) [Mg2+] | 1000 (CD change, Aquipectin) | 274 | ||||
| 4 | RLC | Regulatory Light Chain | Molecular Weight | 19692 (Gallus, gizzard) | ||
| 17521 (Chlamys) | ||||||
| 17507 (Patinopecten) | ||||||
| A280 (1%, 1cm) | 5.5 (Oryctolagus, skeletal DTNB) | 484 | ||||
| Kd (uM) [Ca2+] | 5.6 & 102 (n=2, Oryctolagus skeletal) | 487 | ||||
| 8 (CD change, Orystolagus) | ||||||
| 200 (CD change, Aquipecten) | ||||||
| Kd (uM) [Mg2+] | 800 (CD change, Aquipecten) | 274 | ||||
| 5 | TPNV | Troponin C, Nonvertebrate | Molecular Weight | 17157 (Astacus, alpha) | ||
| 16974 (Homarus, gamma) | ||||||
| 17984 (Balanus, 1) | ||||||
| 16838 (Balanus, 2) | ||||||
| Kd (uM) [Ca2+] | 1.0 and 80 (n=2, Astacus, alpha) | 6293, 6288 | ||||
| 70 (n=2,Astacus, gamma) | ||||||
| 13 (n=2, Balanus) | ||||||
| 6 | CLAT | CAM-like leaf protein (Arabidopsis) | Molecular weight | 21.7 kDa | Plant Mol Biol 1993 May;22(2):207-14 (UI: 93283626) | |
| 7 | SQUD | Squidulin | Molecular Weight | 16894 | ||
| Kd (uM) [Ca2+] | 1-2 (by fluphenazine binding) | 429, 6613 | ||||
| (100mM KCl, 0mM Mg2+) | 429 | |||||
| K1=0.9 | ||||||
| K2=0.4 | ||||||
| K3=4.1 | ||||||
| K4=10.3 | ||||||
| (100mM KCl, 3mM Mg2+) | ||||||
| K1=10.1 | ||||||
| K2=3.1 | ||||||
| K3=1000 | ||||||
| K4=0.58 | ||||||
| (400mM KCl, 3mM Mg2+) | ||||||
| K1=22.2 | ||||||
| K2=8.8 | ||||||
| K3=3.6 | ||||||
| K4=110 | ||||||
| 8 | CDC | CDC31 and Caltractin | Molecular Weight | 19459 (caltractin) | 6254, 6124 | |
| 18757 (CDC31 product) | ||||||
| pI | 5.3 (apparent, caltractin) | 6256 | ||||
| 9 | CAL | Cal-1 | Molecular Weight | 18707 | 6423 | |
| 10 | CAST | CAST (Solanum) | Molecular weight | 23141 (Betula verrucosa) | ||
| 22606 (Solanum) | ||||||
| 11 | CLNB | Calcineurin B | Molecular Weight | 19200 (Bos) | 6105, 6308, 6364, 6231 | |
| 19639 (Saccharomyces) | ||||||
| 20291 (Rattus, calcineurin-like protein) | ||||||
| A280 (1%, 1cm) | 3.1 (Bos) | |||||
| 12 | P22 | p22 | ||||
| 13 | VIS | Visinin and recoverin | Molecular weight | 24000 (Gallus, visinin) | ||
| 22142 (Rattus, brain, visini-like protein) | ||||||
| pI | 5.1 (Galus, visinin) | |||||
| 14 | CALS | calsenilin (Homo) | Molecular weight | 29230 | ||
| 15 | DREM | DREAM (Homo) | Molecular weight | 31.8 kDa | Nature 398:80-84 (1999) | |
| 16 | CMPK | CAM dependent protein kinase (Lilium) | Molecular weight | 57886 | ||
| 17 | SOS3 | sos3 gene product | Molecular weight | 25693 | ||
| 18 | RTC | Reticulocalbin | Molecular weight | 45 kDa (mouse, Cab45) | J. Cell. Biol. 133:257-268 (1996) | |
| 44000 (reticulocalbin) | J. Biol. Chem. 268:699-705 (1993) | |||||
| 40000 (PfERC) | Mol.Biochem.Parasitol. 98;283-293 (1997) | |||||
| 19 | SCF | DNA supercoiling factor | Molecular weight | 45 kDa (Drosophila cytoplasmic) 30 kDa (Drosophila nuclear fraction) | Mol. Cell. Biol. 18:6737-6744 (1998) | |
| 20 | CALP | calpain | Molecular weight | 80350 (Gallus, calpain large subunit) | ||
| 81889 (Homo, u-calpain large subunit) | ||||||
| 28238 (Oryctolagaus, calpain small subunit) | ||||||
| 94084 (Rattus, p94) | ||||||
| pI | 4.5-4.9 | 94 | ||||
| Kd (uM) [Ca2+] | 61 (Gallus, large) | 390 | ||||
| 130 (Oryctolagus, large) | ||||||
| 35 (Oryctolagus, u-large) | ||||||
| 150 (Oryctolagus, small) | ||||||
| ~200 (for 50% activation - Gallus) | ||||||
| ~750 (Oryctolagus, m-calpain) | ||||||
| 50 (Oryctolagus, u-calpain) | ||||||
| 21 | SORC | sorcin | Molecular weight | 24010 (Homo, grancalcin) | ||
| 28 kDa (Human grancalcin) | Biochem. J. 286:549-554 (1992) | |||||
| 22000 (Human sorcin) | Cancer Res. 48:3173-3178 (1988) | |||||
| pCa | 4.7-3.1 (Sorcin, synexin binding) | J. Biol. Chem. 272:22182-22190 (1997) | ||||
| 22 | S100 | S100 | Stokes radius (A) | 25.3 (Homo,S100P) | 5179 | |
| Molecular weight | 10400 (Bos, alpha) | |||||
| 10507 (Bos, beta) | ||||||
| 11429 (Oryctolagus, calgizzarin) | ||||||
| 11180 (Sus, calgizzarin) | ||||||
| 10945 (Sus, p10) | ||||||
| 10835 (Homo, MRP-8) | ||||||
| 13242 (Homo, MRP-14) | ||||||
| pI | 4.6 (Homo, S100P) | 5179, 6484, 6119 | ||||
| 5.8 (Gallus, calgizzarin) | ||||||
| 5.7-5.8 (Rattus, CAPL) | ||||||
| Kd (uM) [Ca2+] | 1.6 and 800 (Homo, S100P) | 6126, 6220 | ||||
| 100 (n=2/monomer, Bos, S100L) | ||||||
| [Ca2+] 0.5 (mM) [n sites/dimer] | 0.50 (n=4, S100B) | BioMetals 11:383-397 (1998) | ||||
| 0.29 (n=4, S100A1) | ||||||
| 0.47 (n=4, S100A2) | ||||||
| 35 (n=??, S100A3) | ||||||
| 0.15 (n=4, S100A4) | ||||||
| 0.013 (n=4, S100A5) | ||||||
| 0.32 (n=4, S100A6) | ||||||
| 0.52 (n=4, S100A11) | ||||||
| 0.05 (n=2, S100A12) | ||||||
| 0.002/0.8 (n=4, S100P) | ||||||
| [Zn2+] 0.5 (uM) [n sites/ dimer] | 500 (n=6-8, S100B) | BioMetals 11:383-397 (1998) | ||||
| 4.5 (n=4, S100A2) | ||||||
| 11 (n=8, S100A3) | ||||||
| 2000 (n=4, S100A6) | ||||||
| <0.1 (n=2, S100A12) | ||||||
| 23 | ICBP | Intestinal Ca binding protein | Molecular weight | 8501 (Bos, calbindin) | ||
| 24 | HYFL | Trichohyalin and profilaggrin | ||||
| 25 | DGK | Diacylglycerol kinase | Molecular weight | 82671 (Homo) | ||
| 82605 (Sus) | ||||||
| Kd (uM) [Ca2+] | 11.0 (Half max. enzyme activation, Sus) | 6421 | ||||
| 26 | NUBN | Nucleobindin | Molecular weight | 63000 | J. Biol. Chem. 270:6125-6133 (1995) | |
| 26 | NEFA | Nulear EF-hand acidic gene product | ||||
| Kd (Fluorescence titration, microM) | 0.08 (1 site), 0.2 (1 site) | BBRC 260(1):1-8 (1999) | ||||
| 27 | CRGP | Calmodulin-related gene product | Molecular weight | 9012 | ||
| 28 | ACTN | alpha-Actinin | Stokes radius (A) | 67 (Homo, platelet) | 2991 | |
| 76.9 (Oryctolagus, skeletal muscle) | ||||||
| Molecular weight | 105365 (Homo, placena) | 2991 | ||||
| 104200 (Gallus, skeletal) | ||||||
| 102785 (Gallus, fibroblast) | ||||||
| 97600 (Dictyostelium) | ||||||
| 20800 (Homo, platelet, native dimer) | ||||||
| 201000 (Oryctolagus, skeletal muscle) | ||||||
| 29 | FDRN | alpha-Spectrin | ||||
| 30 | GPD | Glycerol phosphate dehydrogenase | ||||
| 31 | AIF1 | Allograft inflammatory factor | ||||
| 32 | BM40 | Osteonectin and SPARC | Molecular Weight | 43000 (Rat) | BBRC 167:1393-1399 (1990) | |
| 43000 (Xenopus) | Biochem. J. 281:513-517 (1992) | |||||
| Kd (ca) | 0.6 mM (intrinsic fluorescence) | Eur. J. Biochem. 205:233-240 (1992) | ||||
| 0.08 mM (fluorescence titration) | J. Mol. Biol. 238:563-574 (1994) | |||||
| 33 | QR1 | QR1 and SC1 | Molecular Weight | 100-103 kDa (extracellualr matrix), 108 and 60 kDa (soluble form) | Mech Dev. 54:237-250 (1996) | |
| 34 | EF12 | O. v. 62K protein | Molecular weight | 62637 (AAC69510, C. elegans) | ||
| 35 | LPS | Lytechinus pictus SPEC-resembling protein | Molecular weight | 34000 | 6515 | |
| 36 | CLBN | Calbindin 28kDa | Molecular Weight | 30036 (Gallus calbindin) | 6415 | |
| 29994 (Rattus calbindin) | ||||||
| 29851 (Bos calbindin) | ||||||
| 30025 (Homo calbindin) | ||||||
| 29863 (Mus calbindin) | ||||||
| 30946 (Gallus calretinin) | ||||||
| 31389 (Homo calretinin) | ||||||
| pI | 4.6 (Mus, calbindin) | 6391 | ||||
| 5.1 (Mus, calretinin) | ||||||
| kD (uM) [Ca2+] | 2000.1.1 | 276 | ||||
| 37 | EP15 | EP15 | Molecular weight | 142 kDa (Major component), 155 kDa (Minor component) | Mol. Cell Biol. 13(9):5814-5828 (1993) | |
| 38 | TCBP | Tetrahymena calcium-binding protein | Molecular weight | 24702 (TCBP-25) | ||
| 23413 (TCBP-23) | ||||||
| pI | 4.5 | 5267 | ||||
| A282 (1%, !cm) | 6.5 (TCBP-10, degradation product of TCBP-25) | 5267 | ||||
| Kd (uM9) | 27 (n=1) (TCBP-10) | 5267 | ||||
| 39 | P26 | p26olf | Molecular weight | 26 kDa (24493, calculated molelucular mass) | BBRC 251:860-867 (1998) | |
| 40 | PLC | Phospholipase C | Molecular weight | 138714 (PLC-BETA-1, Bos) | ||
| 85962 (PLC-DELTA-1, Rattus) | ||||||
| 100547 (PLC-1, yeast) | ||||||
| 41 | CBP | CBP1 and CBP2 | Molecular weight | 20 kDa | FEBS lett. 382(1-2):198-202 (1996) | |
| 42 | PFS | Membrane associated protin of Plasmodium faciparum | Molecular weight | 43500 | 6409 | |
| pI | 4.9-5.2 | 6409 | ||||
| 43 | CDPK | Calcium dependent protein kinase | Stokes redius (A) | 29.5 | 5729 | |
| S-value (S) | 4.06 | 5729 | ||||
| Molecular Weight | 52000-55000 (SDS-PAGE, Glycine) | 5729, 6242 | ||||
| 57175 (Glycine) | ||||||
| 72645 (Arabidopsis) | ||||||
| 6100 (SDS-PAGE, Oat) | 6141, 4181 | |||||
| 79000 (minor, SDS-PAGE, Oat) | ||||||
| [Ca2+] for 1/2 max (uM) | 2 (Glycine, lipid independent) | 5208, 4181 | ||||
| 2-4 (oat, lipid dependent) | ||||||
| Km/Vmax (umol min-1 mg-1) | Mg2+-ATP: 8uM/ 1.7 | 5729 | ||||
| Mg2+-GTP: 777uM/ 0.5 | ||||||
| Histone III-S: 0.16 mg/ml-1/ 0.93 | ||||||
| Gizzard myosin light chain: 0.32 mg ml-1/ 0.62 | ||||||
| 44 | PFPK | Plasmodium falciparum protein kinase | Molecular weight | 60799 | ||
| 45 | SPEC | Strongylocentrus purpuratus ectodermal calcium-binding protein | Molecular weight | 18193 (Stringylocentrous, 1c) | ||
| 117014 (Stringylocentrous, 2a) | ||||||
| 16933 (Stringylocentrous, 2c) | ||||||
| 16739 (Hemicentrotus) | ||||||
| pI | 5.5-6.0 | 6146 | ||||
| 46 | TPP | p24 Thyroid protein | Molecular Weight | 24000 (SDS-PAGE) | 6320 | |
| 21104 (Canis) | ||||||
| 22844 (crayfish CCBP-23, ESI/MS) | EJB 227:97-101 (95) | |||||
| 22669.9 (crayfish CCBP-23, from sequence) | ||||||
| pI | 5.4 | 6320 | ||||
| 5.4 (crayfish, major) | EJB 227:97-101(95) | |||||
| 5.0 (crayfish CCBP-23, minor) | ||||||
| 5.4 (lobster, major) | ||||||
| 5.2 (lobster, minor) | ||||||
| 47 | 1F8 | 1F8 | Molecular weight | 23000 | ||
| pI | 4.5 (calc.) | 6187 | ||||
| kD (uM) [Ca2+] | < 50 (n<2) | 6187 | ||||
| 48 | SARC | Sarcoplasmic calcium-binding protein | Molecular weight | 20119 (Patinopectin) | ||
| 19556 (Perinereis) | ||||||
| 19485 (Nereis) | ||||||
| 21643 (Astacus, alpha) | ||||||
| 21960 (Penaeus, beta) | ||||||
| 21972 (Penaeus, alphaB) | ||||||
| 21571 (Penaeus,alphaA) | ||||||
| pI | 4.8 (Nereis) | 287, 224 | ||||
| 5.06 (Astacus) | ||||||
| 5.00 (Patinopecten) | ||||||
| 4.85 (Amphioxus) | ||||||
| A280 (1%, 1cm) | 10.6 (Astacus) | |||||
| 9.7 (Nereis) | ||||||
| 7.1 (Patinopecten) | ||||||
| 20 (Amphioxus) | ||||||
| Kd (uM) [Ca2+] | K1=0.006 | 287 | ||||
| K2=10.000 | ||||||
| K3=0.006 | ||||||
| Kd (uM) [Mg2+] | K1=230 | |||||
| K2=63 | ||||||
| K3=15 | ||||||
| 49 | AEQ | Aequorin and luciferin-binding protein | Stokes radius (A) | 23 (Renilla, luciferin BP) | 5160 | |
| S-value (S) | 2.32 (Renilla, luciferin BP) | 5160 | ||||
| Molecular weight | 21459 (apo) (Aequorea, aequorin) | |||||
| 21914 (holo) (Aequorea) | ||||||
| 20541 (Renilla, liciferin BP) | ||||||
| pI | 4.2-4.9 (Aequorea, aequorin) | 1499, 5160 | ||||
| 4.3 (Renilla, lucuferin BP) | ||||||
| A280 (1%, 1cm) | 27.0 (Aequorea) | 4312 | ||||
| Kd (uM) [Ca2+] | 0.2 (n=2) (Renilla) | |||||
| 0.14 (n=3) (Aequorea) | 5160, 236 | |||||
| 50 | PPTS | Protein phosphatase, threonine and serine | Molecular weight | 75510 | 6446 | |
| 51 | H32 | HRA32 | Molecular weight | 17 kDa | Mol. Plant Microbe Interact. 12(8):712-719 (1999) | |
| 52 | EFH5 | EFH5 | Molecular Weight | 21700 (Trypanosoma) | 6513 | |
| 53 | CVP | Calcium vecotr protein | Molecular weight | 18267 | 6289 | |
| pI | 4.9 | 5170 | ||||
| A280 (1%, 1cm) | 7.5 | 5170 | ||||
| Kd (uM) [Ca2+] | 0.12 | 5170 | ||||
| 54 | PMAT | Arabidopsis membrane associating Protein | ||||
| 55 | LAV | LAV1 | Molecular Weight | 40503 | 6315 | |
| pCa(1/2) | 6.5 (CBP40, recombinant) | Biochemistry 39:3827-34 (00) | ||||
| 4 mol/mol | ||||||
| 4.6 (CBP40, EF-hands only) | ||||||
| 56 | CMSE | Saccharopolyspora calcium-binding protein | Molecular weight | 20090 | ||
| 57 | MSV | Entomopoxvirinae MSV097 | Molecular weight | 15930 | ||
| 58 | PARV | Parvalbumin | S-Value (S) | 1.7 (Raja) | 224 | |
| 1.6 (Cyprinus) | ||||||
| 1.45 (Graptemys) | ||||||
| 1.45 (Gallus) | ||||||
| 1.45 (Oryctolagus) | ||||||
| Molecular Weight | 11850 (Rattus, oncomodulin) | |||||
| 11820 (Raja) | ||||||
| 11580 (Cyprinus) | ||||||
| 11620 (Rana) | ||||||
| 12140 (Oryctolagus) | ||||||
| pI | 3.9 (Rattus, oncomodulin) | 128, 427, 224 | ||||
| 4.35 (Gallus, avian thymic hormone) | ||||||
| 4.45 (Raja) | ||||||
| 4.25 (Cyprinus) | ||||||
| 4.50 (Rana) | ||||||
| 4.4 (Graptemys) | ||||||
| 4.9 (Gallus) | ||||||
| 4.9 (Oryctolagus) | ||||||
| A259 (1%, 1cm) | 1.92 (Raja) | 224, 128 | ||||
| 1.76 (Cyprinus) | ||||||
| 2.06 (Rana) | ||||||
| 2.04 (Graptemys) | ||||||
| 1.88 (Gallus) | ||||||
| 1.51 (Oryctolagus) | ||||||
| 2.7 (Rattus, oncomodulin) | ||||||
| Kd (uM) [Ca2+] | 6.6 (Oryctolagus alpha) | 311, 286 427 | ||||
| 7.8 (Rana alpha) | ||||||
| 2.2 (Rana beta) | ||||||
| >1 (n=2) (oncomodulin) | ||||||
| 0.45 (oncomodulin) | ||||||
| 0.59 (oncomodulin) | ||||||
| 0.008 (avian thymic hormone) | ||||||
| 0.01, 0.08 (avian thymic parvalbumin CVP3) | 7225 | |||||
| 0.04 (Rat n=2) | ||||||
| 0.04 (Rat F102W mutant) | 6869 | |||||
| Kd (uM) [Mg2+] | 16 (Oryctolagus alpha) | 311, 286, 427 | ||||
| 21 (Rana alpha) | ||||||
| 27 (Rana beta) | ||||||
| 68 (avian thymic hormone) | ||||||
| 34 (Rat) | ||||||
| 22 (Rat F102W mutant) | 6869 | |||||
| 59 | FIMB | Fimbrin | Molecular weight | 65000 | Cancer Res. 56(1):138-144 (1996) | |
| 60 | GRP | Ras guanyl nucleotide-releasing protein | Molecular weight | 90258 | ||
| 61 | PKD | PKD2L/polycystin | Molecular weight | 109790 (POLYCYSTIN 2, Homo) | ||
| 62 | RYN | Ryanodine receptor/Ca release channel | Molecular weight | 563584 | JBC 265(4):2244-2256 (1990) | |
| Hill dissociation constant and coefficient | 0.9 mM, 1.4 (lobster, 2 calcium ions) | Biochemistry 37(14):4804-4814 (1998) | ||||
| 3.7 mM, 1.1 (rabbit skeletal, 2 calcium ions) | Biochemistry 37(14):4804-4814 (1998) | |||||
| 3.8 mM, 1.3 (rabbit cardiac, 2 calcium ions) | Biochemistry 37(14):4804-4814 (1998) | |||||
| 63 | CBL | Prot-oncogene Cbl | Molecular weight | 99646 (PROTO-ONCOGENE C-CBL, Homo) | ||
| 64 | CIB | Ca & integrin binding protein | ||||
| 65 | SENS | Calsensin | ||||
| 66 | GRV | Groovin | Molecular weight | 472276 (Groovin, Drosophila) | ||