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__________ |
___________________ |
___________ |
__________ |
__________ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
table1 |
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Subfamilies of EF-hands |
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Subfamily |
description |
Kingdom |
Function |
Structure |
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1 |
2 |
3 |
4 |
5 |
6 |
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Animal Plant Fungi Protist |
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( |
7 |
8 |
9 |
10 |
11 |
12 |
) |
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-- CTER --- |
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CAM |
calmodulin |
APFP |
+ |
X |
|
+ |
+ |
+ |
+/- |
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TNC |
troponin C |
A... |
+ |
X |
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+/- |
+ |
+/- |
+ |
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ELC |
essential light chain, myosin |
A.F. |
+ |
X |
|
a/- |
+/- |
+/- |
+/- |
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RLC |
regulatory light chain |
A.FP |
+ |
X |
|
+ |
- |
- |
- |
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TPNV |
troponin, nonvertebrate |
A... |
+ |
? |
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- |
+ |
+/- |
+ |
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CLAT |
CAM-like leaf (Arabidopsis)
|
.P.. |
? |
? |
|
+ |
+ |
+ |
+ |
*** |
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SQUD |
squidulin (Loligo)
|
A... |
+ |
? |
|
+ |
+ |
+ |
+ |
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CDC |
CDC31 & caltractin |
APFP |
? |
? |
|
+ |
+/- |
+/- |
+ |
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CAL |
cal1 (Caenorhabditis)
|
A... |
? |
? |
|
+ |
+ |
+ |
+ |
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CAST |
CAST |
.P.. |
? |
? |
*** |
+ |
- |
+ |
+ |
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--- CPV --- |
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CLNB |
calcineurin B |
A.F. |
+ |
X |
|
+ |
+ |
+ |
+ |
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P22 |
p22 |
A... |
? |
? |
|
+ |
- |
+ |
+ |
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VIS |
visinin & recoverin |
A... |
+ |
X |
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- |
+ |
+ |
- |
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CALS |
calsenilin (Homo)
|
A... |
? |
? |
*** |
- |
- |
+ |
+ |
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DREM |
DRE antag. modul. (Homo)
|
A... |
+ |
? |
*** |
-/? |
+/? |
+ |
+ |
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CMPK |
CAM dep prot kinase (Lilium)
|
.P.. |
+ |
? |
*** |
+ |
+ |
+ |
+ |
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SOS3 |
Ca sens homo (Arabidopsis)
|
.P.. |
+ |
? |
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- |
- |
- |
- |
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--- Pairings --- |
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RTC |
reticulocalbin (Mus)
|
A... |
? |
? |
|
+ |
?/+ |
?/+ |
+ |
+ |
+ |
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SCF |
DNA supercoil fact (Bombyx)
|
A... |
? |
? |
*** |
+ |
- |
+ |
+ |
+ |
+ |
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------ |
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CALP |
calpain |
A... |
+ |
X |
*** |
+ |
+ |
- |
- |
- |
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SORC |
sorcin / grancyclin |
A.F. |
+ |
? |
*** |
+ |
+ |
- |
- |
- |
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------ |
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S100 |
S100 |
A... |
? |
X |
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b/- |
+ |
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ICBP |
intestinal Ca binding protein |
A... |
? |
X |
|
b/- |
+ |
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HYFL |
trichohylin profilag |
A... |
? |
? |
|
b/? |
+ |
*** |
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------ |
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DGK |
diacylglycerol kinase |
A... |
+ |
? |
*** |
+ |
+ |
*** |
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NUBN |
nucleobindin & NEFA |
A... |
? |
? |
*** |
+ |
+ |
*** |
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CRGP |
CAM rel gene product (Homo)
|
A... |
? |
? |
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+ |
+ |
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------ |
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ACTN |
alpha-actinin |
A.F. |
+ |
? |
*** |
+/- |
+/- |
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FDRN |
alpha-spectrin & alpha-fodrin |
A... |
+ |
? |
*** |
- |
- |
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------ |
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GPD |
Glycerol-P-dehydrogenase |
A... |
+ |
? |
*** |
- |
+ |
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AIF1 |
allograft inflammatory factor |
A... |
? |
? |
*** |
+ |
+/? |
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------ |
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BM40 |
osteonectin, SPARK |
A... |
? |
X |
*** |
c |
+ |
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QR1 |
QR1 & SC1 |
A... |
? |
? |
|
- |
+ |
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--- Self --- |
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EF12 |
Ca Binding prot of nematodes |
A... |
? |
? |
*** |
+ |
+ |
+ |
- |
+ |
+ |
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+ |
+ |
+ |
+ |
+ |
+ |
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LPS |
L. pictus SPEC resembl prot |
A... |
? |
? |
|
+ |
+ |
+ |
+ |
+ |
+ |
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+ |
- |
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CLBN |
calbindin 28kDa, calretinin |
A... |
? |
? |
|
+ |
+/- |
+ |
+ |
+ |
- |
|
EP15 |
EP15 |
A... |
? |
? |
|
- |
- |
- |
+ |
+ |
- |
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TCBP |
Tetrahymena CaBP |
...P |
? |
? |
|
- |
+ |
+ |
+ |
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P26 |
p260lf (Rana)
|
A... |
? |
? |
|
- |
- |
*** |
- |
- |
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PLC |
phopholipase C |
A.F. |
+ |
X |
*** |
- |
- |
- |
- |
*** |
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CBP |
CBP1, CBP2 (Dictyostelium)
|
..F. |
? |
? |
|
+ |
+ |
+ |
+ |
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--- Miscellaneous --- |
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PFS |
surface protein (Plasmodium)
|
...P |
? |
? |
*** |
+ |
+ |
+ |
+ |
+ |
- |
*** |
CDPK |
Ca dependent protein kinase |
.P.. |
+ |
? |
*** |
+ |
+ |
+ |
+ |
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PFPK |
protein kinase (Plasmodium)
|
...P |
+ |
? |
*** |
+ |
+ |
+ |
+ |
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SPEC |
Strongylocentrotus CaBP |
A... |
? |
? |
|
+/- |
+ |
+ |
+/- |
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TPP |
p24 thyroid protein |
A... |
? |
? |
|
+ |
+ |
+ |
? |
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1F8 |
1F8 & TB17 & calflagin |
...P |
? |
? |
|
+ |
+ |
+ |
+ |
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SARC |
sarcoplasm Ca bind prot |
A... |
? |
X |
|
+ |
+/- |
+ |
+/- |
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AEQ |
aequorin & luciferin BP |
A... |
+ |
X |
|
+ |
*-* |
+ |
+ |
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PPTS |
protein phosphatase |
A... |
+ |
? |
*** |
- |
*-* |
+ |
+ |
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H32 |
HRA32 (Phaseolus)
|
.P.. |
? |
? |
|
+ |
+ |
+ |
+ |
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EFH5 |
EFH5 |
...P |
? |
? |
|
- |
+/- |
+/- |
- |
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CVP |
Ca vector P (Branchiostoma)
|
A... |
? |
? |
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- |
- |
+ |
+ |
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PMAT |
memb. assoc. (Arabidopsis)
|
.P.. |
? |
? |
*** |
+ |
+ |
+ |
+ |
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LAV |
LAV1 (Physarum)
|
..F. |
? |
? |
*** |
+ |
+ |
+ |
+ |
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CMSE |
CaBP (Saccharopolyspora)
|
bact |
? |
? |
|
+ |
+ |
+ |
+ |
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MSV |
MSV097 (Entomopoxvirinae)
|
virus |
? |
? |
|
+ |
+ |
- |
- |
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PARV |
parvalbumin |
A... |
? |
X |
|
del |
- |
+ |
+ |
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FIMB |
fimbrin |
A.F. |
+ |
? |
|
+/- |
+/- |
*** |
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GRP |
ras GRP (Rattus)
|
A... |
? |
? |
*** |
+/? |
+/? |
*** |
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PKD |
PKD2L / polycystin |
A... |
? |
? |
*** |
- |
+ |
*** |
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RYR |
ryanodine R / Ca release |
A... |
+ |
? |
*** |
- |
+ |
*** |
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CBL |
proto-oncogene Cbl |
A... |
+ |
X |
*** |
- |
d |
*** |
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CIB |
Ca & integrin BP |
A... |
? |
? |
*** |
+ |
+ |
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SENS |
calsensin (Haemopsis)
|
A... |
? |
? |
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+ |
+ |
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GRV |
groovin (Drosophila)
|
A... |
? |
? |
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+ |
+ |
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update: Oct. 06, 2000 |
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__________ |
___________________ |
___________ |
__________ |
__________ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
_____ |
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